Investigating the Risk Factors of Cholelithiasis in Morbid Obese Patients Undergone Bariatric Surgery
Ali
Jangjoo
Associated Professor of Surgery,Surgical Oncology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
author
Mohammad Javad
Ghamari
Fellowship of minimal invasive surgery/Surgical oncology research center, Mashhad university of medical sciences, Mashhad, Iran
author
Maryam
Beyranvand
Medical Student/Surgical Oncology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
author
Mona
Najaf Najafi
Assistant Professor of Community Medicine/Clinical Research Unit, Mashhad University of Medical Sciences, Mashhad, Iran
author
Elahe
Amini
Medical Student/Surgical Oncology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
author
Arash
Arianpoor
Medical Doctor/Surgical Oncology Research Center
author
text
article
2017
per
Introduction: Morbid obesity is well-known risk factor of cholelithiasis. On the other hand, rapid weight loss following bariatric surgery, as a treatment of morbid obesity, can cause the formation of gallstones. In this inquiry we decided to investigate the risk factors of cholelithiasis and evaluate the need for prophylactic cholecystectomy during bariatric surgery. Materials and Methods: All desired information of patients with morbid obesity who underwent bariatric surgery during 2011-2017 in surgical ward of Imam Reza hospital of Mashhad were extracted from patients' documents. All data were analyzed using SPSS software. Results: Totally 150 patients were enrolled in this study from which 127 patients did not have any history of cholelithiasis, 46.5% of patients without any history of cholelithiasis and 73.9% of patients with a history of this condition were positive for gastric H. pylori (p<0.05). Conclusion: In conclusion in our study the only factor associated with gallstone formation was H. pylori infection. Although H. pylori infection cannot be considered as a concrete reason for prophylactic cholecystectomy merely based on our results, its treatment should be kept in mind as a treatable risk factor of cholelithiasis.
medical journal of mashhad university of medical sciences
1735-4013
60
v.
5
no.
2017
662
669
https://mjms.mums.ac.ir/article_10449_64b8d07826803d097f92e68a0e119309.pdf
dx.doi.org/10.22038/mjms.2017.10449
Effectiveness of Hypnotherapy on the
Perceived Stress and Blood Pressure in Patients with Primary Hypertension
fatemeh
heidaran
M.A of General Psychology, Department of Psychology, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran
author
ilnaz
sajjadian
Assistant Professor, Department of Clinical Psychology, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran.
author
Mahdi
Fathi
Associate Professor of Anesthesiology, Medical Sciences, Mashhad, Iran.
author
text
article
2017
per
Introduction: Hypertension is the most common cardiovascular disease risk factors, that leads to many problems in the elderly, and perceived stress leads to increased blood pursue and loss of performance. However, due to the importance of hypertension, the aim of this study was the effectiveness of hypnosis therapy on the amount of perceived stress and blood pressure in patients with primary hypertension. Materials and Methods: The research method was semi- experimental with pre and posttest. For this purpose, among patients with primary hypertension referred to health centers in Mashhad in the period of summer 2015, with available sampling 30 number were selected and distributed in two groups of experience and control randomly (15 persons). Subjects in the two groups, before and after intervention, answered to perceived stress questionnaire completed the blood pressure record chart for 15 days before and after the intervention at twice in the morning and evening. The experimental group received three sessions hypnosis therapy, but no intervention was carried out in control group. Results: The results of covariance analyze showed that hypnosis therapy was effective on decreasing the amount of perceived stress and blood pressure, in patients with primary hypertension. Conclusion: According to the results, hypnotherapy can be used to reduce perceived stress and blood pressure in patients with high blood pressure.
medical journal of mashhad university of medical sciences
1735-4013
60
v.
5
no.
2017
669
680
https://mjms.mums.ac.ir/article_10451_1d827569ddb9b830d6e97396cdd35ef3.pdf
dx.doi.org/10.22038/mjms.2017.10451
Association between rs3745453 Gene Polymorphism and
the Risk of Multiple Sclerosis
Zeynab
Golshani
Department of Biology, Marvdasht branch, Islamic Azad University, Marvdasht , Fars, Iran
author
Zohreh
Hojati
Department of Biology, Faculty of Sciences, University of Isfahan, Isfahan, Iran
author
Ali
SHarifzadeh
Department of Microbiology, Islamic Azad University Shahrekord branch, Shahrekord, Iran.
author
Vahid
SHaygannejad
Isfahan Neurosciences Research Center, Alzahra Hospital, Department of Neurology, Isfahan University of Medical Sciences, Isfahan, Iran
author
Mojtaba
Jafarinia
Department of Biology, Marvdasht branch, Islamic Azad University, Marvdasht , Fars, Iran
author
text
article
2017
per
Introduction: Multiple Sclerosis (MS) is a major autoimmune disease of the central nervous system. Today it is specified that changes in the sequence of single nucleotides or SNPs are associated with disease or resistance to disease. In recent studies, the association of micro-RNA polymorphism has been reported with diseases such as cancer and autoimmune diseases. Micro RNA is a group of non-coding RNA that affects a variety of biological processes such as growth, cell division, and immunity. Materials&Methods: blood samples were collected from 71 MS patients and 71 healthy subjects, and DNA was extracted. Genotyping analysis was performed using TARMS PCR technique. The relationship between rs3745453 polymorphism and MS was evaluated by statistical tests. Results: TT, TC and CC genotypic frequencies are 34, 24 and 13 in patients and 39, 11 and 21% in control group respectively. In both groups, the TT genotype was dominant and heterozygote frequencies were higher in patients than control group. Odd ratio (OR) in TC genotype was 2.7. In other words, heterozygote individuals have a 2.7 times higher chance of MS than others Conclusion: This study was the first report of the relationship between mir23a polymorphism and MS disease. According to the results, we can say that mir 23a rs3745453 polymorphism is associated with Multiple sclerosis (P = 0.029). It is suggested that further studies should be done with more samples.
medical journal of mashhad university of medical sciences
1735-4013
60
v.
5
no.
2017
681
688
https://mjms.mums.ac.ir/article_10452_c3dde422215a3cf6a21726523421dcca.pdf
dx.doi.org/10.22038/mjms.2017.10452
A comparison of mortality rate caused by Aluminum Phosphide with other poisonings in Golestan Province, Iran, 2010 - 2016
mohamad
shokrzadeh
Associate Professor, Pharmaceutical Sciences Research Center, Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran
author
hosein
zarei
General Physician, Golestan Department of Forensic Medicine, Gorgan, Iran.
author
Jafar
Jalilian
MSc in Toxicology, Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran
author
Abolghasem
Badeli
BS in Applied Mathematics, Golestan Department of Forensic Medicine, Gorgan, Iran.
author
Faramarz
Ebrahimi Falahtalab
Forensic Medicine and Toxicology Specialist, Golestan Department of Forensic Medicine, Gorgan, Iran
author
Yaghoub
Shayeste
MSc in Toxicology, Health Management and Social Development Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
author
text
article
2017
per
Introduction: Aluminum Phosphide (ALP) is one of the most common causes of death due to poisoning worldwide. The aim of this study was a comparison of mortality rate of Aluminum Phosphide poisoning with other kinds of poisonings in Golestan Province, Iran, 2010 to 2016. Materials and Methods: This descriptive retrospective study was carried out on all referential bodies to Golestan department of forensic medicine who died due to ALP poisoning and other poisonings from March 2008 to March 2016. Data such as age, gender, marital status, occupation, education, residence, time and kind of poisoning, agent and location of poisoning and death were collected from patients’ medical records and analyzed. Results: Froma total of 420 deaths due to poisoning causes, 105 cases died from ALP (25%) which after Opioids is the second cause of death. Of 105 cases, 63.8% of them (n=67) were men and 42.9% (n=45) of cases were aged 20–29 years, 46.7% (n=49) of cases were married and 40% (n=42) of them had been educated up to high school. Moreover, 82.9% of cases (n=87) were living in urban areas. Also, 99% (n=104) of deaths caused by ALP poisoning were due to suicide attempt that occurred mostly in winter (33.3%, n=35). Conclusion: 0ur findings indicated that ALP toxicity was the second cause of death due to poisoning in Golestan province that was seen most commonly among men and due to suicide attempt.
medical journal of mashhad university of medical sciences
1735-4013
60
v.
5
no.
2017
689
690
https://mjms.mums.ac.ir/article_10453_3639908a621177a983ef34b36b202093.pdf
dx.doi.org/10.22038/mjms.2017.10453
Investigating the relation of Household Food Security Status and some Socio-economic factors with children Intelligence Quotient in 2016 - Mashhad-Iran
fatemeh
nejati
Master of Science in Ntrition, School of Medicine, Mashad University of Medical Sciences. Iran
author
Mohsen
Nemati
Associate professor Department of Nutrition, School of Medicine, Mashad University of Medical Sciences, Iran.
author
Amir Reza
Rezaei Ardani
Associate professor of psychiatry, Psychiatry and Behavioral Sciences Research Center, Mashhad University of Medical Sciences, Mashhad, Iran .
author
Davoud
Soleimani
Ph.D. Nutrition. School of Medicine, Mashad University of Medical Sciences. Iran
author
Maryam
Khosravi
Assistant Professor Department of Nutrition, School of Medicine, Mashad University of Medical Sciences, Iran.
author
Javad
Salehi fadardi
دانشیار روانشناسی، دانشکده علوم تربیتی و روان شناسی، دانشگاه فردوسی مشهد، ایران
author
Habibollah
Esmaily
Associate professor Department of Biostatistics, School of Medicine, Mashad University of Medical Sciences, Iran.
author
text
article
2017
per
Introduction: Food insecurity is one of the categories that has a serious impact on nutritional status. Intelligence quotient is an indicator of one's efficacy. Yet, limited studies have been conducted about food security status and socioeconomic factors associated with children's Intelligence quotient (IQ). The current study aimed to investigate the relationship of household food security status and some socioeconomic factors with children Intelligence quotient (IQ) in Mashhad. Materials&Methods: In this descriptive cross-sectional study, 18-item USDA food security questionnaire, 200 children in the food secure group and 200 children in the food insecure group were included. The members of each group were matched 1 to 1 in terms of age and gender..Children’s age group was 4-6 years old, 18-item Food Security (USDA) and General information Questionnaires were completed through interview with mothers. The relationship between qualitative and quantitative variables with Intelligence quotient (IQ) was determined by Chi-square, T-independent and one-way ANOVA. Results: The mean scores of verbal, performance and total IQs in food insecure group without hunger were respectively 98.75±13.24, 102.94±12.96 and 100.84±11.04, which were lower than mean of children's IQ in the food secure group (p<0.05). Also, there were significant differences between two groups in variables of head of household's occupation, mother's occupation, level of father's education, level of mother's education, the status of housing ownership and the economic situation. Conclusion: Food security is effective on Intelligence quotient (IQ) through its impact on nutrition and as a stress factor that affects the entire family.
medical journal of mashhad university of medical sciences
1735-4013
60
v.
5
no.
2017
691
700
https://mjms.mums.ac.ir/article_10454_999d4a83f8cab587f941a1173cb503b0.pdf
dx.doi.org/10.22038/mjms.2017.10454
Assessment of clinical manifestation and pulmonary function test on post tuberculosis treatment in Qom province 2005-2013
Abolfazil
Mozafari
Department of Medical Sciences, Qom Branch, Islamic Azad University, Qom, Iran.
author
Mahdi
Gholamzade
پزشک عمومی دانشگاه آزاد اسلامی قم
author
text
article
2017
per
Introduction: Despite control, prevention and the availability of drugs to cure tuberculosis, TB remains an important cause of death from an infectious agent in Iran. Pulmonary tuberculosis is more than 80% of tuberculosis cases. Regardless of new treatment, there are pulmonary sequel and decrease pulmonary function test following tuberculosis. This study is aim to assessment of clinical manifestation and pulmonary function test post tuberculosis management. Materials and Methods: In this cross-sectional study, after consideration of inclusion and exclusion criteria, finally 247 patients from 2005-2013 in Qom province were selected. Data of patients were including of demographic parameter, St George’s Respiratory Questionnaire and spirometry. For analysis, we use from Pearson correlation coefficient, student T test and chi-square test and was done in SPSS version 17 and P value below than 0.05 was significant. Results: Mean age was 48.31 years old and 64% was female. Over than half of patients have pulmonary symptoms like cough, sputum, dyspnea and abnormal pulmonary function test in spirometry. There were significant correlation between clinical finding with spirometry and severity of involvement (P<0.001). Conclusion: in spite of effective and on time treatment of tuberculosis, patients have pulmonary sequel and symptom over lives.
medical journal of mashhad university of medical sciences
1735-4013
60
v.
5
no.
2017
701
708
https://mjms.mums.ac.ir/article_10455_3ccf0ce5d84d4ac61359330f3de0a870.pdf
dx.doi.org/10.22038/mjms.2017.10455
Viral infection and chronic fatigue syndrome (CFS)
Mohammad
Derakhshan
Associate professor , Department of Clinical Bacteriology; Virology, Faculty of Medicine and Anti-microbial Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
author
Reza
Derakhshan
Intern.School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
author
text
article
2017
per
Many studies have shown that viruses after they enter the host cell can interact with mitochondria and disrupt their function; particularly some studies have determined that these effects can alter the mitochondrial structure as well as changes in the pathway for energy production. The effect of virus or viral protein on the electron transport chain, sometimes following entry of divert viruses to the host cell, will result in a sharp decrease in cellular energy at the end of the electron transport process. In addition, nowadays new data indicate that a number of viruses may affect the mitochondrial pathway of apoptosis and thus affect the respiratory chain in the mitochondria. Such effects can lead to clinical outcomes, particularly in the context of sustained infections, which can ultimately be considered as a possible cause of chronic fatigue syndrome (CFS). Therefore, as a hypothesis, it may be concluded that viral infections may be one of the main potential etiology for this syndrome.
medical journal of mashhad university of medical sciences
1735-4013
60
v.
5
no.
2017
709
713
https://mjms.mums.ac.ir/article_10458_2096bb4feebae499031286eeebc82206.pdf
dx.doi.org/10.22038/mjms.2017.10458
Clinical value of fluoroquinolone in the treatment of TB and MDR-TB
Mahdieh
Sayadi
MD of Microbiology, school of Medicine, Mashhad University of Medical Sciences , Mashhad, Iran
author
Mahsa
Sayadi
MD of Microbiology, school of Medicine, Mashhad University of Medical Sciences , Mashhad, Iran
author
Kiarash
Ghazvini
Department of Microbiology and virology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
author
text
article
2017
per
Background: Tuberculosis is a major health problem in many developing countries. The disease is caused by Mycobacterium tuberculosis bacilli, for the treatment antibiotics such as isoniazid, rifampin, pyrazinamide and ethambutol are used, Due to the reduced activity of these antibiotics and increase the resistance and MDR strains around the world, need to consider antibiotics second phase of TB treatment and alternative therapies felt. Among the second phase of treatment drugs, fluoroquinolone are the most important drugs as the second phase of TB treatment because of high pharmoacokenetics and pharmaco dynamic properties , Broad activity against Mycobacterium tuberculosis and less side effects and toxicity. As currently only fluoroquinolone is approved by the World Health Organization to be used in the treatment of sensitive TB and proved that their use shortens the duration of treatment and improve results. Materials&Methods: In the present study, 170 Article about fluoroquinolone in the treatment of pulmonary tuberculosis and MDR-TB have been reviewed. Results: According to the articles , fluoroquinolone are the latest and most powerful drug classes used in the second phase of TB treatment and In addition to being effective in the treatment of MDR-TB, affordable alternative to antibiotics in the first phase standard diet. Among the members of this groupof antibiotics ,Moxifloxacin and levofloxacin of which have the greatest activity and Have higher activity than ofloxacinBut there ofloxacin higher safety Conclusion: fluoroquinolone, as appropriate antibiotic for the treatment of MDR-TB as well as a better alternative to antibiotics in the first line.
medical journal of mashhad university of medical sciences
1735-4013
60
v.
5
no.
2017
714
726
https://mjms.mums.ac.ir/article_10460_da34431914d9957cdf18b938c2abf83f.pdf
dx.doi.org/10.22038/mjms.2017.10460