تاثیر رژیم درمانی کوتاه مدت بر لیپیدهای خون در افراد مبتلا به هیپر لیپیدمی مرکز تحقیقات عوامل خطرزای سلامت - دانشگاه علوم پزشکی کرمانشاه

نوع مقاله: مقاله پژوهشی

نویسندگان

1 استادیار علوم تغذیه ،دانشکده بهداشت ، دانشگاه علوم پزشکیکرمانشاه، کرمانشاه، ایران

2 کارشناس علوم تغذیه ،دانشکده بهداشت ، دانشگاه علوم پزشکی کرمانشاه، کرمانشاه، ایران

3 کارشناس بهداشت عمومی ،دانشکده بهداشت ، دانشگاه علوم پزشکی کرمانشاه، کرمانشاه، ایران

4 کارشناس بیولوژی ،دانشکده پیرا پزشکی ، دانشگاه علوم پزشکی کرمانشاه، کرمانشاه، ایران

5 استادیار آمار زیستی ،دانشکده بهداشت دانشگاه علوم پزشکی کرمانشاه، کرمانشاه، ایران

چکیده

مقدمه 
هیپرلیپیدمی یکی از علل ابتلاء به بیماری قلبی - عروقی است که با رعایت رژیم غذایی و تغییر سبک زندگی قابل پیشگیری وکنترل می باشد. این مطالعه با هدف بررسی تاثیر رژیم درمانی درکاهش لیپیدهای خون در افراد هیپر لیپیدمیک انجام شد . روش کار
 این مطالعه کارآزمایی بالینی بوده و در سال 1389 در دانشکده بهداشت دانشگاه علوم پزشکی کرمانشاه انجام شده است.73 نفر از 185 نفر شرکت کنندگان مطالعه قبلی که دارای درجاتی از هیپرلیپیدمی بودند جهت بررسی بیشتر در مطالعه شبه کارآزمایی بالینی انتخاب شدند . پس از اخذ رضایت نامه، برای اندازه گیری چربیهای خون (5 (T-C ,LDL-C ,HDL-C,TG میلی لیتر خون ناشتا ازشرکت کنندگان گرفته شد. ترکیب بدن افراد با استفاده از دستگاه (Body Analyzer PlusAvis 333) تعیین گردید. رژیم غذایی کم چرب،کم کلسترول با فیبر بالا تجویز شد. پس از دو ماه متغیر ها مجددا اندازه گیری و مقدار قبل و بعد از مطالعه بااستفاده از روش تی تست مورد تجزیه وتحلیل آماری قرار گرفتند .
 نتایج تعداد 45 نفر بامیانگین سنی45±8 سال مطالعه را تکمیل کردند . بر اساس یافته ها رعایت رژیم کم چرب،کم کلسترول و پر فیبر موجب کاهش وزن و BMI گردید ( p< /0 05). میزان LDL-C ه ب طور معنی داری کاهش یافت (p /0= 001). فشار خون دیاستولیک به طور مرزی کاهش نشان داد (p= /0 059). تغییر معنی داری در TG,T-C و فشار خون سیستولیک مشاهده نشد . نتیجه گیری کاهش معنی دارLDL-C ، وزن و BMI افراد بعد از یک دوره کوتاه مدت نشانگر تاثیرآموزش و رعایت رژیم غذایی مناسب در کنترل وزن و چربیهای خون می باشد. توصیه به رعایت رژیم غذایی صحیح می تواند موجب ارتقاءسطح آگاهی های تغذیه ای مردم و کاهش چربیهای خون گردد 

کلیدواژه‌ها


عنوان مقاله [English]

The Effect of Short Time Diet Therapy on Lipid Profiles in Hyperlipidemia Public Health Research Center, Kermanshah University of Medical Sciences

نویسندگان [English]

  • Yahya Pasdar 1
  • Parisa Niazi 2
  • Shokoufeh Alghasi 3
  • Esmat Rashidi 4
  • Mansour Rezaei 5
1 Assisstant Profesor of Nutrition, Kermanshah University of Medical Sciences, Kermanshah, Iran
2 BSc in Nutrition, Kermanshah University of Medical Sciences, Kermanshah, Iran
3 BSc in Public Health,Kermanshah University of Medical Sciences, Kermanshah, Iran
4 BSc in Biology, Kermanshah university of Medical Scienes,Kermanshah, Iran
5 Assisstant Professor of Biostatistic,Kermanshah university of Medical Scienes,Kermanshah, Iran
چکیده [English]

Introduction
Hyperlipidemia is a risk factor for cardio vascular diseases (CVD), which may be protected by diet therapy and physical activity. The aim of the present study was the determination of the effects of diet therapy and nutritional education on lipid profiles in hyperlipidemic pateints.
Materials and Methods
73 subjects out of 183 subjects with hyperlipidemia were selected from our previous research for this semi-clinical trial study. Written consent forms were obtained and 5ml fasting blood sample was collected for TG, T-C, LDL-C and HDL-C analysis before and after intervention. Body composition was assessed using bioelectric impedance (Plusavis 333). All participants received low fat, low cholesterol and high fiber diet including a nutritional guide booklet. Subjects were followed up using phone call every two weeks and data was analyzed using pair T-test and SPSS16.
Results
45 subjects with average age of 45+8 year completed the study (16 female and 29 male). There was significant reduction in BMI and weight after two months diet therapy (p<0.05). Significant decrease was showed in LDL-C after two month intervention (104.2+2.3 vs. 90.1+2.9, p= 0.001). The study showed borderline reduction in diastolic blood pressure. There was no significant difference for TG, T-C and systolic blood pressure before and after intervention. Conclusion
Reduction in BMI, weight and LDL-C during short time revealed the effects of diet therapy and nutritional education. Screening for hyperlipidemia and improving public nutritional knowledge using appropriate media to prevent CVD is highly recommended.

کلیدواژه‌ها [English]

  • Cholesterol
  • Hyperlipidemia
  • HDL
  • LDL
  • TG
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