The association between anthropometric indexes and cardiovascular risk factors in academic members of Islamic azad university of Khomeinishahr
Allahyar
Arabmomeni
Faculty of Sport science, Department of Human Science, Khomeinishahr Branch, Islamic Azad University, Khomeinishahr/Isfahan, Iran
author
Laleh
Naderi
دانشجوی دکتری فیزیولوژی ورزشی، دانشکده علوم انسانی، دانشگاه آزاد اسلامی واحد خمینی شهر، خمینی شهر ، اصفهان، ایران
author
text
article
2018
per
Introduction: It is important investigative association anthropometric indexes with cardiovascular risk factors for determining cardiovascular disease. Therefore, the aim of the present study was to evaluate the relationship between anthropometric indexes and cardiovascular risk factors in academic members of Islamic Azad University of Khomeinishahr. Methods and Materials: A total of 158 (30 women and 128 men) faculty members aged between 30 to 65 years from university of Khomeinishahr were selected in a sampling based, cross-sectional survey. The Relationship between anthropometric indexes (Hight, Wight, Waist Circumference, Hip Circumference, WHR, WSR, BMI and BF% with cardiovascular risk factors (Tg, Tcho, HDL, and LDL) were determined. For data analysis, statistical significances were assessed by t test and Pearson Correlation. Results: The results of this study showed that in females group there were significant relationships were observed between Tg with wight, WC, WHR and BMI indexes (P 0/05). Furthermore, 26.4% of variance in women's HDL can be explained by changes in their hip circumference. However, in males group there were positive significant correlations between Tcho and height, WHR, WHtR and BF% (P 0/05). Conclusion: Results of this study indicate probably there is overweight and obesity in both genders. Therefore, evaluations and presentation of interventional programs in the lifestyle and raising awareness to control and prevent the problems associated with overweight and obesity are suggested.
medical journal of mashhad university of medical sciences
1735-4013
61
v.
4
no.
2018
1071
1082
https://mjms.mums.ac.ir/article_12207_67ef638d0b2042db03fac0c32c4cbecf.pdf
dx.doi.org/10.22038/mjms.2018.12207
Determining Related Factors to Survival of Colorectal Cancer Patients Using Cox Regression
Samaneh
Sabouri
Department of Epidemiology and Biostatistics, school of health, Mashhad University of Medical Sciences, Mashhad, Iran
author
Habibollah
Esmaily
Department of Epidemiology and Biostatistics, Social Determinants of Health Research center, Mashhad University of Medical Sciences, Mashhad,Iran
author
Soudabeh
Shahid Sales
Associate Professor of Radiation Oncology, Cancer Research Center, Mashhad University of Medical Sciences
author
Mehdi
Emadi
Associate Professor of Statistics, Faculty of Mathematical sciences, Ferdowsi University of Mashhad, Mashhad, Iran
author
text
article
2018
per
Introduction: Colorectal cancer (CRC) is the third common cancer worldwide and its death rate is increasing in Iran. The present study is conducted with the purpose of determining related factors to CRC patients’ survival using Cox regression model. Materials and Methods: In a historical cohort, we examined 404 subjects who were diagnosed with CRC and referred to Omid Hospital in Mashhad from 2006 through 2011. First demographic and clinical information of patients were gathered and then were followed until September 2016. In this paper, Cox regression was utilized to investigate related factors to CRC patients’ survival. For statistical analysis SPSS software was applied and significant level was 0.05. Results: In this research, 217 men (53.7%) and 187 women (46.3%) were studied. The mean±sd of subjects’ age was 56.4±14.7 years and 3- year, 5-year and 7-year survival rates of patients were 0.60, 0.50 and 0.48 respectively. In this study, the median (95% confidence interval) of survival times was calculated 5.48 (3.07, 7.90). According to Cox regression model, BMI (p=0.024), first treatment (p=0.019), stage (p<0.0001) and relapse (p=0.002) were related to patients’ survival. Conclusion: Numerous studies were conducted for survival analysis of CRC patients that they differed in results in some cases. Doing more researches applying other statistical analysis methods is suggested; therefor with identifying related factors to patients’ survival we can contribute suitable medical resources to high risk patients.
medical journal of mashhad university of medical sciences
1735-4013
61
v.
4
no.
2018
1083
1092
https://mjms.mums.ac.ir/article_12202_1b3f8137effd3720cc39b929f69f20d2.pdf
dx.doi.org/10.22038/mjms.2018.12202
Comparison of the effect of Chlorhexidine mouthwash with Green tea(Dine) mouthwash on probable ventilator-associated pneumonia in pediatric intensive care unit
Mohamadreza
Habibzade
Department of Anesthesiology, Isfahan University of Medical Sciences, Isfahan, Iran
author
Amir
Shafa
Department of Anesthesiology, Isfahan University of Medical Sciences,Isfahan,Iran
author
Zahra
Dehghani
Medical Student, Isfahan University of Medical Sciences, Isfahan, Iran
author
text
article
2018
per
Abstract Introduction The use of mouthwashes has recently been effective in reducing ventilator-associated pneumonia in patients admitted to ICU. However, in this study, the effect of chlorhexidine mouthwash with Green tea mouthwash was compared on prevention of ventilator-associated pneumonia in the patients in PICU of Imam Hossein Hospital in 1395-1396. Methods In this clinical trial study, 80 patients admitted to PICU were enrolled according to the study and then the patients were divided into two group under treatment with 0.2% chlorhexidine gluconate and green tea mouthwash. The frequency, time, and manner of mouthwash in both groups were performed in one form three times a day , every eight hours , for 5 days . The incidence of pneumonia and mortality were studied in patients after drug use . Results The incidence of pneumonia was 10% in the chlorhexidine group and 12.5% in the green tea group, so there was no significant difference between two groups based on the incidence of pneumonia (P = 0.72). The results of the treatment in the chlorhexidine group were : 65% complete recovery, 22.5% recovery with complication and 12.5% death, and Green tea were : 57.5% complete recovery, 35% recovery with complication and 7.5% death, and the difference between two groups was not significant (P = 0.43). Conclusion Both chlorhexidine and dine mouthwash can be effective in reducing the incidence of ventilator associated pneumonia and mortality in patients, admitted in ICU.
medical journal of mashhad university of medical sciences
1735-4013
61
v.
4
no.
2018
1093
1099
https://mjms.mums.ac.ir/article_12208_82cae8f6a4a0835a8b0c15c9dcaa1399.pdf
dx.doi.org/10.22038/mjms.2018.12208
The effect of Heart Failure Triage Scale on used resources among heart failure patients with Dyspnea in the emergency department: a randomized clinical trial
Ahmad
Pouyamehr
M.Sc. in Critical Care Nursing, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran
author
Amir
Mirhaghi
Nursing and Midwifery Care Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
author
Ali
Eshraghi
Department of Cardiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
author
Mohammad Davood
Sharifi
Department of Emergency Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
author
text
article
2018
per
Background: It is unclear whether triage scales are able to identify high risk patients with heart failure (HF) or not. The aims of study were to compare the effect of heart failure triage scale (HFTS) and emergency severity index (ESI) on mistriage among patients with heart failure who present to the emergency department (ED). Materials and Methods: A randomized clinical trial was conducted from April to June 2017. 153 HF patients with dyspnea were randomly assigned to HFTS or ESI groups. Triage level and used resources were compared between both groups among HF patients who admitted to coronary care unit (CCU), cardiac unit (CU) and discharged patients from the ED. Content validity was examined using Kappa designating agreement on relevance (k*). Reliability of both scale was evaluated using interobserver agreement (Kappa). Results: Mean age was 62.53 years old. Seventy five and 78 HF patients were assigned to HFTS and ESI groups respectively. Triage level between HFTS and ESI groups was significantly different among patients admitted to CCU (1.0 vs. 2.8), cardiac unit (2.26 vs. 3.06) and discharged patients from the ED (3.53 vs. 2.86). Used resources in HFTS group was significantly different among triage levels (H = 25.89; df = 3; p < 0.001(. Conclusions: HFTS was valid and reliable. HFTS provides a more accurate method for triaging HF patients compared to ESI. It is recommended to make use of HFTS to triage HF patients in the ED.
medical journal of mashhad university of medical sciences
1735-4013
61
v.
4
no.
2018
1100
1111
https://mjms.mums.ac.ir/article_12219_69286c635f9ce22579abfa96d9a99953.pdf
dx.doi.org/10.22038/mjms.2018.12219
Validation of the cardiovascular management self-efficacy scale
Fahimeh
Jafari Sejzi
Department of Psychology, faculty of Human Sciences, University of Zanjan. Zanjan, Iran.
author
Zekrollah
Morovati
Department of Psychology, faculty of Human Sciences, University of Zanjan, Zanjan, Iran.
author
Ramin
Heidari
Department of Cardiovascular, Faculty of Medical, University of Isfahan Medical Sciences, Isfahan, Iran.
author
text
article
2018
per
Introduction: The control of risk factors and lifestyle modification in cardiovascular patients plays an important role and leads to ability of these patients for self-care. Materials and Methods: The aim of this study was to investigate validity and reliability of cardiovascular management self-efficacy scale in Isfahan city. The method of this study was descriptive-correlational. 150 cardiovascular patients were selected using convenience sampling method. The cardiovascular management self-efficacy scale was completed by patients. In order to determine the reliability of the questionnaire, was used of internal consistency method (alpha coefficient) and for verifying validity of exploratory and confirmatory factors analysis. Results: The results showed that alpha coefficient of the whole scale was 0.80 and its sub-scales ranged from 0.57 to 0.97. The results of analysis of main components with the varimax rotation showed that special valued of 3 factors in significant, which totally explains 72.80 of the cardiovascular management self-efficacy variance. The model have confirmed by goodness of fit index indicators. Conclusion: Therefore cardiovascular management self-efficacy scale has a desirable internal consistency and sufficient narrative in the sample of Iranian patients.
medical journal of mashhad university of medical sciences
1735-4013
61
v.
4
no.
2018
1112
1121
https://mjms.mums.ac.ir/article_12220_3546f34ce70bdaaf33ab39d4d1b10e6b.pdf
dx.doi.org/10.22038/mjms.2018.12220
Evaluate the effectiveness of therapy on cognitive emotion regulation spirituality in women with breast cancer
Elaheh
Poorakbaran
Young and Elite Researchers Club, Torbat Heydariyeh Branch, Islamic Azad University, Torbat Heydariyeh, Iran
author
Roghayeh
Mohammadi GhareGhozlou
Ph.D. Student of Psychology, Payame Noor University,Tehran, Iran
author
Seyed Mohamad Reza
Mosavi
Young Researchers and Elite Club, Torbatheydariye Branch, Islamic Azad University,Torbatheydariye, Iran
author
text
article
2018
per
This research that aimed to investigate the effect of group therapeutic spirituality on cognitive regulation of excitement and toleration in women with breast cancer, is a quasi-experimental study that has been done on the basis of pre-test and post-test scheme with the control group. The statistical society of this research was comprised of all the patients with breast cancer who were in Taleghani Hospital of Tehran in 1395. 24 patients were selected out of this society and divided into two groups that each group had 12 members (experimental and control). Then the experimental group was interred to this therapy for 12 weeks, one 60 to 90 minutes session each week. The group therapeutic spirituality that was discussed by Richards and Bergin (2005) was the therapeutic protocol. Both groups were tested using research tools before and after the 12th session of group therapy. Measurement tools included organized clinical interview for I and II and DSM- IV axis disorders, Kumar and Davison toleration questionnaire (CD-RISC, 2003) and excitement cognitive regulation questionnaire (CER). The multivariate and one-way covariance method was used to analyze the collected data. The results showed that the spiritual therapy group was caused to increase of excitement cognitive regulation in the experimental group. Among excitement cognitive regulation components, self-blame, rumination, catastrophizing and blaming others were reduced in the experimental group and acceptance, positive refocusing, refocus on planning, positive reappraisal and view making was increased in the experimental group.
medical journal of mashhad university of medical sciences
1735-4013
61
v.
4
no.
2018
1122
1136
https://mjms.mums.ac.ir/article_12223_9dfceacfdfa62c5ad8454e5c6e482c89.pdf
dx.doi.org/10.22038/mjms.2018.12223
Stem cell therapy and the Central nervous system diseases: findings, obstacles, and future
Leila
Gholami
- Nanotechnology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
author
Elahe
Mahdipour
Department of Medical Biotechnology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
author
text
article
2018
per
Some neurological diseases such as parkinson, stroke, and spinal injury are as a result of cellular loss in the otherwise normal nervous system. Replacing damaged cells with healthy ones has opened a new hope window to treat or prevent the further disease progression. Different studies have shown that stem cells can differentiate and replace the lost neurons and glial cells in the central nervous system. However, the right cell type selection, treatment procedure, the best cell delivery method, and the treatment follow-up are among the major challenges faced this therapeutic vision. In this review, we have got through significant basic and clinical studies for neurological disease cell therapy to provide a basis for future applications of this therapeutic approach in clinics. Indeed, continuous and noticeable progress in cell therapy through the basic and clinical investigations will offer new hopes to people suffer from these diseases across the globe.
medical journal of mashhad university of medical sciences
1735-4013
61
v.
4
no.
2018
1137
1162
https://mjms.mums.ac.ir/article_12235_30beaa0fdd2f339f45a0a7de4dfeadc6.pdf
dx.doi.org/10.22038/mjms.2018.12235
Molecular Signaling Pathways involved in Temporal Lobe Epilepsy
Parastoo
Morteza-zadeh
Shefa Neuroscience Research Center, Khatam Alanbia Hospital, Tehran, Iran.
author
Ali
Jahanbazi
Department of Clinical Biochemistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
author
Maryam
Borhani-Haghighi
Department of Anatomy, Tehran University of Medical Sciences, Tehran, Iran.
author
Sajad
Sahab Negah
Department of Neuroscience, Mashhad University of Medical Science, Mashhad, Iran
author
text
article
2018
per
Epilepsy is a chronic neurological disorder that defined as a disorder of recurrent seizures and characterized by an imbalance of excitation and inhibition in the brain. Despite many efforts in recent years, one-third of the epileptic patients are refractory to medical treatment. It has been reported that genetic factors, synaptic ion channels, excitatory and inhibitory neurotransmitters and activation of various receptors such as ionotropic and metabotropic glutamate receptors in the central nervous system can promote epileptogenesis. Further research to investigate the molecular mechanisms and ions involved in the development of epilepsy is needed. In this review, we present an overview of current status into the molecular signaling pathways involved in epileptogenesis. Furthermore, we will focus on temporal lobe epilepsy (TLE) molecular mechanisms. Understanding of molecular mechanisms could provide new fascinating insights into drug target identification in the prevention of epileptogenesis.
medical journal of mashhad university of medical sciences
1735-4013
61
v.
4
no.
2018
1143
1153
https://mjms.mums.ac.ir/article_12703_d41d8cd98f00b204e9800998ecf8427e.pdf
dx.doi.org/10.22038/mjms.2018.12703