Comparison of Left Ventricular Ejection Fraction and Ventricular Volume in Echocardiography and Nuclear Myocardial Perfusion Scan
S.H
Danesh
دانشیار
author
R.
Zakavi
دانشیار
author
S
Afzalnia
دستیار تخصصی قلب و عروق
author
M
Taherpour
متخصص قلب و عروق – گروه قلب بیمارستان امام رضا مشهد
author
M
Abbaszadeh
متخصص قلب و عروق – گروه قلب بیمارستان امام رضا مشهد
author
text
article
2007
per
I ntroduction: Radionuclide scanning of the heart has incremental value in diagnosis and risk stratification of coronary artery disease. Gated myocardial perfusion SPECT is a new method and the state of the art in coronary artery disease detection. This study was done to evaluate estimation of LV volume, wall motion diameters and ejection fraction by gated myocardial perfusion scan and make a comparison with trans thoracic echocardiography. Material and Methods: In this cross-sectional descriptive study during Sep 2001- Dec 2002, 68 patients suspected of IHD who were referred to nuclear Medicine Department of Imam Reza Hospital in Mashhad University of Medical Sciences were under taken gated myocardial perfusion SPECT, and then referred to echocardiography unit for trans thoracic echocardiography. LV volume, ejection fraction, regional wall motion in different views of 2D-echo was recorded and the results were compared by descriptive statistics. Results:This study was performed on 68 patients. The mean age of patients was 52.8 (min: 38, Max: 75). 54% of patients were male and 46% were female. Mean end systolic volumes of LV was 32.4ml (sd: 37.1) estimated by echocardiography and 68.3ml (sd: 52.2) stimated by radionuclide scan (pv: 0.00). Mean end diastolic volume of LV was 129.6ml (sd: 45.8) in echocardiography and 143.7ml (sd: 46.23) in radionuclide scanning (pv: 0.00). Mean ejection fraction value of LV was 54.6 (sd: 12.44) estimated by echocardiography and 54 (sd: 12.94) by radionuclide scan (pv: 0.00). Conclusions: Left ventricular end systolic and diastolic volumes and ejection fraction, obtained by gated myocardial perfusion scan and echocardiography, had significant statistic correlations and estimation of LV wall motions and ejection fraction by gated SPECT was as echocardiography.
medical journal of mashhad university of medical sciences
دانشگاه علوم پزشکی مشهد
1735-4013
50
v.
1
no.
2007
5
10
https://mjms.mums.ac.ir/article_5586_bd072270981b6b4a5d7e3db7f7f15155.pdf
dx.doi.org/10.22038/mjms.2007.5586
Factors Affecting the Hospitalization Period of Kidney Transplantation Recipients
F
Nazemian
استادیار فوق تخصص داخلی (کلیه)
author
M
Naghibi
استاد داخلی (کلیه)
author
O
Naghibi
پزشک عمومی
author
text
article
2007
per
Introduction: Nowadays, as many of the problems confronting kidney transplantation have been solved, the number of operations has increased dramatically. So, resource utilization and financial issues have been cited as a new problem for transplantation centres. This study was done to find and assess the factors which can reduce the hospitalization period, while this factor claims the biggest share of the total cost of the treatment process. Material and Methods: In this retrospective study, done in kidney transplantation word of Imam Reza Hospital, the medical history of 170 kidney transplantation recipients and donors, whose operations were performed between 2000 and 2002, were studied. Collected information of recipient’s characteristics included gender, age, reason for kidney failure, weight, height, blood group, dialysis period, transplantation history, immunosuppressant regimes, complications after operation, and hospitalization after the first discharge due to transplantation operation complications; and for the donors, age, sex and blood group of the donor and the type of donor (cadaver or living) and the relationship between the recipients and the donors were gathered in a questionnaire and analyzed by descriptive statistics and T – test. Results: A mong all pre-transplant variables only length of dialysis before transplantation and the relationship between donors and recipients were found to be independently significant in predicting the increased hospitalization period and consequently charges. Conclusion: It is shown that by reducing the waiting time and performing more operations on relative donors and recipients, we can significantly decrease hospitalization period and as a result the cost of treatment.
medical journal of mashhad university of medical sciences
دانشگاه علوم پزشکی مشهد
1735-4013
50
v.
1
no.
2007
11
16
https://mjms.mums.ac.ir/article_5587_430ef1ad1dd4cfe2465021adf087db75.pdf
dx.doi.org/10.22038/mjms.2007.5587
The Role of Laparoscopy for Management of Nonpalpable Testis (NPT)
A
Shamsa
استاد ارولوژی
author
M.J
Parizadeh
دانشیار گروه اطفال
author
S
Smailnia
دستیار ارولوژی
author
M.R
Teymouri
دستیار ارولوژی
author
text
article
2007
per
I ntroduction: Undescended testes is seen in 3.4% male neonates and 20% of these testes are nonpalpable. This study was done to evaluate the diagnositic and therapeutic effects of laparoscopy in chidren and young adults nonpapable testes. Material and Methods: This descriptive study was done in Urology Depantment of Ghaem Hospital. 15 patients aged 9 months to 31 years and 19 Testes were studied. Through a 5 or 10 mm incision above umbilicus, 5 or 10 mm Hasson trocar was inserted under vision. 5 or 10 mm telescope was used to see whether the testis was present or not. If not, the operation was ended. Otherwise, the process followed by standard orchidopexy or laparoscopic orchidopexyorlaparoscopic orchidectomy. Results: 2 cases did not have testis (19 & 3 years), 9 cases had unilateral NPT (7 rights, 2 left); three bilateral, and the last one, a case of testicular feminization with karyotype of 46 XY and cheif complaint of amenorrhea. 4 cases had standard orchidopexy and in the last three, one stage laparoscopic orchidopexy was done. In the testicular feminization case laparoscopic orchidectomy. All testes brought into the subdartus fascia, they remaind in the scrotume without athrophy. Conclusion: Laparoscopy is the best tool for diagnosis of non palpable testis. Laparoscopic orchidectomy is also the choice treatment for testicular feminization. Laparoscopic orchidopexy is feasible and can be a duplicate of open orchidopexy.
medical journal of mashhad university of medical sciences
دانشگاه علوم پزشکی مشهد
1735-4013
50
v.
1
no.
2007
17
22
https://mjms.mums.ac.ir/article_5588_75cd5e0624d6dca4e7798e5c966941f2.pdf
dx.doi.org/10.22038/mjms.2007.5588
Evaluation of Diagnostic Value of Fine Needle Aspiration In Thyroid Nodules
S
Mirsadraee
استاد پاتولوژی
author
Z
Mousavi
دانشیار آندوکرینولوژی
author
M
Farzadnia
استادیار پاتولوژی
author
A
Bavafa
پزشک عمومی
author
S
Kakhi
دانشجوی پزشکی
author
text
article
2007
per
ntroduction: Thyroid diseases particularly nodular lesions are among the most common diseases of human. Approximately 5% of the populations have palpable thyroid nodules which are detected in the routine Autopsy. Nearly 95% of thyroid nodules are benign wherease malignant nodules include 5% of them. Fine needle aspiration (FNA) has been recognized as a simple, inexpensive and available procedure for rapid diagnosis. The objective of this study was to determine the value of FNA in thyroid diagnosis. Material and Methods: In this retrospective research, 536 patients with thyroid nodules reffered for FNA or hospitalized for thyroid surgery in Imam Reza Hospital from March 2002 until March 2005 were studied. Individual and laboratory data were gathered in a questionnaire and analyzed by descriptive statistics. Results: This study included 107 men and 429 women and the average age of patients was 40 years. Out of 536 patients 12.7% had malignant, 70.3% benign and 8.6% yield suspicious results and 2.4% of FNAs were insufficient. Comparing the results of FNA and biopsy, FNA had the specificity of 89.5%, sensitivity of 91.5%, and accuracy of 93.7%; negative and positive predictive values were 80.9% and 95.5% respectively. Conclusion:These results reemphasized that, FNA is a simple and non invasive procedure and if performed carefully and evaluated by an expert pathologist is of high sensitivity and specificity.
medical journal of mashhad university of medical sciences
دانشگاه علوم پزشکی مشهد
1735-4013
50
v.
1
no.
2007
23
30
https://mjms.mums.ac.ir/article_5589_7c2e0939bd25bb2a7b50fd426679dd4b.pdf
dx.doi.org/10.22038/mjms.2007.5589
Surgical Ttreatment of Chest Wall Tumours
H
Fatahi
دانشیار گروه جراحی قلب و توراکس
author
S.R
Sharifi
استادیار گروه ارتوپدی بیمارستان شهید کامیاب
author
B
Rahim
رئیس بخش جراحی توراکس بیمارستان ولیعصر دانشگاه علوم پزشکی تهران
author
M.H
Amouzgar
استادیار جراحی عمومی
author
F.
Samini
استادیار جراحی مغزو اعصاب دانشگاه علوم پزشکی مشهد
author
H
Etemad Rezaee
استادیار جراحی مغزو اعصاب دانشگاه علوم پزشکی مشهد
author
text
article
2007
per
Introduction: Chest wall tumor is an uncommon malignancy; and incomplete diagnosis and resection and inability to reconstruction of expanded chest wall defect after resection, Causes mortality and morbidity in patients. Academic surgery provides the best choice for the patients, and surgery technique should be based on the individual characteristics. This study was done to evaluate the surgery results of chest wall tumors and to report the operated cases. Material and Methodes: The descriptive research was performed in Tehran Valiasr Hospital and Ghaem Hospital (Mashhad University of Medical Sciences) from 1995 to 2003 (9 years) and 61 patients have been evaluated in retrospective study. Individual, clinical, laboratory, treatment and complication data were gathered in a questionnaire and analyzed by descriptive statistics. Resultes: 28 (45.9%) patients had primary chest wall malignancy, 4 (6.55%) patients had metastatic tumors, 10 (16.39%) patients had benign tumors, 16 (26.22%) patients had inflammatory disease and 3 (4.9%) had undiagnosed pattern. Conclusion: Results of our study and also review of other articles recommended that wide enblock exiscion of chest wall tumors with appropriate reconstruction is the best method of treatment.
medical journal of mashhad university of medical sciences
دانشگاه علوم پزشکی مشهد
1735-4013
50
v.
1
no.
2007
31
42
https://mjms.mums.ac.ir/article_5590_592ea16f818cd584e384a116c5b97e78.pdf
dx.doi.org/10.22038/mjms.2007.5590
The Correlation between Helicobacter pylori Infection and Serum Ferritin Concentration and Iron Deficiency Anemia
M.R
Keramati
استادیار گروه خون شناسی و بانک خون
author
M
Mahmoudi
دانشیار گروه ایمونولوژی
author
F
Samiei
کارشناس آزمایشگاه ایمونولوژی
author
text
article
2007
per
Introduction: Iron deficiency is the most common cause of anemia worldwide, however a significant number of these patients remain undiagnosed. Based on the high frequency of iron deficiency anemia and H. pylori infection in Iran, This study was done to evaluate their correlation. Material and Methods: This descriptive study was done in Imam Reza Hospital in the year 2005. 184 patients mostly with GI system complaints were referred for determination of serum antiH.pylori IgG and IgA levels. In addition, we performed complete cell blood count and serum ferritin concentration tests for all the patients. Individual, cell blood count and serum ferritin concentration data were gathered in a questionnaire. Statistical analysis was performed by SPSS softwere and descriptive statistics. Results: Our results showed that in 77.8% of our patients at least one of serum anti H. pylori IgG or IgA antibodies were positive. The rate of positive serology was increased in higher age groups. Patients’ gender did not influence the results. Serum ferritin level did not show any correlation with H. pylori infection and the frequency of iron deficiency anemia was not higher in infected individuals. Conclusions: Although many studies have shown positive correlation between H. pylori infection and iron deficiency anemia, few studies have not confirmed these findings. Our study does not support this correlation, as well. Due to high frequency of both iron deficiency anemia and H. pylori infection in Iran, further large scale studies are recommended.
medical journal of mashhad university of medical sciences
دانشگاه علوم پزشکی مشهد
1735-4013
50
v.
1
no.
2007
43
48
https://mjms.mums.ac.ir/article_5591_0a0155114165ad76bfb740702de6667f.pdf
dx.doi.org/10.22038/mjms.2007.5591
Value of Urine Analysis in Diagnosis of Urinary Tract Infection in Children
M
Jafarzade
دانشیار کودکان
author
S.A
Jafari
استادیار کودکان
author
text
article
2007
per
Introduction:Because of high prevalence and morbidity of UTI in children, early diagnosis and on time treatment are essential; but confirmation of UTI diagnosis needs a urine culture which takes at least 48 hours. The aim of this study was to ascertain predictive values of urinalysis in the diagnosis of UTI. Material and Methods:In this descriptive study the recorded files of 59 febrile patients, 30 patients with positive urine culture and 29 patients with negative urine culture, hospitalized in Imam Reza Hospital from 2003 to 2004, were evaluated. Age, sex, results of U/A including pyuria, hematuria, urine nitrite test and urine culture were gathered and analyzed using descriptive statistics. Results: In this study sensitivity and specificity of nitrite test in diagnosis of UTI were 46.7% and 89.7% respectively. Sensitivity and specificity of pyuria were 76.7% and 48.3% respectively.Sensitivity and specificity of U/A in diagnosis of UTI in children under 2 years old were 85 % and 70 %, but in patients older than 2 years old were 100% and 35% respectively. Conclusion:This study indicated that non active U/A in children older than 2 years old rules out UTI in nearly 100% of cases.
medical journal of mashhad university of medical sciences
دانشگاه علوم پزشکی مشهد
1735-4013
50
v.
1
no.
2007
49
52
https://mjms.mums.ac.ir/article_5592_7f4816fed155afa88e41f80ea408eb80.pdf
dx.doi.org/10.22038/mjms.2007.5592
The Eeffect of Laterally Elevated Wedged Insoles in Comparison with Neutrally Wedged
Insoles on the Symptoms of Patients with Medial Knee Osteoarthritis
M.R
Hatef
دانشیار، فوق تخصص روماتولوژی
author
Z
Mirfeizi
استادیار، فوق تخصص روماتولوژی
author
M.H
Joukar
استادیار، فوق تخصص روماتولوژی
author
M.
Mirheydari
پزشک عمومی - بیمارستان امام رضا (ع)
author
text
article
2007
per
Introduction: Knee osteoarthritis is a common condition having an increased prevalence with age. Non-pharmacological interventions are frequently and widely used and strongly recommended in the management of patients with osteoarthritis. Lateral-wedged insoles have been shown to help clinical pain associated with medial compartment osteoarthritis. Yet, it has been shown ineffective in some studies. This study was done to compare the effect of laterally elevated wedged insoles with neutrally wedged insole an the symptom of patients with medial knee osteoarthritis. Material and Methods: This double – blind clinical – trial study was done in Rheumatology ward of Imam Reza Hospital in the years 2004 – 2005. 118 patients were randomly drivided into 2 groups. Case group (57 patients) received laterally wedged insoles and control group (61 patients) received neutrally wedged insoles for two months. Edinburg knee functional scale was used. At the end of month 2, Patients were asked about the severity of knee pain within the last 2 days and the amount of anti-inflammatory drugs taking within the 2 weeks ago and another Edinburg knee functional scale completed. Analysis of data was performed with SPSS version 11.5. The results were compared by using student’s t test, chi-square and Mann Whitney tests. Results: Of the 150 patients enrolled, 118 (49 famel and 8 male in laterally wedged insole group and 52 famel and 9 male in neutrally wedged insole group) completed the study. There was good baseline balance between the groups, in respect of self reported knee pain, Edinburg knee functional scale and anti-inflammatory drugs taking by the patients. At the end of the study there was statistically significant difference in severity of knee pain in each of the groups from baseline. (pConclusion: Laterally elevated wedged insole was shown to be more effective in reduction of symptoms in osteoarthritic patients.
medical journal of mashhad university of medical sciences
دانشگاه علوم پزشکی مشهد
1735-4013
50
v.
1
no.
2007
53
60
https://mjms.mums.ac.ir/article_5593_276df199b47a000f1cdb493c5f7423f2.pdf
dx.doi.org/10.22038/mjms.2007.5593
Effect of Hyperthyroidism on Bone Mineral Density in Premenopausal Women
p.
Layegh
استادیار غدد مترشحه داخلی
author
R.B.
Abotorabi
دانشیار غدد مترشحه داخلی
author
R
Rajabian
استاد غدد مترشحه داخلی
author
M
Khajedaloee
استادیار پزشکی اجتماعی
author
Z.
Mousavi
دانشیار غدد مترشحه داخلی
author
text
article
2007
per
Introduction: Hyperthyroidism is a state of high bone turnover, but there is controversy about its effects on bone mineral density. It is more common in females (F: M ratio 10:1). Since post-menopausal women are potentially at risk for osteoporosis because of aging and estrogen deficiency and because hyperthyroidism is more common in females, this study was done to determine the effects of hyperthyroidism on bone mineral density (BMD) in premenopausal thyrotoxic women. Material and Methodes: In this case- control study 50 women with untreated hyperthyroidism (age- range 20-50 yr) from outpatient endocrine clinics in the years 2004 – 2005 were selected. Patients who used drugs or had diseases that affect bone mineral density were excluded. After history taking and physical examination, thyroid function tests, PTH, phosphorus, calcium, alkalin phosphatase, fasting plasma glucose and creatinine were measured and then bone densitometry by LUNAR (DPX-IQ) device was performed. One hundred and ten age- and weight – matched healthy women from participants in Iranian Multicenter Osteoporosis Study (IMOS) were selected as controls. SPSS version 11.5 was used for data analysis and P value less than 0.05 cosidered as significant. Results: Mean of age, height and weight was similar in patients and controls. Forty seven cases (94%) had Graves’ disease and 3 cases (6%) had toxic solitary adenoma. Mean duration of disease before diagnosis was 6.02±4.38 months. There was no significant difference in mean of bone mineral density in vertebral column (p=0.83) and also in femural neck (p=0.74) between patients and controls. There was no correlation between bone mineral density in vertebral column and also in femural neck with serum levels of T4, T3, TSH and FT4I. There was no correlation between bone mineral density and duration of disease before diagnosis and also between bone mineral density and age. Conclusion: Hyperthyroidism is a known state of high bone turnover, but in hyperthyroid premenopausal women with disease of short duration and without other risk factors of low bone mass, bone densitometry could not be recommended as a required routine measurement.
medical journal of mashhad university of medical sciences
دانشگاه علوم پزشکی مشهد
1735-4013
50
v.
1
no.
2007
61
66
https://mjms.mums.ac.ir/article_5594_d541b877ad050f261a7a719e7ceee509.pdf
dx.doi.org/10.22038/mjms.2007.5594
Usage of Ortolani and Barlow Tests in Diagnosis of Dislocation Displasia of the Hip
A.R
Reyhani
متخصص ارتوپدی بیمارستان شهید مصطفی خمینی
author
D
Mahdibarzi
متخصص ارتوپدی بیمارستان شهید مصطفی خمینی
author
Gh.
Faal
متخصص اطفال بیمارستان دکتر شیخ
author
Sh.
Aghaee
کارشناس مامائی
author
text
article
2007
per
Introduction: Dislocation displasia of the hip (DDH) is one of the most common congenital deformities and early physical examination is the best method for diagnosis. Ortolani and Barlow are two famous tests suggested by almost all of text books and researche for early diagnosis of DDH. This study was done to evaluate their usage in neonatal physical examination. Material and Methods: This descriptive study was done in labor wards and Neonatal wards of Mashhad Medical University Centers. 184 neonates in center A and 229 neonates in center B were studied. Midwifery students were taught about clinical examination and Ortolani and Barlo tests. They divided in to two groups and their 3 – month attempt in this field was observed. Data was gathered in a questionnaire and analyzed by SPSS, descriptive statistics and frequency distribution tables. Result: Evaluation of 235 neonates who were born in two hospitals of Mashhad University (A center = 131, B center = 104) showed that only 0.85% of neonates have been evaluated by gynecologist, and 23.6% by podiatrist. 24.26% of neonates were out of controls that were not used in the study. Conclusion: This study showed the danger alarm of increasing risk for neglected DDH. Teaching, and emphasizing on performance of these two tests can decrease handicapped population rate, cost of treatment and rehabilitation.
medical journal of mashhad university of medical sciences
دانشگاه علوم پزشکی مشهد
1735-4013
50
v.
1
no.
2007
67
70
https://mjms.mums.ac.ir/article_5595_5388f16e1e5cb621fc20616ce8eb3cf6.pdf
dx.doi.org/10.22038/mjms.2007.5595
Succinylcholine-Induced Fasciculation Prevention, with Lidocaine
M
Taghavi
استادیار بیهوشی
author
M
Razavi
متخصص بیهوشی
author
H
Yavari
کارشناس پرستاری (بیهوشی) - بیمارستان امام رضا (ع)
author
text
article
2007
per
Introduction: Succinylcholine is a depolarizing muscular relaxant with rapid onset and short-acting effect. It is of considerable usage in emergency conditions and short - term surgeries; but has several side effects, a great deal of which will be reduced by prevention of fasciculation. Material and Methodes:This clinical – trial stady was done in the year 2006 In Ear, Nose, Throat department of Imam Reza Hospital.40 patients with ASA Ι and ENT operations categorized randomly into two similar groups. Control group recieved sufentanyl 0.2 mg/kg, propofol 2.5 µg/kg and succinylcholine 1.5 mg/kg. In case group lidocaine 1mg/kg and after 1 min succinycholine was administered. Incidence and severity of fasciculation and quality of intubation were evaluated. Data was analyzed by descriptive statistics, T – test, χ – square, valis, and χ2. Results:Demographic parameters were not different significantly according χ2 test. There was significant difference regarding the incidence of fasciculation but there was no significant difference with respect to the intensity of fasciculation and quality of intubation. Conclusion: This study showed that lidocaine 1mg/kg before induction decreases succinylcholine-induced fasciculation.
medical journal of mashhad university of medical sciences
دانشگاه علوم پزشکی مشهد
1735-4013
50
v.
1
no.
2007
71
74
https://mjms.mums.ac.ir/article_5596_c04e6ac21127f3918e6b39ed7be6a48d.pdf
dx.doi.org/10.22038/mjms.2007.5596
Cigarette Smoking and Its Relationship with Pulmonary Tuberculosis
F.
Rezaee
استادیار
author
H.
Akbari
متخصص داخلی
author
H
Rezaee
دانشجوی پزشکی
author
text
article
2007
per
Introduction: Pulmonary tuberculosis is one of the most known human diseases and has a long history. Regarding the fact that its prevalence among Iranians is relatively high, several programs have been designed in order to control this disease. The objective of this study was to determine wether there is any relationship between pulmonary tuberculosis and cigarette smoking as an independent risk factor. Material and Methods:This study was a case control survey done in Pulmonary Ward of Imam Reza Hospital from January 2003 to March 2006. 64 males with tuberculosis were compared with 64 non – tuberculotic males in the same range of age. Data was gathered with a direct questionnaire and analyzed with SPSS software. Results:The results derived from this study indicated that the percentage of smokers was 59.4% in the case group who had pulmonary tuberculosis; while it turned to be 37.5% in the control group. These was a significant difference between two groups in smoking duration, number of cigarretes smoked per day and the age about which the smokers started smoking. Conclusion:The study showed that smoking is an independent risk factor for pulmonary tuberculosis infection. Regarding other studies that revealed the role of cigarette smoking in suppressing the immune system, it is highly advised to design effective programs for cigarette quitting to reduce the rate of tuberculosis in the society.
medical journal of mashhad university of medical sciences
دانشگاه علوم پزشکی مشهد
1735-4013
50
v.
1
no.
2007
75
80
https://mjms.mums.ac.ir/article_5597_b2880ab845e51b770976b4969724db83.pdf
dx.doi.org/10.22038/mjms.2007.5597
Brain Computed Tomography Scan Nessecity before Lumbar Puncture in Meningitis Patients with More than 60 Years Age
M.R.
Taghavi
دستیار بیماریهای عفونی
author
A.A
Heydari
استادیار بیماریهای عفونی
author
J.
Hashemi
دانشیار رادیولوژی بیمارستان امام رضا (ع)
author
text
article
2007
per
Introduction: Central Nervous System (CNS) infections especially meningitis is a medical emergency that once suspected should be proved through Lumbar Puncture (LP) and cerebrospinal Fluid (CSF) analysis. On the other hand due to life – threatening complications such as brain herniation in the people older than 60, the procedure safety is debated. This study was done in order to determine the necessity of the Lumbar Puncture (LP) in the patients older than 60 years old who are suspected to meningitis. Material and Methodes: This descriptive study was done in Infectious Clinic of Imam Reza Hospital, Mashad, Iran from fall 2003 to fall 2005. 90 patients who were suspected to meningitis and undergone brain CT scanning and LP were studied. The results of patient's history, physical examination, demographic information, CT scanning and LP all collected in a questionnaire and analyzed by spss and statistics examinations. Results: Among 90 patients suspected of meningitis who underwent Brain CT-scan and LP, 81 suffered from loss of consciousness, 2 were chronic course and 7 without clinical LP contraindication other than age. 75 had normal CT-scan and 15 had abnormal CT-scan, amongwhich was no space occupying lesion with mass effect or midline shift. Final diagnosis was acute bacterial meningitis in 14 cases and aseptic meningitis in 7 cases and other causes of meningitis in 7 cases, Encephalitis in 1, and 61 cases other CNS infection. Conclusion: Despite other clinical contraindications for LP in most of the patients, in 75 cases (83 %) brain CT-scan was normal and in only 15 cases (17%) there was abnormal CT-scan amongwhich none was a contraindication for LP (i.e space occupying lesion with mass effect or midline shift). Therefore the role of «age over sixty» as an absolute indication for Brain CT-scan, regarding the existing medical facilities and conditions in our country, did not seem acceptable.
medical journal of mashhad university of medical sciences
دانشگاه علوم پزشکی مشهد
1735-4013
50
v.
1
no.
2007
81
88
https://mjms.mums.ac.ir/article_5598_f9e400b01e5ba2d7b0db50a1f64487f2.pdf
dx.doi.org/10.22038/mjms.2007.5598
Evaluation of Susceptibility of Conventional Anti Fungal Drugs with Flow Cytometry Technique
M.J
Najafzade
مربی گروه انگل شناسی و قارچ شناسی دانشگاه علوم پزشکی مشهد،
author
M
Falahati
استادیار گروه انگل شناسی و قارچ شناسی دانشگاه علوم پزشکی ایران
author
L.
Akhlaghi
استادیار گروه انگل شناسی و قارچ شناسی دانشگاه علوم پزشکی ایران
author
K.
Poshangbagheri
دانشجوی دکترای میکروبیولوزی دانشگاه علوم پزشکی اصفهان
author
text
article
2007
per
Introduction: During the last decades, the incidence of fungal infection has been increased in many countries. Because of the increasing resistantce to antifungal agents, determination of an efficient strategic plan for treatment of fungal diseases is an important issue in clinical mycology. Material and Methods:Many methods have been introduced and developed to determine invitro susceptibility tests. During the recent years, flow cytometry has been developed to solve the problem, and many papers have documented the usefulness of this technique. This study was done to evaluate the invitro susceptibility of standard PTCC strain and some clinical isolates of Candidaevaluated by macrodilution broth method according to NCCLS guidelines and flow cytometry susceptibility test. This descriptive study was done in Iran Medical University. Clinical isolates of Candidawere treated by Amphotericin B, Clotrimazole, Fluconazol, Ketoconazol and miconazole and then evaluated by flow cytometry and microdilution. Data was gathered in a questionnaire and analyzed by descriptive statistics. Results:The data indicated that macrodilution broth methods and flow cytometry have the same results in determination of MIC for amphotericinB, clotrimazole, fluconazole, ketoconazole and miconazole in Candida albicans PTCC5027 as well as clinical candida isolate, such as C.albicans, C.kefyr, C.glabrata, C.parapsilosis and C.dubliniensis. Conclusion:Comparing the result obtained by macrodilution broth and flow cytometry methods revealed that flow cytometry was more convenient and faster than broth methods. It is suggested that flow cytometry susceptibility test can be used as a powerful tool in determination of MIC and administration of the best antifungal drug in treatment of patients with Candida infections especially systemic candidiasis.
medical journal of mashhad university of medical sciences
دانشگاه علوم پزشکی مشهد
1735-4013
50
v.
1
no.
2007
89
94
https://mjms.mums.ac.ir/article_5599_a9c2db87cda2e5cfe0f9f93b708a9ac2.pdf
dx.doi.org/10.22038/mjms.2007.5599
Abetalipoproteinemia: Report of Two Cases
HR.
Kianifar
استادیار و فوق تخصص گوارش اطفال
author
N.
Zabolinejad
استادیار پاتولوژی، رزیدنت پاتولوژی
author
F
Heidari
سایر
author
text
article
2007
per
Introduction: Abetalipoproteinemia is a rare disorder of lipoprotein metabolism, which causes low levels of cholesterol and absence or very low levels of LDL and VLDL. This rare autosomal recessive disorder is characterized by lipid malabsorption, spinocerebellar degeneration, acanthocytosis and retinopathy. In this study two cases of this disorder presented with severe malabsorption and abdominal distention, which mimicked celiac and fibrocystic diseases were reported.
medical journal of mashhad university of medical sciences
دانشگاه علوم پزشکی مشهد
1735-4013
50
v.
1
no.
2007
96
100
https://mjms.mums.ac.ir/article_5600_759073713be42e032aa344c808dcabf8.pdf
dx.doi.org/10.22038/mjms.2007.5600
Use of the Internal Thoracic Artery as a Suitable Conduit for Systemic-Pulmonary Shunt; a case report
K.
Alizade
دستیار جراحی قلب
author
A
Sadeghpoor
استادیار گروه جراحی قلب
author
K
Alizadeh
دستیار قلب و عروق - دانشگاه علوم پزشکی و خدمات بهداشتی درمانی ایران،بیمارستان قلب شهید رجایی
author
text
article
2007
per
Introduction: There are a number of systemic-to-pulmonary artery shunts being performed by various surgeons. Currently the most widely used systemic-pulmonary shunt is the modified Blalock-Tausig shunt. This shunt is highly effective even in neonates with small pulmonary arteries. The case of a 15-year-old girl in whom the internal thoracic artery was used to create a systemic-pulmonary artery shunt after the failure of a previous Blalock-Tausig shunt is reported. This was the first report of such a case in which the internal mammary artery was used to establish systemic to pulmonary arterial flow in Iran.
medical journal of mashhad university of medical sciences
دانشگاه علوم پزشکی مشهد
1735-4013
50
v.
1
no.
2007
101
104
https://mjms.mums.ac.ir/article_5601_4658d5404871fa99a2f22168dfa48954.pdf
dx.doi.org/10.22038/mjms.2007.5601
Sinus Histiocytosis with Massive Lymphadenopathy (Rosai-Dorfman Disease):
A Case Report
N
Zabolinejad
استادیار پاتولوژی
author
M.
Hiradfar
استادیار جراحی اطفال
author
Z
Badiee
استادیار اطفال
author
N
Ghaemi
استادیار اطفال
author
A.
Attaranzadeh
رزیدنت پاتولوژی
author
text
article
2007
per
Introduction: Sinus histiocytosis with massive lymphadenopathy (SHML) or Rosai-Dorfman disease (RDD) is a rare benign histiocytic disease of unknown etiology, usually associated with lymph node enlargement in various superficial or deep sites. It usually shows a prolonged clinical course with occasional exacerbation and remission phases. In this article case of RDD in a 5-year-old male with large right inguinal and bilateral cervical lymphadenopathies were, occasional fever and anemia was described. The clinical presentation, histopathologic characteristics, and treatments of RDD were discussed.
medical journal of mashhad university of medical sciences
دانشگاه علوم پزشکی مشهد
1735-4013
50
v.
1
no.
2007
105
109
https://mjms.mums.ac.ir/article_5602_de62f6b4dca66bf711f145764679fa52.pdf
dx.doi.org/10.22038/mjms.2007.5602