ORIGINAL_ARTICLE
The relationship between plasma lipoprotein (a) level and major cardiovascular risk factors in patients with type2 diabetes mellitus
Introduction: Lipoprotein a is a risk factor for coronary artery disease. Although many studies have been conducted in the non-diabetic population that shows the role of increasing plasma Lp (a) concentration and atherosclerotic disease, this role is not clear in the diabetic population. Therefore, the aim of this study was to determine the relationship between plasma lipoprotein levels and cardiovascular risk factors in patients with type 2 diabetes. Subjects & Methods: This study was performed in the diabetic clinic of Imam Khomeini Hospital in Tehran ,from 2005 to 2007. A total of 346 patients were selected from 600 patients with type 2 diabetes. To measure the association of high levels of Lp (a) and cardiovascular risk factors, patients were divided into two groups of normal Lp (a) (< 35mg / dl) levels and elevated levels of Lp (a) (> 35mg / dl) and risk factors between the two groups were compared by statistical tests. Results: Our results showed that there was a positive and significant correlation between Lp (a) and total cholesterol (r=0.217, P<0.001), HDL (r=0.141, P=0.008), LDL-C (r=0.241, P<0.001), apolipoprotein B (r=0.220, P<0.001) and Framingham Scoring System (FSS) (r=0.135, P=0.135) in patients. Mean cholesterol, LDL, HDL, apolipoprotein B and FSS levels were significantly higher in patients with Lp (a) ≥35mg /dl than those with normal Lp (a) level (Conclusion: Serum levels of Lp (a) have a significant positive correlation with lipid variables (other than triglyceride) and higher levels than 35mg /dl with increased risk factors for cardiovascular disease in diabetic patients.
https://mjms.mums.ac.ir/article_10771_e9b7af8d80f1e55531e375dd0d74c663.pdf
2018-01-21
727
733
10.22038/mjms.2018.10771
Coronary artery disease risk factors
Lipoprotein a
Myocardial infarction
diabetes type2
Hooman
Bahrami-Motlagh
hoomanbahrami@gmail.com
1
radiologist,Shahid Beheshti University Of Medical Science,Tehran,Iran
AUTHOR
Manouchehr
Nakhjavani
nakhjavanim@tums.ac.ir
2
Endocrinology And Metabolism Research Center,Tehran University Of Medical Science,Tehran,Iran
AUTHOR
Fatemeh
Esfahanian
fesfahanian@tums.ac.ir
3
Endocrinology And Metabolism Research Center,Tehran University Of Medical Science,Tehran,Iran
AUTHOR
Mohammad ali
Yaghoubi
yaqubima@yahoo.com
4
Assistant Professor of Endocrinology and Metabolism, Faculty of Medicine, birjand University of Medical Sciences, Mashhad, Iran
LEAD_AUTHOR
1.Kannel WB, McGee DL. Diabetes and cardiovascular risk factors: the Framingham study. Circulation 1979; 59:8-13.
1
2.Desai NR, Giugliano RP, Zhou J, Kohli P, Somaratne R, Hoffman E, et al. AMG 145, a monoclonal antibody against
2
PCSK9, facilitates achievement of national cholesterol education program–adult treatment panel III low-density
3
lipoprotein cholesterol goals among high-risk patients: an analysis from the LAPLACE-TIMI 57 trial (LDL-C
4
assessment with PCSK9 monoclonal antibody inhibition combined with statin thErapy-thrombolysis in myocardial
5
infarction 57). J Am Coll Cardiol 2014; 63:430-3.
6
3.del Cañizo Gómez FJ, Fernández Pérez C, Moreno Ruiz I, de Gorospe Pérez-Jáuregui C, Silveira Rodríguez B,
7
González Losada T, et al. Microvascular complications and risk factors in patients with type 2 diabetes. Endocrinol
8
Nutr 2011; 58:163-8.
9
4.Stamler J, Vaccaro O, Neaton JD, Wentworth D. Diabetes, other risk factors, and 12-yr cardiovascular mortality for
10
men screened in the multiple risk factor intervention trial. Diabetes Care 1993; 16:434-44.
11
5.Dahlen GH, Guyton JR, Attar M, Farmer JA, Kautz JA, Gotto AM Jr. Association of levels of lipoprotein Lp (a),
12
plasma lipids, and other lipoproteins with coronary artery disease documented by angiography. Circulation 1986;
13
74:758-65.
14
6.Pyörälä K. Diabetes and coronary artery disease: what a coincidence? J Cardiovasc Pharmacol 1990; 16:S8-14.
15
7.Csaszar A, Dieplinger H, Sandholzer C, Karadi I, Juhasz E, Drexel H, et al. Plasma lipoprotein (a) concentration and
16
phenotypes in diabetes mellitus. Diabetologia 1993; 36:47-51.
17
8.Haffner SM, Morales PA, Stern MP, Gruber MK. Lp(a) concentrations in NIDDM. Diabetes 1992; 41:1267-72.
18
9.Woo J, Lam CW, Kay R, Wong HY, Teoh R, Nicholls MG. Acute and long-term changes in serum lipids after acute
19
stroke. Stroke 1990; 21:1407-11.
20
10.Kostner KM, Kostner GM. Lipoprotein(a): still an enigma? Curr Opin Lipidol 2002; 13:391-6.
21
11.Shlipak MG, Simon JA, Vittinghoff E, Lin F, Barrett-Connor E, Knopp RH, et al. Estrogen and progestin,
22
lipoprotein(a), and the risk of recurrent coronary heart disease events after menopause. JAMA 2000; 283:1845-52.
23
12.Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive summary of
24
the third report of the national cholesterol education program (NCEP) expert panel on detection, evaluation, and
25
treatment of high blood cholesterol in adults (Adult Treatment Panel III). JAMA 2001; 285:2486-97.
26
13.Hermans MP, Ahn SA, Rousseau MF. The mixed benefit of low lipoprotein(a) in type 2 diabetes. Lipids Health Dis
27
2017; 16:171.
28
14.Nestel PJ, Barnes EH, Tonkin AM, Simes J, Fournier M, White HD, et al. Plasma lipoprotein(a) concentration
29
predicts future coronary and cardiovascular events in patients with stable coronary heart disease. Arteriosclerosis
30
Thromb Vasc Biol 2013; 33:2902-8.
31
15.Thapa SD, KC SR, Gautam S, Gyawali D. Dyslipidemia in type 2 diabetes mellitus. J Pathol Nepal 2017; 7:1149-54.
32
16.Parhofer KG, Demant T, Ritter MM, Geiss HC, Donner M, Schwandt P. Lipoprotein (a) metabolism estimated by
33
nonsteady-state kinetics. Lipids 1999; 34:325-35.
34
17.Suk Danik J, Rifai N, Buring JE, Ridker PM. Lipoprotein(a), measured with an assay independent of
35
apolipoprotein(a) isoform size, and risk of future cardiovascular events among initially healthy women. JAMA 2006;
36
296:1363-70.
37
ORIGINAL_ARTICLE
Isolation of tetD, tetC, tetB, tetA genes from Acinetobacter bummani samples isolated from hospital samples by multiplex PCR method
Introduction: Acinetobacter is a gram negative bacterium seen as cocci or cocobacilli. This opportunistic bacterium plays a very important role in hospital infections. Tetracycline is a broad-spectrum antibiotic that inhibits the growth of many gram-positive and negative bacteria. Today, antibiotic resistance is not responding to the frequency of pathogenic bacteria and the risk of antibiotic resistant strains. The aim of this study was to determine the prevalence of antibiotic resistance and the distribution of tetracycline (tetD, tetC, tetB, tetA) genes in Acinetobacter bummani and antibiotic resistance Disc diffusion. Subjects & Methods: Acinetobacter bummani were isolated from clinical specimens and then identified by using bacteriological and biochemical tests. An antibiotic test was performed using CLSI standard method. By the PCR method, was investigated the presence of tetracycline resistance genes. Results: The highest resistance to acinetobacter isolates was resistance to ciprofloxacin. Out of 60 isolates of acinetobacter, the prevalence of tetA, tetB, tetC and tetD genes was 91.6, 91.6, 15, and 0%, respectively. This study concludes that resistance genes are present whether or not resistance genes are susceptible to many antibiotic groups. Conclusion: The main mechanisms for resistance to tetracycline are through the acquisition of the tet gene with the activity of the phallus pumps, ribosomal protection and enzymatic inactivation. An antibiotic resistance can be prevented by identifying antibiotic resistance patterns and using appropriate antibiotics when there is a need for treatment and preventing the release of resistant strains in the community among human populations.
https://mjms.mums.ac.ir/article_10772_0a85dff1883879f0f96ef6ec2374af4e.pdf
2018-01-21
734
742
10.22038/mjms.2018.10772
Acinetobacter
Disc diffusion
Tetracycline resistance genes
multiple polymerase chain reaction
Elham
Esmaeilzadeh Ashini
elham.esmailzadeh84@gmail.com
1
Department of Microbiology, Sirjan Branch, Islamic Azad University, Sirjan, Iran.
AUTHOR
Kumarss
Amini
dr_kumarss_amini@yahoo.com
2
Assistant Professor, Department of Microbiology, School of Basic Sciences, Saveh Branch, Islamic Azad University, Saveh, Iran
LEAD_AUTHOR
1. Murray PR, Rosenthal KS, Pfaller MA. Medical microbiology. New York: Elsevier Health Sciences; 2015. P. 632-84.
1
2. Nasonova E. Pulsed field gel electrophoresis: theory, instruments and applications. Tsitologiia 2008; 50:927-35.
2
3. Turlej A, Hryniewicz W, Empel J. Staphylococcal cassette chromosome mec (Sccmec) classification and typing methods: an overview. Pol J Microbiol 2011; 60:95-103.
3
4. Fagon JY, Chastre J, Domart Y, Trouillet JL, Gibert C. Mortality due to ventilator-associated pneumonia or colonization with Pseudomonas or Acinetobacter species: assessment by quantitative culture of samples obtained by a protected specimen brush. Clin Infect Dis 1996; 23:538-42.
4
5. Lim K, Hanifah YA, Yusof M, Thong KL. ermA, ermC, tetM and tetK are essential for erythromycin and tetracycline resistance among methicillin-resistant Staphylococcus aureus strains isolated from a tertiary hospital in Malaysia. Ind J Med Microbiol 2012; 30:203-7.
5
6. Gilan NR, Reshadat S, Ghasemi SR. The relationship between playing computer games and aggression in guidance school students of Kermanshah (2012). J Kermanshah Univ Med Sci 2013; 17:164-71.
6
7. Tavakol M, Momtaz H. Detection of the most prevalent antibiotic resistance genes in Acinetobacter baumannii strains isolated from hospital infections and determination of their antibiotic resistance pattern. Biol J Microorg 2015; 4:71-82 (Persian).
7
8. Momtaz H, Khamesipour F, Tavakol M, Awosile B. Determination of antimicrobial resistance and resistant genes in acinetobacter baumannii from human clinical samples. West Indian Med J 2015; 66:1.
8
9. Tille P. Bailey & Scott's diagnostic microbiology-e-book. New York: Elsevier Health Sciences; 2013. P. 276-355.
9
10. Hombach M, Bloemberg GV, Böttger EC. Effects of clinical breakpoint changes in CLSI guidelines 2010/2011 and EUCAST guidelines 2011 on antibiotic susceptibility test reporting of Gram-negative bacilli. J Antimicrob Chemother 2011; 67:622-32.
10
11. Jorgensen JH, Turnidge JD. Susceptibility test methods: dilution and disk diffusion methods. Manual of clinical microbiology. 11th ed. New York: American Society of Microbiology; 2015. P. 1253-73.
11
12. Su HC, Ying GG, Tao R, Zhang RQ, Fogarty LR, Kolpin DW. Occurrence of antibiotic resistance and characterization of resistance genes and integrons in Enterobacteriaceae isolated from integrated fish farms in south China. J Environ Monit 2011; 13:3229-36.
12
13. Berlau J, Aucken H, Houang E, Pitt TL. Isolation of Acinetobacter spp including A. baumannii from vegetables: implications for hospital-acquired infections. J Hosp Infect 1999; 42:201-4.
13
14. Durante-Mangoni E, Zarrilli R. Global spread of drug-resistant Acinetobacter baumannii: molecular epidemiology and management of antimicrobial resistance. Future Microbiol 2011; 6:407-22.
14
15. Choi CH, Lee EY, Lee YC, Park TI, Kim HJ, Hyun SH, et al. Outer membrane protein 38 of Acinetobacter baumannii localizes to the mitochondria and induces apoptosis of epithelial cells. Cell Microbiol 2005; 7:1127-38.
15
16. Dormanesh B, Mirnejad R, Khodaverdi Dariyan E, Momtaz H, Yahaghi E, Safarpour Dehkordi F, et al. Characterization and study the antibiotic resistance of Uropathogenic Escherichia coli isolated from pediatrics with pyelonephritis and cystitis in Iran. Iran J Med Microbiol 2013; 7:27-39 (Persian).
16
17. Potron A, Poirel L, Nordmann P. Emerging broad-spectrum resistance in Pseudomonas aeruginosa and Acinetobacter baumannii: mechanisms and epidemiology. Int J Antimicrob Agents 2015; 45:568-85.
17
ORIGINAL_ARTICLE
Evaluation of post-conditioning effects of morphine sulfate on Corrected TIMI frame count in patients with anterior ST-segment myocardial infarction who have undergone primary PCI on the left anterior descending artery
Introduction: Corrected TIMI Frame Count (CTFC) is a predictor of cardiovascular events in patients with ST-segment elevation myocardial infarction (STEMI). This study evaluated the post-conditioning effects of morphine on CTFC in the patients undergoing primary precutanous coronary intervention (PPCI) on left anterior descending artery (LAD). Subjects & Methods: This cross-sectional study was conducted on 40 patients with STEMI undergoing PPCI on LAD. Based on receiving or not receiving of 5-milligram morphine 30 minutes before PCI, patients allocated to two groups (sequentially 14 and 26 patients). Results: There was no significant difference between two groups considering of age, sex, coronary risk factor and pre-PCI CTFC. However, post-PCI CTFC, was lower in the morphine group (13.23±4.84 versus 13.10±6.80 in control group; P= 0.000). In both groups, a significant reduction observed in CTFC after PCI, which was more in morphine group (morphine versus control: 24.95±19.04 versus 24.32±19.05; P = 0.787) but not statistically significant. Conclusion: According to the findings of this study, it seems that in elective surgery, the replacement of crystalloids ringer and ringer's lactate, there is a significant difference in PH and postoperative complications following the use of these serums. The blood acidity following fluid therapy with ringer was higher in comparison to fluid therapy with ringer's lactate, and the delay in awakening in this group was reported high.
https://mjms.mums.ac.ir/article_10773_4bec022327f1d29e16cbf880ae1aed4e.pdf
2018-01-21
743
755
10.22038/mjms.2018.10773
It seems that usage of morphine before PPCI may lead to more reduction of post-procedural CTFC
but it is not statistically significant. surgery
Ramin
Khameneh Bagheri
khamenehbr@gmail.com
1
Assisstant professor of interventional cadrdiology, Division of Cardiovascular, Vascular Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Ali
Eshraghi
eshraghia@gmail.com
2
Associate professor of interventional cadrdiology, Division of Cardiovascular, Vascular Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
AUTHOR
Mostafa
Ahmadi
rkb.ma.95@gmail.com
3
Assistant Professor of interventional cardiology, Division of Cardiovascular and Vascular Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
LEAD_AUTHOR
1.Lloyd-Jones D, Adams R, Carnethon M, De Simone G, Ferguson TB, Flegal K, et al. Heart disease and stroke statistics--2009 update a report from the American heart association statistics committee and stroke statistics subcommittee. Circulation 2009; 119:e21-181.
1
2.Schuijf JD, Kaandorp TA, Lamb HJ, van der Geest RJ, Viergever EP, van der Wall EE, et al. Quantification of myocardial infarct size and transmurality by contrast-enhanced magnetic resonance imaging in men. Am J Cardiol 2004; 94:284-8.
2
3.Gibbons RJ, Valeti US, Araoz PA, Jaffe AS. The quantification of infarct size. J Am Coll Cardiol 2004; 44:1533-42.
3
4.Stenestrand U, Wallentin L; Swedish Register of Cardiac Intensive Care (RIKS-HIA). Early statin treatment following acute myocardial infarction and 1-year survival. JAMA 2001; 285:430-6.
4
5.Jong P, Yusuf S, Rousseau MF, Ahn SA, Bangdiwala SI. Effect of enalapril on 12-year survival and life expectancy in patients with left ventricular systolic dysfunction: a follow-up study. Lancet 2003; 361:1843-8.
5
6.Testa L, Van Gaal W, Zoccai GB, Agostoni P, Latini R, Bedogni F, et al. Myocardial infarction after percutaneous coronary intervention: a meta-analysis of troponin elevation applying the new universal definition. QJM 2009; 102:369-78.
6
7.Ridker PM, Rifai N, Pfeffer M, Sacks F, Lepage S, Braunwald E, et al. Elevation of tumor necrosis factor-α and increased risk of recurrent coronary events after myocardial infarction. Circulation 2000; 101:2149-53.
7
8.Marmor A, Sobel BE, Roberts R. Factors presaging early recurrent myocardial infarction (“extension”). Am J Cardiol 1981; 48:603-10.
8
9.Yellon DM, Hausenloy DJ. Myocardial reperfusion injury. N Engl J Med 2007; 357:1121-35.
9
10.Park JL, Lucchesi BR. Mechanisms of myocardial reperfusion injury. Ann Thoracic Surg 1999; 68:1905-12.
10
11.Zhao ZQ, Corvera JS, Halkos ME, Kerendi F, Wang NP, Guyton RA, et al. Inhibition of myocardial injury by ischemic postconditioning during reperfusion: comparison with ischemic preconditioning. Am J Physiol Heart Circ Physiol 2003; 285:H579-88.
11
12.Ferdinandy P, Schulz R, Baxter GF. Interaction of cardiovascular risk factors with myocardial ischemia/reperfusion injury, preconditioning, and postconditioning. Pharmacol Rev 2007; 59:418-58.
12
13.Kin H, Zhao ZQ, Sun HY, Wang NP, Corvera JS, Halkos ME, et al. Postconditioning attenuates myocardial ischemia–reperfusion injury by inhibiting events in the early minutes of reperfusion. Cardiovasc Res 2004; 62:74-85.
13
14.Hausenloy DJ, Tsang A, Yellon DM. The reperfusion injury salvage kinase pathway: a common target for both ischemic preconditioning and postconditioning. Trends Cardiovasc Med 2005; 15:69-75.
14
15.Cohen MV, Yang XM, Downey JM. Acidosis, oxygen, and interference with mitochondrial permeability transition pore formation in the early minutes of reperfusion are critical to postconditioning’s success. Basic Res Cardiol 2008; 103:464-71.
15
16.Huhn R, Heinen A, Weber NC, Schlack W, Preckel B, Hollmann MW. Ischaemic and morphine-induced post-conditioning: impact of mKCa channels. Br J Anaesth 2010; 105:589-95.
16
17.Schultz JE, Hsu AK, Gross GJ. Morphine mimics the cardioprotective effect of ischemic preconditioning via a glibenclamide-sensitive mechanism in the rat heart. Circulation Res 1996; 78:1100-4.
17
18.Burke AP, Virmani R. Pathophysiology of acute myocardial infarction. Med Clin North Am 2007; 91:553-72.
18
19.Christman KL, Lee RJ. Biomaterials for the treatment of myocardial infarction. J Am Coll Cardiol 2006; 48:907-13.
19
20.Karlsson L. Pharmacological interventions against myocardial ischemia and reperfusion injury. Sweden: Department of Molecular and Clinical Medicine; 2011.
20
21.Seino Y. Remote ischemic conditioning. Circ J 2013; 77:2883-5.
21
22.Heusch G, Bøtker HE, Przyklenk K, Redington A, Yellon D. Remote ischemic conditioning. J Am Coll Cardiol 2015; 65:177-95.
22
23.Saxena P, Newman MA, Shehatha JS, Redington AN, Konstantinov IE. Remote ischemic conditioning: evolution of the concept, mechanisms, and clinical application. J Card Surg 2010; 25:127-34.
23
24.Pagliaro P, Penna C. Cardiac postconditioning. Antioxid Redox Signal 2011; 14:777-9.
24
25.Zimmerman BJ, Granger DN. Mechanisms of reperfusion injury. Am J Med Sci 1994; 307:284-92.
25
26.Alvarez P, Tapia L, Mardones LA, Pedemonte JC, Farías JG, Castillo RL. Cellular mechanisms against ischemia reperfusion injury induced by the use of anesthetic pharmacological agents. Chem Biol Interact 2014; 218:89-98.
26
27.Rentoukas I, Giannopoulos G, Kaoukis A, Kossyvakis C, Raisakis K, Driva M, et al. Cardioprotective role of remote ischemic periconditioning in primary percutaneous coronary intervention: enhancement by opioid action. JACC Cardiovasc Interv 2010; 3:49-55.
27
28.Safi M, Vakili H, Saadat H, Khameneh BR, Ahmadi M. The comparison of intracoronary versus intravenous eptifibatide administration during primary percutaneous coronary intervention of acute ST-segment elevation myocardial infarction. Life Sci J 2012; 9:215-22.
28
29.Gaziano TA, Gaziano JM. Global burden of cardiovascular disease. In: Bonow RO, Mann DL, Zipes DP, Libby P, editors. Braunwald's heart disease: a textbook of cardiovascular medicine. Philadelphia: Elsevier Health Sciences; 2012. P. 1-18.
29
30.Ling Ling J, Wong G, Yao L, Xia Z, Irwin MG. Remote pharmacological post‐conditioning by intrathecal morphine: cardiac protection from spinal opioid receptor activation. Acta Anaesthesiol Scand 2010; 54:1097-104.
30
31.Gao DP, Zhao GQ, Wang J, Gao M. Effects of morphine postconditioning on myocardial ischemia-reperfusion injury in rats in vivo. Adv Mater Res 2013; 680:617-9.
31
32.Zhang R, Shen L, Xie Y, Gen L, Li X, Ji Q. Effect of morphine-induced postconditioning in corrections of tetralogy of fallot. J Cardiothorac Surg 2013; 8:76.
32
ORIGINAL_ARTICLE
The effect of cardiac rehabilitation and coenzyme q10 supplementation on functional capacity and ejection fraction in patients with heart failure
Introduction: Heart failure is one of the causes of death in cardiovascular patients. The aim of this study was the survey the effects of cardiac rehabilitation and co q10 on functional capacity (FC) and ejection fraction (EF) in patients with heart failure. Subjects & Methods: In this experimental study 4o patients were recruited and assigned to four groups: cardiac rehabilitation, coq10, rehab+coq10 and control, randomly. (Each group 10 patients). Patients in rehab group have performed recommended exercise three times a week, (Each time between 25 to 45 minutes) with 60 to 80% intensity of maximal heart rate. According to the result of Borg test and patient's capacity in every time, the intensity of exercise was increased for the next time. The second group was consumed 100 MG two times per day. The third group tried to do the exercise and consumed co q10. Exercise test was used to determine FC and Echocardiography was done to determine the EF, before and 8 weeks after the intervention. Results: Paired T test showed that, the mean scores of FC and EF were increased significantly in three interventional groups (P<0/05). According to covariance test, METs and EF were increased significantly both in rehab and rehab plus coq10 comparing to co q10 group. Above mentioned items had significant difference in 3 interventional groups comparing to the control (P<0/05). Conclusion: Doing rehab and consuming of coq10 specially integration of these two methods result in increasing of METs and EF which finally effected on improving the signs of heart failure in patients
https://mjms.mums.ac.ir/article_10774_b7d2a80043a42441c40d88bb67da491a.pdf
2018-01-21
756
766
10.22038/mjms.2018.10774
Cardiac rehabilitation
Coq10
functional capacity
ejection fraction
heart failure
Samira
Esteki
estekisamira@yahoo.com
1
PhD student in Exercise physiology, Department of Physical Education and Sport Sciences, science and research Branch , Islamic Azad University, Tehran, Iran
AUTHOR
khosro
Ebrahim
k-ebrahim@sbu.ac.ir
2
Professor, Department of Physical Education and Sport Sciences, Faculty of Physical Education and Sport Sciences, Shaheed Beheshti University, Tehran, Iran.(Corresponding Author)
LEAD_AUTHOR
Mandana
Gholami
gholami_man@yahoo.com
3
Associate Professor, Department of Physical Education and Sport Sciences, science and research Branch, Islamic Azad University, Tehran, Iran
AUTHOR
Rozita
Jalalian
rozitajalalian@yahoo.com
4
Assistant Professor, Faculty of Medicine, University of Sari Medical Sciences, Mazandaran, Iran
AUTHOR
1. Gorski PA, Ceholski DK, Hajjar RJ. Perspective. Cell Metab 2015; 21:183-94.
1
2. Jessup M, Albert NM, Lanfear DE, Lindenfeld J, Massie BM, Walsh MN, et al. ACCF/AHA/HFSA 2011 survey results: current staffing profile of heart failure programs, including programs that perform heart transplant and mechanical circulatory support device implantation. J Cardiac Failure 2011; 17:349-58.
2
3. Esfahani MA, Jolfaii EG, Torknejad M, Etesampor A, Amiz FR. Postprandial hypertriglyceridemia in non-diabetic patients with coronary artery disease. Indian Heart J 2004; 56:307-9.
3
4. Mishra P, Samanta L. Oxidative stress and heart failure in altered thyroid States. Sci World J 2012; 2012:741861.
4
5. Schairer JR, Keteyian SJ, Ehrman JK, Brawner CA, Brakebile ND. Leisure time physical activity of patients in maintenance cardiac rehabilitation. J Cardiopulm Rehabil 2003; 23:260-5.
5
6. The top 10 causes of death. Report No: Fact Sheet No. 310. World Health Organization. Available at: URL: www.who.int/mediacentre/ factsheets/fs310/en/index.html; 2008.
6
7. Leon AS, Franklin BA, Costa F, Balady GJ, Berra KA, Stewart KJ, et al. Cardiac rehabilitation and secondary prevention of coronary heart disease. Circulation 2005; 111:369-76.
7
8. Freeman LM, Roubenoff R. The nutrition implications of cardiac cachexia. Nutr Rev 1994; 52:340-7.
8
9. Khatta M, Alexander BS, Krichten CM, Fisher ML, Freudenberger R, Robinson SW, et al. The effect of coenzyme Q10 in patients with congestive heart failure. Ann Intern Med 2000; 132:636-40.
9
10. Pepe S, Marasco SF, Haas SJ, Sheeran FL, Krum H, Rosenfeldt FL. Coenzyme Q10 in cardiovascular disease. Mitochondrion 2007; 7:S154-67.
10
11. Rosenfeldt F, Hilton D, Pepe S, Krum H. Systematic review of effect of coenzyme Q10 in physical exercise, hypertension and heart failure. Biofactors 2003; 18:91-100.
11
12. Okello E, Jiang X, Mohamed S, Zhao Q, Wang T. Combined statin/coenzyme Q10 as adjunctive treatment of chronic heart failure. Med Hypotheses 2009; 73:306-8.
12
13. Madmani ME, Solaiman AY, Agha KT. Coenzyme Q10 for heart failure. Cochrane Database Syst Rev 2014; 6:1-33.
13
14. Sander S, Coleman CI, Patel AA, Kluger J, White CM. The impact of coenzyme Q10 on systolic function in patients with chronic heart failure. J Card Fail 2006; 12:464-72.
14
15. Bonow RO, Mann DL, Zipes DP, Libby P. Braunwald's heart disease e-book: a textbook of cardiovascular medicine. New York: Elsevier Health Sciences; 2011.
15
16. Berra K, Hamm LF, Kavanagh T. AACVPR cardiac rehabilitation resource manual. Champaign: Human Kinetics; 2006. P. 215.
16
17. Kargarfard M, Basati F, Sadeghi M, Rouzbehani R, Golabchi A. Effects of a cardiac rehabilitation program on diastolic filling properties and functional capacity in patients with myocardial infarction. J Isfahan Med Sch 2011; 29:243-52. (Persian)
17
18. Shabani R, Nikbakht H, Niko M, Cheraghi M. The effect of cardiac rehabilitation on functional capacity, blood pressure, oxygen consumption myocardial after surgery coronary artery. J Med Sci Islam Azad Univ Hamedan 2011; 21:108-13. (Persian)
18
19. Ahmad T, Fiuzat M, Mark DB, Neely B, Neely M, Kraus WE, et al. The effects of exercise on cardiovascular biomarkers in patients with chronic heart failure. Am Heart J 2014; 167:193-202.
19
20. Chicco AJ, McCune SA, Emter CA, Sparagna GC, Rees ML, Bolden DA, et al. Low-intensity exercise training delays heart failure and improves survival in female hypertensive heart failure rats. Hypertension 2008; 51:1096-102.
20
21. O'Connor CM, Whellan DJ, Lee KL, Keteyian SJ, Cooper LS, Ellis SJ, et al. Efficacy and safety of exercise training in patients with chronic heart failure: HF-Action randomized controlled trial. JAMA 2009; 301:1439-50.
21
22. Zilaee Bori S, Nikbakht M, Ahmadi F, Shakeriyan S, Beiranvand G. The effect of continuous and periodic aerobic exercise on oxygen consumption and ejection fraction, after coronary artery bypass surgery. Res Sport Sci 2011; 28:115-28. (Persian)
22
23. Fotino AD, Thompson- Paul AM, Bazzano LA. Effect of Coenzyme Q10 supplement on heart failure: a meta-analysis. Am J Clin Nutr 2013; 97:268-75.
23
24. Mortensen SA, Rosenfeldt F, Kumar A, Doliner P, Filipiak KJ, Pella D, et al. The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial. JACC Heart Fail 2014; 2:641-9.
24
25. Pourmoghaddas M, Rabbani M, Shahabi J, Garakyaraghi M, Khanjani R, Hedayat P. Combination of atorvastatin/coenzyme Q10 as adjunctive treatment in congestive heart failure: a double-blind randomized placebo-controlled clinical trial. ARYA Atheroscler 2014; 10:1-5.
25
26. Belardinelli R, Mucay A, Lacalaprice F, Solenghi M, Seddaiu G, Principi F. Coenzyme Q10 and exercise training in chronic heart failure. Eur Heart J 2006; 27:2675-81.
26
27. Molyneux SL, Florkowski CM, George PM, Pilbrow AP, Frampton CM, Lever M, et al. Coenzyme Q10: an independent predictor of mortality in chronic heart failure. J Am Coll Cardiol 2008; 52:1435-41.
27
ORIGINAL_ARTICLE
Evaluation of serum level of homocysteine in patients with ischemic stroke
Introduction: Stroke is the third most common cause of death in the world. The risk of emerging factors for stroke is plasma homocysteine. Subjects & Methods: A descriptive-analytic study was performed on patients with ischemic stroke referring to Tabriz hospitals. We entered the patients' information, including demographic information of patients, hypertension and etc along with laboratory results of homocysteine assay for patients' blood samples into SPSS v16 statistical analysis program. Results: A total of100 patients with ischemic stroke were evaluated who their average age was 65.83±15.32 years and also 54.54% were men and 46% were women, 45% were with one risk factor, 50% had hypertension, 13% diabetes, 18% hyperlipidemia, 14% a recent MI history and 31% had smoking history. Overall 74% of patients were with no stroke history, homosystein level in studied patients was 20.40±12.24 mmol/lit and 49% had normal level of homosystein. Homosystein level was evaluated with gender (p=0.876), age (p=0.004) and NIHSS (p=0.745) and also NIHSS level with gender (p=0.058), age (p=0.876), HTN (p=0.070), HLP (p=0.103), DM (p=0.999), and history of MI (p=0.262) and history of CVA (p=0.964), NIHSS level with smoking (p=0.109) and homosystein level (p=0.013). Data analysis showed that the level of homocysteine with hypertension (P=0.021) has a significant relationship. Conclusion: The results of this study showed that increased homocysteine has a high prevalence in patients with stroke.
https://mjms.mums.ac.ir/article_10783_70e469eed69ab5f585117e6960dc9f78.pdf
2018-01-21
767
778
10.22038/mjms.2018.10783
Serum level
Homocysteine
Ischemic stroke
Ssjjad
Jamali
sjamali95@yahoo.com
1
Laboratory Sciences Department, Islamic Azad University of Tabriz, Tabriz, Iran.
LEAD_AUTHOR
Behzad
Jamali
behzad.jamali@yahoo.com
2
Laboratory Sciences Department, Islamic Azad University of Ardabil, Ardabil, Iran.
AUTHOR
Hashem
Yagoubi
dr.hashemyagoubi@yahoo.com
3
Department of biology, Ardabil Branch, ialamic Azad university, Ardabil, iran
AUTHOR
1.Whlter G, Bradly, Robert B, Daroff, Gelad M, Fenichel, Janicovic J. Neurology in clinical practice, Byutterworth
1
Heinemann. 5 th ed. 2007. p. 1165-70, p. 764-68.
2
2. James F, Toole M, malinow R, Lioyd E, Chambless, et al. Lowering homocysteine in patients with ischemic stroke.
3
JAMA 2004;291 (51):565-75.
4
3. Giles WH, Kittner SJ, Anda KF, et al. serum folate and risk for ischemic stroke. stroke. 1995;26:1166-70.
5
4. Roses priepheral Brain. CVA Risk factors. JAMA 2001;285:2481.
6
5. Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL. Bradley’s neurology in clinical practice. 6th ed. New York:
7
Elsevier Health Sciences; 2012.
8
6. Sohrvardi SM, Azmandian J, Daryaee F, Mohammadpoor AH, Mehrabani M. Plasma Homocysteine Concentration
9
in Homodialysis patients of Kerman/Iran in 2005. Journal of kerman University of Medical Sciences 2007; 14:117-23.
10
[In Presian]
11
7. Ventura E, Durant R, Jaussent A, Picot MC, Morena M, Badiou S, et al. Homocysteine and inflammation as main
12
determinants of oxidative stress in the eldery. Free Radic Biol Med 2009; 46:737-44.
13
8. Kuwahara K, Nanri A, Pham NM. Kurotani K, Kume A, Sato M, et al. Serum vitamin B6, folate, and homocysteine
14
concentrations and oxidative DNA damage in Japanese men and women. Nutrition 2013;29:1219-23.
15
9. Artery Disease. Medical Journal of Tabriz University of Medical Sciences 2005;27:117- 23. [In Persian]
16
10. Bautista LE, Arenas IA, Penuela A, Martinez LX. Total plasma homocysteine level and risk of cardiovascular
17
disease: a meta-analysis of prospective cohort studies. J Clin Epidemiol 2002;55:882-7.
18
11. Casas JP, Bautista LE, Smeeth L, Sharma P, Hingorani AD. Homocysteine and stroke: evidence on a causal link
19
from mendelian randomisation. Lancet 2005;365:224-32.
20
12. Dominguez LJ, Galioto A, Pineo A, Ferlisi A, Ciaccio M, Putignano E, et al. Age, homocysteine, and oxidative
21
stress: relation to hypertension and type 2 diabetes mellitus. J Am Coll Nutr 2010;29:1-6.
22
13. McCully KS. Vascular pathology of homocsteinemia: implications for the pathogenesis of arteriosclerosis. Am J
23
Pathol 1969; 56:111-28.
24
14. Saposnik G, Ray JG, Sheridan P, McQueen M, Lonn E. Homocysteine-lowering therapy and stroke risk, severity,
25
and disability: additional finding from the HOPE 2 trial. Stroke. Stroke 2009; 40:1365-72.
26
15. Masoud S, Koochaki E, Mousavi G. Studying the correlation between stroke and serum level of homocysteine, folic
27
acid and vitamin B12. Ann Mil Health Sci Res 2009; 7:169-73 (Persian).
28
16. 24. Monshi KA, Mohtadi NJ, Farhoodi M, Aref Hosseini SR. Relationship between smoking status, vitamin B12
29
and folic acid, with homocysteine in patients with ischemic Stroke. Med J Tabriz Univ Med Sci 2011; 33:81-6
30
(Persian).
31
17. Zongte Z, Shaini L, Debbarma A, Singh TB, Devi SB, Singh WG. Serum homocysteine levels in cerebrovascular
32
accidents. Indian J Clin Biochem 2008; 23:154-7.
33
18. . Osunkalu V, Onajole A, Odeyemi K, Ogunnowo B, Sekoni A, Ayoola G, et al. Homocysteine and folate levels as
34
indicators of cerebrovascular accident. J Blood Med 2010; 1:131-4.
35
19. Mazdeh M, Monsef AR, Kashani KM. Study of relationship between homocysteine and stroke. Sci J Hamdan Univ
36
Med Sci 2006; 12:11-6.
37
20. Li ZH, Sun L, Zhang H, Liao Y, Wang D, Zhao B, et al. Elevated plasma homocysteine was associated with
38
hemorrhagic and ischemic stroke, but methylenetetrahydrofolate reductase gene C677T Polymorphism was a risk factor
39
for thrombotic stroke: a multicenter case-control study in China. Stroke 2003; 34:2085-90.
40
21. Iso H, Moriyama Y , sato S, Kitamura A. Serum Total Homocysteine concentrations and Risk of Stroke and its
41
Subtypes in Japanese. Circulation 2004;109:2766-2772.
42
22. Meiklejohn DJ, Vickers MA, Dijkhuisen R, Greaves M. Plasma homocysteine concentrations in the acute and
43
convalescent periods of atherothrombotic stroke. Stroke 2001; 32:57-62.
44
23. Masoud S, Koochaki E, Mousavi G. Studying the correlation between stroke and serum level of homocysteine, folic
45
acid and vitamin B12. Ann Mil Health Sci Res 2009; 7:169-73 (Persian).
46
24. Li ZH, Sun L, Zhang H, Liao Y, Wang D, Zhao B, et al. Elevated plasma homocysteine was associated with
47
hemorrhagic and ischemic stroke, but methylenetetrahydrofolate reductase gene C677T Polymorphism was a risk factor
48
for thrombotic stroke: a multicenter case-control study in China. Stroke 2003; 34:2085-90.
49
25. Meiklejohn DJ, Vickers MA, Dijkhuisen R, Greaves M. Plasma homocysteine concentrations in the acute and
50
convalescent periods of atherothrombotic stroke. Stroke 2001; 32:57-62.
51
26. Masoud S, Koochaki E, Mousavi G. Studying the correlation between stroke and serum level of homocysteine, folic
52
acid and vitamin B12. Ann Mil Health Sci Res 2009; 7:169-73 (Persian).
53
27. Zongte Z, Shaini L, Debbarma A, Singh TB, Devi SB, Singh WG. Serum homocysteine levels in cerebrovascular
54
accidents. Indian J Clin Biochem 2008; 23:154-7.
55
28. . Moini L, Mousavi AJ. Study of frequency distribution of homocysteinemia in patients admitted to ICU of Rasoul-
56
Akram hospital 2005. J Arak Univ Med Sci 2008; 4:50-6 (Persian).
57
29. Zhang W, Sun K, Chen J, Liao Y, Qin Q, Ma A, et al. High plasma homocysteine levels contribute to the risk of
58
stroke recurrence and all-cause mortality in a large prospective stroke population. Clin Sci 2009; 118:187-94.
59
ORIGINAL_ARTICLE
Effect of 6 Weeks of Low-volume High-intensity Interval Training on Antioxidant Defense and Aerobic Power in Female Survivors of Breast Cancer
Introduction: Antioxidant defense and aerobic fitness of patients with breast cancer are not favorable in the disease, treatment and post-treatment phases. Considering the likely role of exercise training on the antioxidant status, the present study aimed to investigate the effect of 6 weeks of low-volume high-intensity interval training (LVHIIT) on antioxidant defense and aerobic power in female survivors of breast cancer. Subjects & Methods: In this clinical trial study, 20 breast cancer survivors (mean age 44.90±2.82 years old) randomly divided into experimental (n=10) and control (n=10) groups. The experimental group participated in a six weeks of LVHIIT (three session per week). Total antioxidant capacity and Malondialdehyde levels were measured by ELISA kits and aerobic power by Balke Protocol. Data were analyzed using paired and independent t-test. Results: Total antioxidant capacity significantly improved (P=0.007) and Malondialdehyde levels significantly decreased (P=0.009). Also, aerobic power significantly improved (P=0.001). Conclusion: Six weeks of low-volume high-intensity interval training can improve the body's antioxidant status and aerobic power in patients with breast cancer and as a result, play an important role in prevention of breast cancer recurrence.
https://mjms.mums.ac.ir/article_10742_8b2112b7db880fb1be47c491b2ef72eb.pdf
2018-01-21
779
791
10.22038/mjms.2018.10742
Breast Cancer
Oxidative stress
Lipid Peroxidation
High-intensity interval training
Samira
Emadi
emadisamera1@gmail.com
1
MSc in Exercise Physiology, Department of Exercise Physiology, Shahrekord University, Shahrekord, Iran.
AUTHOR
Akbar
Azamian Jazi
azamianakbar@yahoo.com
2
Associate Professor of Exercise Physiology / Department of Sport sciences, Shahrekord University, Shahrekord, Iran.
LEAD_AUTHOR
Simin
Hemati
hemattiii@med.mui.ac.ir
3
Assistant Professor, Departments of Radiotherapy and Oncology, Isfahan University of Medical Sciences, Isfahan, Iran
AUTHOR
1.Barrera G. Oxidative stress and lipid peroxidation products in cancer progression and therapy. ISRN Oncol 2012;
1
2012:137289.
2
2.Abdel-Salam OM, Youness ER, Hafez HF. The antioxidant status of the plasma in patients with breast cancer undergoing chemotherapy. Open J Mol Integrat Phys 2011; 1:29-35.
3
3.Kruk J. Overweight, obesity, oxidative stress and the risk of breast cancer. Asian Pac J Cancer Prev 2014; 15:9579-86.
4
4.Nourazarian AR, Kangari P, Salmaninejad A. Roles of oxidative stress in the development and progression of breast cancer. Asian Pac J Cancer Prev 2014; 15:4745-51.
5
5.Wang M, Dhingra K, Hittelman WN, Liehr JG, de Andrade M, Li D. Lipid peroxidation-induced putative malondialdehyde-DNA adducts in human breast tissues. Cancer Epidemiol Biomarkers Prev 1996; 5:705-10.
6
6.Huang YL, Sheu JY, Lin TH. Association between oxidative stress and changes of trace elements in patients with breast cancer. Clin Biochem 1999; 32:131-6.
7
7.Ray G, Batra S, Shukla NK, Deo S, Raina V, Ashok S, et al. Lipid peroxidation, free radical production and antioxidant status in breast cancer. Breast Cancer Res Treat 2000; 59:163-70.
8
8.Khanzode SS, Muddeshwar MG, Khanzode SD, Dakhale GN. Antioxidant enzymes and lipid peroxidation in different stages of breast cancer. Free Radic Res 2004; 38:81-5.
9
9.Didziapetriene J, Smailyte G, Bublevic J, Kazbariene B, Kasiulevicius V, Stukas R. Relationship of MDA plasma concentrations to long-term survival of breast cancer patients. Tumori 2014; 100:333-7.
10
10.Dorgan JF, Sowell A, Swanson CA, Potischman N, Miller R, Schussler N, et al. Relationships of serum carotenoids, retinol, alpha-tocopherol, and selenium with breast cancer risk: results from a prospective study in Columbia, Missouri (United States). Cancer Causes Control 1998; 9:89-97.
11
11.Ching S, Ingram D, Hahnel R, Beilby J, Rossi E. Serum levels of micronutrients, antioxidants and total antioxidant status predict risk of breast cancer in a case control study. J Nutr 2002; 132:303-6.
12
12.Kumaraguruparan R, Subapriya R, Kabalimoorthy J, Nagini S. Antioxidant profile in the circulation of patients with fibroadenoma and adenocarcinoma of the breast. Clin Biochem 2002; 35:275-9.
13
13.Sener DE, Gonenc A, Akinci M, Torun M. Lipid peroxidation and total antioxidant status in patients with breast cancer. Cell Biochem Funct 2007; 25:377-82.
14
14.Madan K, Bhardwaj P, Thareja S, Gupta SD, Saraya A. Oxidant stress and antioxidant status among patients with nonalcoholic fatty liver disease (NAFLD). J Clin Gastroenterol 2006; 40:930-5.
15
15.Qi Y, Min H, Mujeeb A, Zhang Y, Han X, Zhao X, et al. Injectable hexapeptide hydrogel for localized chemotherapy prevents breast cancer recurrence. ACS Appl Mater Interfaces 2018; 10:6972-81.
16
16.Shahar S, Salleh RM, Ghazali AR, Koon PB, Mohamud WN. Roles of adiposity, lifetime physical activity and serum adiponectin in occurrence of breast cancer among Malaysian women in Klang Valley. Asian Pac J Cancer Prev 2010; 11:61-6.
17
17.Repka CP, Hayward R. Oxidative stress and fitness changes in cancer patients after exercise training. Med Sci Sports Exerc 2016; 48:607-14.
18
18.Hayes SC, Spence RR, Galvao DA, Newton RU. Australian association for exercise and sport science position stand: optimising cancer outcomes through exercise. J Sci Med Sport 2009; 12:428-34.
19
19.Rock CL, Doyle C, Demark-Wahnefried W, Meyerhardt J, Courneya KS, Schwartz AL, et al. Nutrition and physical activity guidelines for cancer survivors. CA Cancer J Clin 2012; 62:243-74.
20
20.Schmitz KH, Courneya KS, Matthews C, Demark-Wahnefried W, Galvao DA, Pinto BM, et al. American College of Sports Medicine roundtable on exercise guidelines for cancer survivors. Med Sci Sports Exerc 2010; 42:1409-26.
21
21.van den Berg JP, Velthuis MJ, Gijsen BC, Lindeman E, van der Pol MA, Hillen HF. Guideline "Cancer rehabilitation". Ned Tijdschr Geneeskd 2011; 155:A4104.
22
22.Irwin ML, Smith AW, McTiernan A, Ballard-Barbash R, Cronin K, Gilliland FD, et al. Influence of pre- and postdiagnosis physical activity on mortality in breast cancer survivors: the health, eating, activity, and lifestyle study. J Clin Oncol 2008; 26:3958-64.
23
23.Bloomer RJ, Fisher-Wellman KH. Blood oxidative stress biomarkers: influence of sex, exercise training status, and dietary intake. Gend Med 2008; 5:218-28.
24
24.Knez WL, Coombes JS, Jenkins DG. Ultra-endurance exercise and oxidative damage: implications for cardiovascular health. Sports Med 2006; 36:429-41.
25
25.Radak Z, Taylor AW, Ohno H, Goto S. Adaptation to exercise-induced oxidative stress: from muscle to brain. Exerc Immunol Rev 2001; 7:90-107.
26
26.Galantino ML, Stout NL. Exercise interventions for upper limb dysfunction due to breast cancer treatment. Phys Ther 2013; 93:1291-7.
27
27.Gibala MJ, Little JP, Macdonald MJ, Hawley JA. Physiological adaptations to low-volume, high-intensity interval training in health and disease. J Physiol 2012; 590:1077-84.
28
28.Bogdanis GC, Stavrinou P, Fatouros IG, Philippou A, Chatzinikolaou A, Draganidis D, et al. Short-term high-intensity interval exercise training attenuates oxidative stress responses and improves antioxidant status in healthy humans. Food Chem Toxicol 2013; 61:171-7.
29
29.Dolan LB, Campbell K, Gelmon K, Neil-Sztramko S, Holmes D, McKenzie DC. Interval versus continuous aerobic exercise training in breast cancer survivors--a pilot RCT. Support Care Cancer 2016; 24:119-27.
30
30.Clarkson PM, Thompson HS. Antioxidants: what role do they play in physical activity and health? Am J Clin Nutr 2000; 72:637S-46S.
31
31.Mijwel S, Backman M, Bolam KA, Jervaeus A, Sundberg CJ, Margolin S, et al. Adding high-intensity interval training to conventional training modalities: optimizing health-related outcomes during chemotherapy for breast cancer: the OptiTrain randomized controlled trial. Breast Cancer Res Treat 2018; 168:79-93.
32
32.Toohey K, Pumpa K, McKune A, Cooke J, DuBose KD, Yip D, et al. Does low volume high-intensity interval training elicit superior benefits to continuous low to moderate-intensity training in cancer survivors? World J Clin Oncol 2018; 9:1-12.
33
33.Pescatello LS, Arena R, Riebe D, Thompson PD. ACSM’s Guidelines for Exercise Testing and Prescription. 9th ed. Philadelphia: Lippincott Williams & Wilkins; 2014. P. 69-70, 80.
34
34.Pollock ML, Foster C, Schmidt D, Hellman C, Linnerud AC, Ward A. Comparative analysis of physiologic responses to three different maximal graded exercise test protocols in healthy women. Am Heart J 1982; 103:363-73.
35
35.Toohey K, Pumpa KL, Arnolda L, Cooke J, Yip D, Craft PS, et al. A pilot study examining the effects of low-volume high-intensity interval training and continuous low to moderate intensity training on quality of life, functional capacity and cardiovascular risk factors in cancer survivors. Peer J 2016; 4:e2613.
36
36.Azamian Jazi A, Emdi S, Hemati S. Effect of six weeks of continuous running on oxidative stress, lipid peroxidation and aerobic power in female survivors of breast cancer. Iran J Obstet Gynecol Infertil 2017; 19:24-32 (Persian).
37
37.Karimi N, Roshan VD. Change in adiponectin and oxidative stress after modifiable lifestyle interventions in breast cancer cases. Asian Pac J Cancer Prev 2013; 14:2845-50.
38
38.Wu B, Fukuo K, Suzuki K, Yoshino G, Kazumi T. Relationships of systemic oxidative stress to body fat distribution, adipokines and inflammatory markers in healthy middle-aged women. Endocr J 2009; 56:773-82.
39
39.Fathi BZ, Dabidi RV, Ayaz A, Hoseinzadeh M. The relationship between pro-inflammatory markers and lipid peroxidation after water-based regular exercise and ginger supplementation in patients with breast cancer. Daneshvar Med 2013; 20:61-76 (Persian).
40
40.Fatouros IG, Jamurtas AZ, Villiotou V, Pouliopoulou S, Fotinakis P, Taxildaris K, et al. Oxidative stress responses in older men during endurance training and detraining. Med Sci Sports Exerc 2004; 36:2065-72.
41
41.Radak Z, Chung HY, Goto S. Systemic adaptation to oxidative challenge induced by regular exercise. Free Radic Biol Med 2008; 44:153-9.
42
42.Gonenc A, Ozkan Y, Torun M, Simsek B. Plasma malondialdehyde (MDA) levels in breast and lung cancer patients. J Clin Pharm Ther 2001; 26:141-4.
43
43.Tupurani MA, Padala C, Kumar RG, Puranam K, Kumari S, Rani SH. Oxidative stress/Nitrosative stress in breast cancer. Hyderabad 2013; 1:14-20.
44
44.Pandey KB, Rizvi SI. Biomarkers of oxidative stress in red blood cells. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2011; 155:131-6.
45
45.Park SY, Kwak YS. Impact of aerobic and anaerobic exercise training on oxidative stress and antioxidant defense in athletes. J Exerc Rehabil 2016; 12:113-7.
46
46.Cazzola R, Russo-Volpe S, Cervato G, Cestaro B. Biochemical assessments of oxidative stress, erythrocyte membrane fluidity and antioxidant status in professional soccer players and sedentary controls. Eur J Clin Invest 2003; 33:924-30.
47
47.Usefpor M, Ghasemnian AA, Rahmani A. The effect of a period of high intensive interval training on total antioxidant capacity and level of liver tissue malondialdehyde in male wistar rats. Sci J Kurdistan Univ Med Sci 2017; 22:103-10 (Persian).
48
48.Brdareski Z, Djurovic A, Susnjar S, Zivotic-Vanovic M, Ristic A, Konstantinovic L, et al. Effects of a short-term differently dosed aerobic exercise on maximum aerobic capacity in breast cancer survivors: a pilot study. Vojnosanitet Pregl 2012; 69:237-42.
49
49.De Luca V, Minganti C, Borrione P, Grazioli E, Cerulli C, Guerra E, et al. Effects of concurrent aerobic and strength training on breast cancer survivors: a pilot study. Public Health 2016; 136:126-32.
50
50.Azamian Jazi A, Ghasemi Mobarekeh B, Vismeh Z, Parsa Gohar N. Effect of 12 weeks of selected Pilates exercise training on serum adiponectin level and insulin resistance in female survivors of breast cancer and its role in prevention of recurrence. Sci J Kurdistan Univ Med Sci 2015; 20:61-73 (Persian).
51
ORIGINAL_ARTICLE
Comparative study of two methods of fluid therapy with Ringer’s Lactate and Ringer’s solution
Introduction: Hypertension is a major health problem due to complications and high mortality rate. It causes problems in the ability of patients for self-care and affect their quality of life. This study was aimed to assess the effect of self-care education on quality of life and health literacy in patients with essential hypertension. Subjects & Methods: This quasi-experimental study was conducted using a pretest-posttest control group design. From patients with hypertension presenting to Mashhad Health Center, 90 patients were selected according to the eligibility criteria and were assigned randomly to two groups, the treatment group (45 patients) and the control group (45 patients). The research tool was quality of life questionnaires and test of functional health literacy in adults. The self-care education was conducted in 4 sessions. The obtained data were analyzed by means of analysis of covariance. Results: Regarding both the general mental and physical health, the quality of life had been divided in to before intervention psychologically 48/72 and physical health 51/47 which was increased to 71/97 psychologically, and 77/37 physically after the intervention. This difference was statistically significant in the mental aspect and physical health. Average health literacy in people before interference was 97/46 which increased to 130/31 after the intervention. This difference was statistically significant. Conclusion: Self-care education can improve quality of life and health literacy among patients with hypertension. It is recommended that health care providers, implement these educational programs for improving the quality of life and health literacy of patients with essential hypertension.
https://mjms.mums.ac.ir/article_10784_94182ff1423329cd007ffc85e7af51c2.pdf
2018-01-21
792
803
10.22038/mjms.2018.10784
Hypertension
Health Literacy
Quality of life
Self-care education
Susan
Gangi
susan.ganji94@gmail.com
1
MD, Dept. of Family Medicine, School of Medicine, Social Determinants of Health research center, Mashhad University of Medical Sciences (MUMS), Mashhad, Iran.
AUTHOR
Nooshin
Peyman
soheyla.meysami@gmail.com
2
Dept. of health education & health promotion, School of Health, Social Determinants of Health research center, Mashhad University of Medical Sciences (MUMS), Mashhad, Iran
LEAD_AUTHOR
Soheyla
Meysami bonab
sm_soda_1363@yahoo.com
3
Mashhad University of Medical Sciences, Mashhad, Iran
AUTHOR
Habibollah
Esmaily
esmailyh@mums.ac.ir
4
Department of Epidemiology and Biostatistics, Social Determinants of Health Research center, Mashhad University of Medical Sciences, Mashhad,Iran
AUTHOR
1. Sheikh Sharafi H, Seyedamini B. Assessment of health literacy and self-care in heart failure patients. J Health Literacy 2016; 1:203-19. (Persian)
1
2. Jekel JF, Katz DL, Elmore JG, Wild D. Epidemiology, biostatistics and preventive medicine. 2nd ed. Philadelphia: Saunders Company; 2001. P. 221-3.
2
3. Wang Y, Wang QJ. The prevalence of pre hypertension and hypertension among us adults according to the new joint national committee guidelines, new challenges of the old problem. Arch Intern Med 2004; 164:2126-34.
3
4. Mansoorian M, Qorbani M, Shafieyan N, Asayesh H, Shafieyan Z, Maghsodloo D. Association between life style and hypertension in rural population of Gorgan. J Health Promo Manage 2012; 1:23-8. (Persian)
4
5. Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr, et al. National heart, lung, and blood institute joint national committee on prevention, detection, evaluation, and treatment of high blood pressure; national high blood pressure education program coordinating committee. The seventh report of the joint national committee on prevention, detection, high blood pressure. JAMA 2003; 289:2560-72.
5
6. Arslantas D, Ayranci U, Unsal A, Tozun M. Prevalence of hypertension among individuals aged 50 years and over and its impact on health related quality of life in a semi-rural area of western Turkey. Chin Med J 2008; 121:1524-31.
6
7. Beto JA, Bansal VK. Quality of life in treatment of hypertension. A metaanalysis of clinical trials. Am J Hypertens 1994; 7:286-7.
7
8. Deyo RA. The quality of life and research and care. Ann Int Med 1991; 114:695-7.
8
9. Alexander R, Pratt C, Ryan T. The heart. 11th ed. New York: Graw-Hill; 2004. P. 13-5.
9
10. Carvalho MV, Siqueira LB, Sousa AL, Jardim PC. The influence of hypertension on quality of life. Arq Bras Cardiol 2013; 100:164-74.
10
11. Ebadi A, Shamsi A, Refahi AA, Saied Y. Comparison of the quality of life in men with and without hypertension. Sci J Hamadan Nurs Midwifery Facul 2012; 20:5-15. (Persian)
11
12. Nama S, Chesla C, Stotts NA, Kroon L, Janson SL. Barriers to diabetes management: patient and provider factors. Diabetes Res Clin Pract 2011; 93:1-9.
12
13. Tol A, Pourreza A, Rahimi Foroshani A, Tavassoli E. Assessing the effect of educational program based on small group on promoting knowledge and health literacy among women with type 2 diabetes referring to selected hospitals affiliated to Tehran University of Medical Sciences. Razi J Med Sci 2013; 19:104. (Persian)
13
14. Reisi M, Javadzade SH, Mostafavi F, Sharifirad G, Radjati F, Hasanzade A. Relationship between health literacy, health status, and healthy behaviors among older adults in Isfahan, Iran. J Educ Health Promot 2012; 1:31. (Persian)
14
15. Aziznejad P, Kashaninia Z. Effect of self-care training on applying coping strategies of adolescents. Bim J Hormozgan Univ Med Sci 2006; 10:256-72. (Persian)
15
16. Khosravi A, Ahmadzade K. Investigating health literacy level of patients referred to Bushehr hospitals and recognizing its effective factors. Iran South Med J 2016; 18:1245-53. (Persian)
16
17. Aovisi S, Aimanzade N, Basir Z, Jovadi Z. Fundamental nursing. Potter and Perry. Tehran: Salami; 2003. P. 182-3.
17
18. Oreizy HR, Farahani HA. Applied research methods in clinical psychology. Tehran: Danzhh; 2009. (Persian)
18
19. Beigi MA, Zibaeenezhad MJ, Aghasadeghi K, Jokar A, Shekarforoush S, Khazraei H. The effect of educational programs on hypertension management. Int Cardivasc Res 2014; 8:94-8. (Persian)
19
20. Ware JE, Snow KK, Koshinski M, Gndek B. SF-36 Health survey: manual and interpretation guide. Boston: Health Institute; 1993.
20
21. Montazeri A, Goshtasebi A, Vahdaninia MS, Gandek B. The short form health survey (SF-36): translation and validation study of the Iranian version. Qual Life Res 2005; 14:875-82. (Persian)
21
22. Montazeri A, Goshtasebi A, Vahdaninia M, Gandek B. The short form health survey (SF-36): translation and validation study of the Iranian version. Qual Life Res 2005; 14:875-82. (Persian)
22
23. Lawrence WF, Fryback DG, Martin PA, Klein R, Klein BE. Health status and hypertension: a population-based study. J Clin Epidemiol 1996; 49:1239-45.
23
24. Hacihasanoglu R, Gozüm S. The effect of patient education and home monitoring on medication compliance, hypertension management, healthy lifestyle behaviours and BMI in a primary health care setting. J Clin Nurs 2011; 20:692-705.
24
25. Aghajani M, Ajorpaz NM, Atrian MK, Raofi Z, Abedi F, Vartoni SN, et al. Effect of self-care education on quality of life in patients with primary hypertension: comparing lecture and educational package. Nurs Midwifery Stud 2013; 2:71. (Persian)
25
26. Hunt JS, Siemienczuk J, Touchette D, Payne N. Impact of educational mailing on the blood pressure of primary care patients with mild hypertension. J Gen Intern Med 2004; 19:925-30.
26
27. Park YH, Song M, Cho BI, Lim JY, Song W, Kim S. The effects of an integrated health education and exercise program in community-dwelling older adults with hypertension: a randomized controlled trial. Patient Educ Couns 2011; 82:133-7.
27
28. Fernandez S, Scales KL, Pineiro JM, Schoenthaler AM, Ogedegbe G. A senior center-based pilot trial of the effect of lifestyle intervention on blood pressure in minority elderly people with hypertension. J Am Geriatr Soc 2008; 56:1860-6.
28
29. Baker DW, Gazmararian JA, Williams MV, Scott T, Parker RM, Green D, et al. Functional health literacy and the risk of hospital admission among Medicare managed care enrollees. Am J Public Health 2002; 92:1278-83.
29
30. Rosamond W, Flegal K, Furie K, Go A, Greenlund K, Haase N, et al. Heart disease and stroke statistics-2008 update. Circulation 2008; 117:e25-46.
30
31. Krokavcova M, van Dijk JP, Nagyova I, Rosenberger J, Gavelova M, Middel B, et al. Social support as a predictor of perceived health status in patients with multiple sclerosis. Patient Educ Couns 200; 73:159-65.
31
32. Amar J, Chamontin B, Genes N, Cantet C, Salvador M, Cambou JP. Why is hypertension so frequently uncontrolled in secondary prevention? J Hypertens 2003; 21:1199-205.
32
33. Reisi M, Mostafavi F, Javadzade H, Mahaki B, Tavassoli E, Sharifirad GH. Communicative and critical health literacy and self-care behaviors in patients with type 2 diabetes. Iran J Diabetes Metab 2015; 14:199-208. (Persian)
33
34. Ghanbari SH, Majlessi F, Ghaffari M, Mahmoudi Majdabadi M. Survey on health literacy of pregnant women in health centers of Shahid Beheshti University of medical sciences. Med J 2011; 19:1-13. (Persian)
34
35. Nekoei-Moghadam M, Parva S, Amiresmaili M, Baneshi M. Health literacy and utilization of health services in Kerman urban area 2011. Tolue Behdasht J 2012; 11:123-34. (Persian)
35
36. Lee SY, Tsai TI, Tsai YW, Kuo KN. Health literacy, health status, and healthcare utilization of Taiwanese adults: results from a national survey. BMC Public Health 2010; 10:614.
36
37. Jovic-Veranes A, Bejgovic-Mikanovic V, Marinkovic J, Kocev N. Health literacy in a population of primary healthcare patients in Belgrade, Serbia. Int J Public Health 2011; 56:201-7.
37
38. Schillinger D, Grumbach K, Piette J, Wang F, Osmond D, Daher C, et al. Association of health literacy with diabetes outcomes. JAMA 2002; 288:475-82.
38
39. Mosher HJ, Lund BC, Kripalani S, Kaboli PJ. Association of health literacy with medication knowledge, adherence, and adverse drug events among elderly veterans. J Health Commun 2012; 17:241-51.
39
40. Ngoh LN. Health literacy: a barrier to pharmacist-patient communication and medication adherence. J Am Pharm Assoc 2009; 49:e132-46.
40
41. Gehi AK, Mehta D, Gomes JA. Evaluation and management of patients after implantable cardioverter-defibrillator shock. JAMA 2006; 296:2839-47.
41
42. Mohammad HM, Farahani B, Zohour AR, Panahi AS. Self-care ability based on Orem’s theory in individuals with coronary artery disease. Iran J Crit Care Nurs 2010; 3:87-91. (Persian)
42
43. Long AF, Gambling T. Enhancing health literacy and behavioural change within a tele-care education and support intervention for people with type 2 diabetes. Health Expect 2012; 15:267-82.
43
44. Kandula NR, Nsiah-Kumi PA, Makoul G, Sager J, Zei CP, Glass S, et al. The relationship between health literacy and knowledge improvement after a multimedia type 2 diabetes education program. Patient Educ Couns 2009; 75:321-7.
44
45. Sharp LK, Lipsky MS The short-term impact of a continuing medical education program on providers’ attitudes toward treating diabetes. Diabetes Care 1999; 22:1929-32.
45
46. Khezerloo S, Feizi A. A survey of relationship between perceived self-efficacy and self-care performance in diabetic patients referring to Urmia diabetes center. J Urmia Nurs Midwifery Facul 2012; 10:1. (Persian)
46
ORIGINAL_ARTICLE
Effect of different resistance training modes on appetite and serum orexin, ghrelin, and neuropeptide Y levels in sedentary healthy males
Introduction: Different physical exercises play an important role in energy balance and weight control through affecting the appetite-regulating hormones. The aim of this study was to determine the effect of different resistance training modes on appetite and appetite-related hormones among sedentary healthy males. Subjects & Methods: This study was conducted on 40 healthy males with the mean age of 22.15±0.7 years and body mass index of 24.12±3.5 kg/m2. The study population was randomly assigned into four groups of control group (n=10), upper-body resistance training (n=10), lower-body resistance training, and full body resistance training. Trainings were performed three sessions a week for eight weeks. The fasting blood samples were obtained from the antecubital vein before and 48 h after the last session of the resistance training for the evaluation of plasma growth hormone, orexin, ghrelin, acyl ghrelin, and neuropeptide Y (NPY) using ELISA method. In addition, the desire to eat was measured by means of the appetite questionnaire. Results: According to the results, plasma growth hormone, orexin, ghrelin, and acyl ghrelin were increased significantly after lower-body and full body resistance trainings, compared to the pre-intervention stage. Meanwhile, the upper-body resistance training just resulted in the elevation of NPY (P=0.049). The enhancement of orexin level was more significant in the lower-body training group in comparison to that in the control group (P=0.001). Furthermore, the enhancement of ghrelin level was more significant in the full body (P=0.021) and lower-body (P=0.001) training groups than in the control group. On the other hand, the three intervention groups showed a higher elevation in NPY as compared to the control group. Additionally, desire to eat was increased after the three modes of training; however, there was no significant difference among the three training groups in this regard. Conclusion: As the findings indicated, resistance training, especially lower-body and full body resistance trainings, regulated appetite through the elevation of growth hormone, orexin, ghrelin, and NPY. Moreover, the type of resistance training affected the amount of appetite changes after adjusting to resistance training.
https://mjms.mums.ac.ir/article_10787_afcb50773deb00392b3bf9920def9166.pdf
2018-01-21
804
815
10.22038/mjms.2018.10787
GH
Orexin
Acyl ghrelin
NPY
Appetite
abdolreza
jafari chashmi
jafarychashmy@gmail.com
1
1- PhD in exercise physiology, Faculty of physical education and sport science, Islamic Azad University, Central Tehran Branch, Tehran, Iran.
AUTHOR
Maghsoud
Peeri
m.peeri@iauctb.ac.ir
2
2- Professor, Department of exercise physiology, Faculty of physical education and sport science, Islamic Azad University, Central Tehran Branch, Tehran, Iran.
LEAD_AUTHOR
Mohammad Ali
Azarbayjani
ali.azarbayjani@gmail.com
3
دانشگاه آزاد اسلامی واحد تهران مرکزی
AUTHOR
Hasan
Matin homaee
hasanmatinhomaee@gmail.com
4
Associate professor , Department of exercise physiology, Faculty of physical education and sport science, Central Tehran Branch, Islamic Azad University, Tehran, Iran.
AUTHOR
1. Bilski J, Teległów A, Zahradnik-Bilska J, Dembiński A, Warzecha Z. Effects of exercise on appetite and food intake regulation. Med Sport 2009; 13:82-94.
1
2. Shaabani M, Mohammadzade M, Azhdari-Zarmehri H. Orexin (hypocretin): a multi-functional hypothalamic peptide. Koomesh 2014; 15:275-81. (Persian)
2
3. World Health Organization. Obesity and overweight. Geneva: World Health Organization; 2013.
3
4. Al Awar R, Obeid O, Hwalla N, Azar S. Postprandial acylated ghrelin status following fat and protein manipulation of meals in healthy young women. Clin Sci 2005; 109(4):405-11.
4
5. King NA, Snell L, Smith RD, Blundell JE. Effects of short-term exercise on appetite responses in unrestrained females. Eur J Clin Nutr 1996; 50:663-7.
5
6. Laan DJ, Leidy HJ, Lim E, Campbell WW. Effects and reproducibility of aerobic and resistance exercise on appetite and energy intake in young, physically active adults. Appl Physiol Nutr Metab 2010; 35:842-7.
6
7. Balaguera-Cortes L, Wallman KE, Fairchild TJ, Guelfi KJ. Energy intake and appetite-related hormones following acute aerobic and resistance exercise. Appl Physiol Nutr Metab 36:958-66.
7
8. Bajer B, Vlcek M, Galusova A, Imrich R, Penesova A. Exercise associated hormonal signals as powerful determinants of an effective fat mass loss. Endocr Regul 2015; 49:151-63.
8
9. Strasser B, Siebert U, Schobersberger W. Resistance training in the treatment of the metabolic syndrome: a systematic review and meta-analysis of the effect of resistance training on metabolic clustering in patients with abnormal glucose metabolism. Sports Med 2010; 40:397-415.
9
10. Kraemer WJ, Ratamess NA. Hormonal responses and adaptations to resistance exercise and training. Sports Med 2005; 35:339-61.
10
11. Fleck SJ, Kraemer W. Designing resistance training programs. 4th ed. Canada: Human Kinetics; 2014.
11
12. Mokhtari M, Daryanoosh F. The effect of 12 weeks resistance exercise on plasma levels of Apelin-12, Nesfatin-1 and resting heart rate in hypertensive elderly women. Med J Mashhad Univ Med Sci 2015; 58(6):330-7. (Persian)
12
13. Stubbs RJ, Hughes DA, Johnstone AM, Rowley E, Reid C, Elia M, et al. The use of visual analogue scales to assess motivation to eat in human subjects: a review of their reliability and validity with an evaluation of new hand-held computerized systems for temporal tracking of appetite ratings. Br J Nutr 2000; 84:405-15.
13
14. Hopkins M, Blundell JE. Energy balance, body composition, sedentariness and appetite regulation: pathways to obesity. Clin Sci 2016; 130:1615-28.
14
15. Rocha J, Paxman J, Dalton C, Winter E, Broom DR. Effects of a 12-week aerobic exercise intervention on eating behaviour, food cravings, and 7-day energy intake and energy expenditure in inactive men. Appl Physiol Nutr Metab 2016; 41:1129-36.
15
16. Guelfi KJ, Donges CE, Duffield R. Beneficial effects of 12 weeks of aerobic compared with resistance exercise training on perceived appetite in previously sedentary overweight and obese men. Metabolism 2013; 62:235-43.
16
17. Neary NM, Goldstone AP, Bloom SR. Appetite regulation: from the gut to the hypothalamus. Clin Endocrinol 2004; 60:153-60.
17
18. Hazell TJ, Islam H, Townsend LK, Schmale MS, Copeland JL. Effects of exercise intensity on plasma concentrations of appetite-regulating hormones: potential mechanisms. Appetite 2016; 98:80-8.
18
19. Tiryaki-Sonmez G, Ozen S, Bugdayci G, Karli U, Ozen G, Cogalgil S, et al. Effect of exercise on appetite-regulating hormones in overweight women. Biol Sport 2013; 30:75-80.
19
20. Foster-Schubert KE, McTiernan A, Frayo RS, Schwartz RS, Rajan KB, Yasui Y, et al. Human plasma ghrelin levels increase during a one-year exercise program. J Clin Endocrinol Metab 2005; 90:820-5.
20
21. Martins C, Kulseng B, King NA, Holst JJ, Blundell JE. The effects of exercise-induced weight loss on appetite-related peptides and motivation to eat. J Clin Endocrinol Metab 2010; 95:1609-16.
21
22. Goto K, Shioda K, Uchida S. Effect of 2 days of intensive resistance training on appetite‐related hormone and anabolic hormone responses. Clin Physiol Funct Imaging 2013; 33:131-6.
22
23. Shimizu S, Nakamachi T, Konno N, Matsuda K. Orexin A enhances food intake in bullfrog larvae. Peptides 2014; 59:79-82.
23
24. Nakamachi T, Shibata H, Sakashita A, Iinuma N, Wada K, Konno N, et al. Orexin A enhances locomotor activity and induces anxiogenic-like action in the goldfish, Carassius auratus. Horm Behav 2014; 66:317-23.
24
25. Toshinai K, Date Y, Murakami N, Shimada M, Mondal MS, Shimbara T, et al. Ghrelin-induced food intake is mediated via the orexin pathway. Endocrinology 2003; 144:1506-12.
25
26. Friedman JM. The function of leptin in nutrition, weight, and physiology. Nutr Rev 2002; 60:S1-14.
26
27. Carnier J, de Mello MT, Ackel-D́Elia C, Corgosinho FC, da Silveira Campos RM, de Lima Sanches P, et al. Aerobic training (AT) is more effective than aerobic plus resistance training (AT+RT) to improve
27
anorexigenic/orexigenic factors in obese adolescents. Appetite 2013; 69:168-73.
28
ORIGINAL_ARTICLE
The Effectiveness of Positive Psychology Training and Cognitive Self-Compassion on Students' Self-efficacy, Burnout, and Academic Self-Regulation
Introduction: The purpose of this study was to compare the effectiveness of Positive Psychology training and cognitive self-efficacy, burnout and academic self-regulation in students. Materials & Methods: The method of this study was quasi-experimental with two experimental design nodes and control group. The statistical population consisted of the students of Islamic Azad University of Arak in the academic year 97-98. 45 students were selected using available sampling method and were randomly assigned into three experimental and control groups (15 students in each group). Participants completed the Miguel et al.'s (2000), Burns et al.'s (1997) academic self-efficacy questionnaires, and Bufard's (1995) academic self-regulation questionnaires. The hypotheses were tested by multivariate analysis of covariance and one-way analysis of variance. Results: The results showed that in the educational self-efficacy variable, positive psychology training and then cognitive self-compassion were respectively effective. In academic burnout variable, cognitive self-compassion training and positive psychology were respectively effective. Positive psychology and then cognitive self-compassion were respectively effective on academic self-regulation. Conclusion: Positive psychology training and cognitive self-compassion promote academic self-efficacy and self-regulation as well as decrease academic burnout.
https://mjms.mums.ac.ir/article_14260_108649aef44499a81f4c82b2e7bd18f8.pdf
2018-01-21
1649
1660
10.22038/mjms.2019.14260
Academic self-regulation
Cognitive self-compassion
Academic self-efficacy
Positive psychology
Academic burnout
Mohammad
Abbasi
1
PhD student, Department of Educational Psychology, Faculty of Humanities, Khomein Branch, Islamic Azad University, Khomein, Iran
AUTHOR
Hosseine
Davoodi
2
Assistant Professor, Faculty of Humanities, Khomein Branch, Islamic Azad University, Khomeini, Iran
LEAD_AUTHOR
Hasan
Heydari
3
Associate Professor, Faculty of Humanities, Khomein Branch, Islamic Azad University, Khomeini, Iran.
AUTHOR
Zabih
Pirani
4
Assistant Professor, Dept. of Educational Psychology, Faculty of Humanities, Arak Branch, Islamic Azad University, Arak, Iran.
AUTHOR
ORIGINAL_ARTICLE
Antibiotic Resistance Pattern of Pseudomonas aeruginosa Strains Isolated from Burn Patients
Background and Aim: Pseudomonas aeruginosa plays an important role in severe infections in burn patients. The sepsis caused by this bacterium is a serious complication of burn infection. The aim of this study was to determine the frequency and antibiotic resistance pattern of Pseudomonas aeruginosa isolated from wounded patients admitted to burn ward in Zahedan.Methods: In this descriptive cross-sectional study, 70 isolates of P. aeruginosa were collected from burn wound samples from Zahedan. After biochemical tests and confirmation of the bacterial strain, antibiotic resistance was determined for nine antibiotics by disk diffusion method according to Clinical Laboratory Standards Institute (CLSI) standard. The minimum inhibitory concentration (MIC) of imipenem, piperacillin tazobactam and ceftazidime was determined by E-test strips. Results: In this study, out of 70 P. aeruginosa isolates, the highest resistance to Trimethoprim /Sulfamethoxazole (84.3%) and cefepime (70.8%) was observed. The lowest resistance to piperacillin/tazobactam (20.8%) and colistin (8.3%) was report. E-test results showed the highest sensitivity to piperacillin/tazobactam.Conclusion: In this study, P. aeruginosa strains showed the least resistance to colistin and piperacillin/tazobactam. These antibiotics could be the main alternative for the treatment of pseudomonas infections caused by burns.
https://mjms.mums.ac.ir/article_14778_d41d8cd98f00b204e9800998ecf8427e.pdf
2018-01-21
1121
1131
10.22038/mjms.2019.14778
Antibiotic resistance
Nosocomial infection
Pseudomonas aeruginosa
Mojdeh
Jahantigh
mojde_jahan@yahoo.com
1
Department of Microbiology, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.
LEAD_AUTHOR
Hamed
Tahmasbi
h.tahmasebi87@yahoo.com
2
Department of Microbiology, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.
AUTHOR
Mohammad
Bakaeiyan
bokaeian.m@gmail.com
3
Department of Microbiology, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.
AUTHOR
Brooks LE, Ul-Hasan S, Chan BK, Sistrom MJ. Quantifying the evolutionary conservation of genes encoding multidrug efflux pumps in the ESKAPE pathogens to identify antimicrobial drug targets. Msystems 2018; 3:e00024-18.
1
Habibi A, Mozafari A, Fallah Mehrabadi J, Kazemi Darsanky R. The frequency and antibiotic resistance modeling in clinical strains of Pseudomonas aeruginosa isolated from different parts of Tehran hospitals. Razi J Med Sci 2016; 23:10-6.
2
Salehi M, Hekmatdoost M, Hosseini F. Quinolone resistance associated with efllux pumps mexAB-oprM in clinical isolates of Pseudomonas aeruginosa. J Microb World 2014; 6:290-98.
3
Mirsalehian A, Jabal AF, Mirafshar SM, Bazarjani F, Gorjipour A, Goli HR. Determination of antimicrobial resistance patterns and extended spectrum β lactamases in clinical isolates of coli. Tehran Univ Med J 2008; 66:373-8.
4
Radan M, Moniri R, Khorshidi A, Gilasi H, Norouzi Z, Beigi F, et al. Emerging carbapenem-resistant Pseudomonas aeruginosa isolates carrying blaIMP among burn patients in Isfahan, Iran. Arch Trauma Res 2016; 5:1-5.
5
Vaez H, Faghri J, Isfahani BN, Moghim S, Yadegari S, Fazeli H, et al. Efflux pump regulatory genes mutations in multidrug resistance Pseudomonas aeruginosa isolated from wound infections in Isfahan hospitals. Adv Biomed Res 2014; 3:1-5.
6
Aslani MM, Hahsemipour M, Nikbin VS, Shahcheraghi F, Eidi A, Sharafi Z. PCR identification of Pseudomonas aeruginosa based on two outermembrane lipoprotein oprI, oprL, and exotoxin A gene. Yafte 2009; 11:21-6.
7
Chatterjee M, Anju CP, Biswas L, Kumar VA, Mohan CG, Biswas R. Antibiotic resistance in Pseudomonas aeruginosa and alternative therapeutic options. Int J Med Microbiol 2016; 306:48-58.
8
Japoni A, Farshad S, Alborzi A. Pseudomonas aeruginosa: burn infection, treatment and antibacterial resistance. Iran Red Crescent Med J 2009; 11:244.
9
Behrouz B, Amirmozafari N, Fizabadi MM, Khoramabadi N, Bahroudi M, Mahdavi M. Passive immunity with recombinant anti-pseudomonas aeruginosa type B fagellin antibody in a burned mouse model. Arak Med Univ J 2015; 18:21-32.
10
McManus A, Mason AD, McManus WF, Pruitt BA. Twenty-five year review of Pseudomonas aeruginosa bacteremia in a burn center. Eur J Clin Microbiol 1985; 4:219-23.
11
Dashtizadeh Y, Garzin A. The prevalence of genetic and phenotypic assessment of efflux pumps and antibiotic resistance in Pseudomonas aeruginosa clinical samples in a hospital burn patients Qutb al-Din Shirazi. J Microbial World 2014; 2:118-27.
12
Pirnay JP, De Vos D, Cochez C, Bilocq F, Pirson J, Struelens M, et al. Molecular epidemiology of Pseudomonas aeruginosa colonization in a burn unit: persistence of a multidrug-resistant clone and a silver sulfadiazine-resistant clone. J Clin Microbiol 2003; 41:1192-202.
13
Magiorakos AP, Srinivasan A, Carey RB, Carmeli Y, Falagas ME, Giske CG, et al. Multidrug‐resistant, extensively drug‐resistant and pandrug‐resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance. Clin Microbiol Infect 2012; 18:268-81.
14
Nahaei MR, Nahaei M, Sadeghi J, Beygoli N. Genotyping and antibiotic susceptibility patterns of Pseudomonas aeruginosa isolated from burn ward of Sina hospital in Tabriz. Med J Tabriz Uni Med Sci Health Serv 2017; 38:74-83.
15
Munder A, Wölbeling F, Kerber-Momot T, Wedekind D, Baumann U, Gulbins E, et al. Acute intratracheal Pseudomonas aeruginosa infection in cystic fibrosis mice is age-independent. Respir Res 2011; 12:148.
16
Khosravi AD, Mihani F. Detection of metallo-β-lactamase–producing Pseudomonas aeruginosa strains isolated from burn patients in Ahwaz, Iran. Diagn Microbiol Infect Dis 2008; 60:125-8.
17
Ekrami A, Kalantar E. Bacterial infections in burn patients at a burn hospital in Iran. Indian J Med Res 2007; 126:541.
18
Shakibaie M, Adeli S, Nikian Y. Emergence of ciprofloxacin resistance among Pseudomonas aeruginosa isolated from burn patients. Iran J Med Sci 2015; 26:155-9.
19
Lari AR, Alaghehbandan R, Akhlaghi L. Burn wound infections and antimicrobial resistance in Tehran, Iran: an increasing problem. Ann Burns Fire Dis 2005; 18:68.
20
Adabi M, Talebi TM, Arbabi L, Afshar M, Fathizadeh S, Minaeian S, et al. Determination of antibiotic resistance pattern of Pseudomonas aeruginosa strains isolated from patients with burn wounds. J Ardabil Univ Med Sci 2015; 15:66-74.
21
Dohar JE, Kenna MA, Wadowsky RM. In vitro susceptibility of aural isolates of Pseudomonas aeruginosa to commonly used ototopical antibiotics. Am J Otol 1996; 17:207-9.
22
Innes ME, Umraw N, Fish JS, Gomez M, Cartotto RC. The use of silver coated dressings on donor site wounds: a prospective, controlled matched pair study. Burns 2001; 27:621-7.
23
ORIGINAL_ARTICLE
Comparison of the Effects of Parenting Behavioral Management Training (Based on Functional Behavior Assessment Approach), Neurofeedback and Drug Therapy on Attention, and Focus, Behavioral Problems, and Social-Emotional Adjustment in Children with Attention Deficit / Hyperactivity Disorder
Introduction: Children have certain stages of development throughout their lives. Some children, for various reasons, are unable to successfully pass these stages and meet their expectations and developmental tasks in a natural way that results in social, emotional, The purpose of the present study was to investigate the effects of parental behavioral management training interventions (FBA), neurofeedback, and drug therapy on attention and concentration, behavioral problems, and emotional-social adjustment in children with attention deficit / hyperactivitywas disorder.Methods: The study was quasi-experimental with pre-test and post-test with control group. A sample of 80 individuals was randomly assigned into two experimental and control groups by purposeful and voluntary random sampling. For these subjects, the Parent Behavioral Management Training Package, Roswell et al. (1956) Continuous Performance Test, Sinn and Singh's (1993) Student Adaptation and Achenbach Child Behavior Checklist were completed in the pre-test and post-test stages. In this study, descriptive and inferential statistics calculations of multivariate analysis of covariance were analyzed using the twenty-second version of SPSS software version 12.Results: The results showed that the efficacy of the intervention approach was more than the parent and neurofeedback behavioral management training in reducing the problems of overactive children in the three areas under study, respectively. (001/0> P)Conclusion: Behavioral management training of parents, neurofeedback and drug therapy had a significant effect on enhancing the experimental group's improvement.
https://mjms.mums.ac.ir/article_18522_d41d8cd98f00b204e9800998ecf8427e.pdf
2018-01-21
10.22038/mjms.2021.18522
Parent Behavioral Management Training
Functional Behavior Assessment Approach
Neurofeedback
Drug therapy
Attention and Focus
Social Emotion Adaptation
Child Behavioral Problems
Mahboobeh
Omidinejad
m12302460@gmail.com
1
PhD educational Psychology, college of human science, Saveh Branch, Islamic Azad University, Saveh, Iran
AUTHOR
Jacenthe
salibi
jacenthe.salibi@gmail.com
2
Associate professor department of educational psychology Institute for Humanities and Cultural Studies, Tehran, Iran (Corresponding Author (
LEAD_AUTHOR
Hooman
namvar
hooman.namvar@gmail.com
3
assistant professor department of health psychology, college of human science, Saveh Branch, Islamic Azad University, Saveh, Iran
AUTHOR