medical journal of mashhad university of medical sciences
1735-4013
2008-2673
54
2
2011
06
22
Investigation of Diagnostic Values of hsCRP in Pleural Fluid for Differentiation Tuberculosis and Malignant Pleural Effusion
Pulmonary& TB Research Center
69
74
FA
Mohammad Reza
Parizadeh
Associate professor of biochemistry, Mashhad University of Medical Sciences, Mashhad, Iran
Fariba
Rezaeetalab
Assistant professor of pulmonology, Mashhad University of Medical Sciences, Mashhad, Iran
rezaeitalabf1@mums.ac.ir
Ahmad
Marami
Resident of Internal Medicine,Mashhad University of Medical Sciences, Mashhad, Iran
10.22038/mjms.2011.5347
Introduction <br />Pleural effusion is one of the most common and important complications in pulmonology. When the absorption of pleural fluid is less than its secretion, effusion happens and diagnosis between TB and malignant pleural fluid is important. C reactive protein with high sensivity(hsCRP) is secreted by tissue when inflammations is present. The aim of this study was hsCRP[S1] evaluation could help to[S2] differentiate between TB and malignant pleural effusion <br />Materials and Methods <br />100 patients with TB or Malignant pleural effusion who referred to Emam Reza hospital, Mashhad in 2009 underwent thoracocentesis; then hsCRP with photometry methods were analyzed[S3]. All data were analyzed by SPSS 11 and cutoff point for hsCRP with ROC curve was found. <br />Result <br />Mean age was 53.41 years 19.63 SD. Mean concentration of hsCRP was 9.53 (mg/lit) with SD 5.78 (mg/lit). hsCRP concentration in TB group was13.6±5.6 and in malignant pleural effusion group was 6.00±3.93 (mg/lit). They had[S4]significant different with statistical analysis (P<0.001). Sensitivty of hsCRP to differentiate between TB and malignancy with cutoff point of 8.35(mg/lit) is 92% and specificity is 78%. They had significant different with statistical analysis [S5](P<0.001). <br />Conclusion <br />hsCRP cloud help us to differentiate between TB and malignant pleural effusion.
Malignancy,Pleural Effusion,Tuberculosis
https://mjms.mums.ac.ir/article_5347.html
https://mjms.mums.ac.ir/article_5347_080b96a2584e55192e6d73caf7cf5268.pdf
medical journal of mashhad university of medical sciences
1735-4013
2008-2673
54
2
2011
06
22
Comparison of Temporary Dialysis Catheter and A-V Fistula Use at the Time of Starting Chronic Hemodialysis among End-Stage Renal Diseases Patients
75
79
FA
Seyed Seifollah
Beladi , Mousavi
Assistant Professor of Nephrology, Jundishapur University of Medical Sciences, Ahvaz, Iran
mrt_tamadon@yahoo.com
Fatemeh
Hayati
Assistant Professor of Nephrology, Jundishapur University of Medical Sciences, Ahvaz, Iran
Iraj
Neseri
Assistant Professor
Of Surgery, Jundishapur University of Medical Sciences, Ahvaz, Iran
Abbas Ali
Zeraati
Assistant Professor
Of Nephrology,
Mashhad University of Medical Sciences, Mashhad, Iran
zeraaty@mums.ac.ir
10.22038/mjms.2011.5348
Introduction <br />The preferred type of access for chronic hemodialysis (HD) is an Arterio-Venous (A-V) Fistula. However most of the ESRD patients does not have a mature fistula at the time of starting HD due to late referral to the nephrologists so the managing physicians have to use temporary catheters with high rate of complications. <br />Materials and Methods <br />In a retrospective study we determined and compared the prevalence of temporary catheters or A-VFistula use at the time of starting chronic HD from November 1995 to June 2009. We have divided our patients in three different groups. Group A: HD patients between 1995-2005, Group B: HD patients between 2006-2007, and Group C: HD patients after 2007. <br />Results <br />A total of 473 ESRD patients (288 male, 185 female; mean age, 55.8± 16.4 years) were included in the study. Causes of ESRD were HTN 34.1%, DM 20. 08%, glomeronephritis 9.72%, obstructive uropathy 8.46%, ADPKD 5.92%, and unknown 21.77%. Overall the prevalence of temporary catheters and A-V Fistula use were 86.5 and 13.5 percent. But the prevalence was different in the studied groups: group A (93.6% and 6.4%), in group B (85.0% and 15.0%) and in group C (67.5% and 29. 5%) respectively. There was a significant increase in A-V Fistula use after 2005 (p=0.00) and especially after 2007 (p=0.000). <br />Conclusion <br />Although there was a significant increment in the A-V Fistula use, it is not still enough and general physicians, nurses and chronic kidney disease patients have to be educated about the benefits of early A-V Fistula creation.
Arterio-Venous Fistula,hemodialysis,Temporary Dialysis Catheter
https://mjms.mums.ac.ir/article_5348.html
https://mjms.mums.ac.ir/article_5348_21e27d799ea585a21687df965b332ddc.pdf
medical journal of mashhad university of medical sciences
1735-4013
2008-2673
54
2
2011
06
22
A Comparison of Serum Level of Selenium in Women with Preeclampsia and Normal Pregnant Women
80
85
FA
Neda
Davaryari
General Physician, Mashhad University of Medical Sciences, Mashhad, Iran
Ramin
Razavi Panah
General Physician, Mashhad University of Medical Sciences, Mashhad, Iran
Safoura
Homayoon Mehr
General Physician, Mashhad University of Medical Sciences, Mashhad, Iran
Homa
Oskouiyan
Assistant Professor of
Gynecology, Mashhad Islamic Azad University, Mashhad, Iran
Marzieh
Mohajeri
Assistant Professor of
Gynecology, Mashhad Islamic Azad University, Mashhad, Iran
Nayereh
Ghomian
Associated Professor of Gynecology, Mashhad
University of Medical Sciences,
Mashhad, Iran
Seyed Mohsen
Ghasemi
MPH, Statistics, Mashhad Islamic Azad University, Mashhad, Iran
10.22038/mjms.2011.5349
Introduction <br />Preeclampsia is a common complication of pregnancy with the prevalence of 2-7% which increases fetal-maternal mortality. Despite many researches in this field, the etiology of preeclampsia is still unknown and different theories are suggested. Recently the role of deficiency of trace elements is emphasized. Selenium is one of the trace elements which as an antioxidant play an important role in protection of endothelial cells of blood vessel with counterbalancing of oxygen free radicals. The aim of this study was to compare serum level of selenium in women with preeclampsia and normal pregnant women. <br />Materials and Methods <br />This cohort study was performed on 35 women with severe preeclampsia as case group and 30 normal pregnant women as control group in Emam Reza Hospital during 2007-2009. Two groups were matched in terms of maternal age, gestational age, and BMI. Serum level of selenium was measured by spectrophotometer with method of atomic absorption. Data was analyzed with SPSS software version 18 and T-student test. P≤0.05 was considered statistically significant. <br />Results <br />The mean serum level of selenium was significantly decreased in preeclamptic women compared to the healthy pregnant women (P<0.05). In preeclampsia group, pregnancy outcomes were worse in women with lower selenium level. <br />Conclusion <br />This study showed that severe preeclampsia is related with decreased concentration of selenium; early measurement of this element can be useful for early prediction of preeclampsia.
Normal pregnancy,Preeclampsia,Selenium
https://mjms.mums.ac.ir/article_5349.html
https://mjms.mums.ac.ir/article_5349_ec89a4d634f2b80adea01b0e8b91e620.pdf
medical journal of mashhad university of medical sciences
1735-4013
2008-2673
54
2
2011
06
22
Opium Abuse among Patients with Chronic Physical Pain as a Misleading Cause in Addiction Treatment Center
83
93
FA
Seyed Reza
Saeidian
Assistant professor of Physical Medicine and Rehabilitation, Jundishapur university of Medical sciences, Ahvaz, Iran
Soraya
Ashrafizadeh
MPH &Lecturer in public health, Jundishapur university of Medical Sciences, Ahvaz, Iran
Siroos
Pakseresht
Assistant professor of psychiatry, Jundishapur University of Medical sciences, Ahvaz,Iran
Mehdi
saiiah bargard
Assistant professor of psychiatry, Jundishapur University of Medical sciences, Ahvaz,Iran
sayah_bargard@hotmail.com
10.22038/mjms.2011.5350
Introduction <br /> <br />Chronic non-cancer pain has been considered as causes of Opium addiction in human beings. The knowledge of its incidence as an initial reason for Opium consumption among Opium addict people may affect a) addiction prevention plans, b) addiction treatment programmes and even 3) educational goals for training medical students. Therefore,this study aimed to determine this incidence among Opium addict people referred to an addiction treatment center. <br /> <br />Materials and Methods <br /> <br />This is a cross sectional study which was performed in Ahwaz during 2006-2008.First, a pilot study was carried out in which the study sample size was calculated. Participants were evaluated by physical examination, pain scaling via VAS, physical examination and psychological interview based on DSM4 criteria and SCL90 questionnaire. The obtained data were analyzed by descriptive analysis of SPSS and χ square test. <br /> <br />Results <br /> <br />Finally, 21 patients out of 224 participants were found to suffer from a type of chronic physical pain before Opium addiction. Psychological abnormalities were more frequent in pain suffered patients (p<0.007). <br /> <br />Conclusion <br /> <br />There were some people who seek for getting rid of physical pain. But, they were deviating to a street drug abuse status. This issue should be considered in prevention and treatment of addiction.
Addiction treatment,Chronic physical pain,Drug abuse
https://mjms.mums.ac.ir/article_5350.html
https://mjms.mums.ac.ir/article_5350_f8485b68bc8358b552aadc9ba6373abd.pdf
medical journal of mashhad university of medical sciences
1735-4013
2008-2673
54
2
2011
06
22
The Outcome of Transanal Anorectal Myectomy in the Patients with Ultrashort_Segment Hirschsprung`s Disease
94
99
FA
Marjan
Joudi
Assistant professor of Pediatric Surgery, Mashhad University of Medical Sciences, Mashhad, Iran
Mehran
Hiradfar
AssociatedProfessor of Pediatric Surgery, Mashhad University of Medical Sciences, Mashhad, Iran
Mehdi
Fathi
Assistant professor of Anesthesia, Mashhad university of Medical Sciences, Mashhad, Iran
Mona
joudi
Medical doctor
10.22038/mjms.2011.5351
Introduction <br />Anorectal myectomy and anal dilation under anesthesia could be an effective way in the treatment of patients with ultrashort_segment Hirschprung.In this article we studied [S1]the outcomes of anorectal myectomy. <br />Materials and Methods <br />Our study group was [S2]61 patients with the disease who had reffered to SHEIKH hospital from the second half of 1386 to the first half of 1388. Barium enema and anorectal myectomy was performed in all patient[S3].Follow up after myectomy was in the second week after surgery and then monthly[S4].For the complications and results, patients were also divided in to 3 groups based on the presence or absence of ganglion cell in the muscular resectal region,and the results were compared in each [S5]group. <br />Results <br />Bleeding, infection of the operation zone, sepsis, entrocolitis, and anal stenosis was not observed in any patient after surgery. 4 patients had gas incontinence and 3 had fecal incontinence after surgery which was cured in 3-6 months with bio-feedback orders. 40 patients (87.5%) had complete remission after surgery and 2(4.17%) had partial remission and 4(8.33%) had no remission at all. Based on these results, there is no relation between gender, complications of surgery and the results of surgery. <br />Conclusion <br />Anorectal myectomy could be an effective treatment strategy for patients with following situations: absence of anatomical abnormalities-[S6]chronic constipation in spite of medical treatment-[S7]absence of transitional zone in barium enema-[S8]failure of anorectal reflex relaxation with rectal distention in anorectal manometry.
Hirschprung disease,Trans anorectal myectomy,ultrashort segment
https://mjms.mums.ac.ir/article_5351.html
https://mjms.mums.ac.ir/article_5351_5663517d61c80a1b4781137b5628e2d9.pdf
medical journal of mashhad university of medical sciences
1735-4013
2008-2673
54
2
2011
06
22
A Study of Two Months Walking Exercise on Serum Lipoprotein and Body Mass Index in Obese Girls
100
104
FA
Nasim
Habibzadeh
MSc in Physiology, Azad Islamic University, Rasht, Iran
Farhad
RahmaniNia
Professor ofPhysiology, Azad Islamic University, Rasht, Iran
frahmani2001@yahoo.com
10.22038/mjms.2011.5352
Introduction <br />Obesity, a public health problem is growing [S1]in prevalence over the recent decade. One morbidity[S2] associated with obesity is cardiovascular disease (CVD) which is invariably related to dyslipidaemia. The purpose of the present study is to examine the effect of walking exercise in order to reduce the risk of (CVD) in sedentary obese girls. <br />Materials and Methods <br />Twenty untrained obese (BMI>30) girls with age 22.00 ± 1.50 years volunteer took [S3]place in this research and then they were randomly divided in two groups (Control: n=10 Experimental: n=10). At first and after 2 months HDL-c, LDL-c and BMI were assessed[S4]. Then the experimental group started to do exercise programme. The data by[S5] unpaired- t-test at the level of pResults <br />The study finding showed that reduced [S6]BMI (p=0.001), LDL-c (p=0.006)significantly decreased but HDL-c (p=0.004) significantly increased in exercise[S7] group. <br />Conclusion <br />This study demonstrated that a programme of regular physical activity such as walking exercise significantly can[S8] change the lipoprotein's metabolism in body and reduce the risk of (CVD) in obese girls.
Body mass index,Obese Girls,Serum Lipoprotein,Walking exercise
https://mjms.mums.ac.ir/article_5352.html
https://mjms.mums.ac.ir/article_5352_4ebda25352c6a30498830c3f74440562.pdf
medical journal of mashhad university of medical sciences
1735-4013
2008-2673
54
2
2011
06
22
Brain Computed Tomography Scan in Meningitis Patients with Deterioration Of Consciousness
105
112
FA
Ashraf
Tavanaee Sani
AssociateProfessor of Infectious Diseases
Mashhad University of Medical Sciences, Mazandaran, Iran
Donya
Farokh
Associate Professor of Radiology,Mashhad University of Medical Sciences,Mashhad, Iran
farrokhd@mums.ac.ir
Hamidreza
Naderi
Assistant Professor of Infectious Diseases
Mashhad University of Medical Sciences, Mashhad, Iran
naderihr@mums.ac.ir
Habibollah
Esmaeili
Associate Professor of Biostatistics,Mashhad University of Medical Sciences,Mashhad, Iran
Simin
Abasian
Assistant of Infectious Diseases,Mashhad University of Medical Sciences,Mashhad, Iran
Khosro
Mohamadi
Assistant of Infectious Diseases,Mashhad University of Medical Sciences,Mashhad, Iran
mohamadikh@mums.ac.ir
10.22038/mjms.2011.5353
Introduction <br />Due to life-threatening complication of LP in patients with deterioration of consciousness due to meningitis (=brain herniation) the LP procedure safety without brain CT scan is debated. <br />Materials and Methods <br />This descriptive cross-sectional study was done on patients suspected of meningitis with decreased consciousness referred to the infectious emergency of Emam Reza Hospital, Mashhad, Iran from April 2006 to March 2008. All patients underwent physical examination (neurologic and ophthalmoscopic) of the patients by residents of infectious diseases. Data (results of physical examination, neurologic, ophtalmoscopic, brain CT scan and LP) were collected. Then statistical analysis was performed with SPSS software and descriptive statistical methods. <br />Results <br />136 patients were evaluated. The mean age of patients was 43.88±21.185 years and 58.5% (24) of the cases were male. The result of brain CT was normal in 53.7%. The most frequent abnormal brain CT results were hypodencity lesions (12%). <br />2.4 % (1) of patients had abnormal CT-Scan with space occupying lesion with mass effect and midline shift, and final diagnosis was brain abscess due to chronic mastoiditis. <br />Conclusion <br />This study showed that abnormal finding of brain CT-Scan in adult meningitis with loss of consciousness is approximately 50% and mass effect was seen in 2.4% of patients
Abnormal consciousness,Brain CT Scan,LP,Meningitis
https://mjms.mums.ac.ir/article_5353.html
https://mjms.mums.ac.ir/article_5353_0adcd6d2fe852d4d3124827b89b61b8d.pdf
medical journal of mashhad university of medical sciences
1735-4013
2008-2673
54
2
2011
06
22
Influence of various factors on Response to Streptokinase therapy for acute myocardial Infarction
113
119
FA
Mashalah
Dehghani
Professor of Cardiology, Mashhad University of Medical Science,Mashhad, Iran
Ali
Eshraghi
0000-0002-3642-3553
Cardiologist,Mashhad University of Medical Sciences,Mashhad, Iran
eshraghia@mums.ac.ir
Mohamad Taghi
Shakeri
0000-0002-8287-9594
Associate Professor of Biostatistics,Mashhad University of Medical sciences,Mashhad, Iran
shakerimt@mums.ac.ir
Azadeh
Fallah Rastgar
Cardiologist,Mashhad University of Medical Sciences,Mashhad, Iran
Golnaz
Hoshmand
Cardiologist,Mashhad University of Medical Sciences,Mashhad, Iran
10.22038/mjms.2011.5354
Introduction <br /> <br />Prevalence of ischemic heart diseases, especially acute myocardial infarction and its incidence in lower age has increased and treatment during the acute phase of myocardial infarction plays an important role in the prognosis and quality of life. In our study, we aimed to evaluate the effects of streptokinase on treatment of acute myocardial infarction based on different variables. <br />Materials and Methods <br />In our study, we evaluated patients with acute myocardial infarction who received streptokinase. Information obtained from patients based on patient examination, ECG findings (before and after drug administration) and the results of relevant laboratory tests, then entered in the relevant checklist. Criteria for response to drug were reduced chest pain with at least 50 percent reduction in ECG ST Elevation in electrocardiography taken 30 or 90 minutes after the Streptokinase therapy <br />Results <br />Relation between age (P<0.001), LDL (0.001), diabetes mellitus (P=0. 01), location of MI (P=0.001), Killip Class (P<0.001), patients referring delay (P<0.001) and the effect of streptokinase were significant. While gender, hypertension, smoking, previous ischemic heart disease, time of symptoms onset and type of streptokinase didn’t affect significantly the response to streptokinase. <br />Conclusion <br />Considering our results, patients with acute MI less than 30 years and more than 80 years, diabetics, LDL more than 100mg/dl, extensive anterior MI, new LBBB, Killip Class 3 or 4 and delay of referring more than 12 hours predict poor response streptokinase, and may benefit more from early invasive strategy than thrombotic therapy.
Acute myocardial infarction,Risk factors,Streptokinase,Thrombolytic therapy
https://mjms.mums.ac.ir/article_5354.html
https://mjms.mums.ac.ir/article_5354_74348458b8b2c0f2f8e52872796cb79c.pdf
medical journal of mashhad university of medical sciences
1735-4013
2008-2673
54
2
2011
06
22
A Case Report of Primary Glomus Tumour of Stomach in a 59 Year Old Man
120
124
FA
Ahmad
Khosravi
Associate professor of Internal Medicine,Mashhad University of Medical Sciences, Mashhad, Iran
khosravia@mums.ac.ir
Mehrdad
Katebi
Pathologist
Hosein
Shabahang
Assistant professor of General Surgery,Mashhad University of Medical sciences, Mashhad, Iran
Bahram
Memar
Assistant professor of Pahology, MashhadUniversity of Medical sciences, Mashhad, Iran
Mitra
Ahadi
Resident of gastrointestinal and liver disease fellowship,Mashhad University of Medical Sciences, Mashhad, Iran
mitraa@mums.ac.ir
Elham
Mokhtari
Resident of gastrointestinal and liver disease fellowship,Mashhad University of Medical Sciences, Mashhad, Iran
10.22038/mjms.2011.5355
Introduction <br />Primary gastric Glomus tumour is rare and much less frequent than gastrointestinal stromal tumors(GIST).a[S1]t least 150 of them have been reported in articles, but no one had been published in Iran. <br />[ <br />Case report <br />Patient was a 59 years old man with the chief complains of sense of epigastric fullness after meal. Endosonography showed a hypoechoic mass in muscularis mucosa with 29×14 mm dimentions. p[S2]atient underwent wedge resection of gastric tumour. In microscopy, sheets and nodules of round to polyhedral uniform cells with bland round to oval nuclei in the background of branched hemangiopericytoma-like vascular stroma with hyalinised wall were seen. Smooth Muscle Actin, desmin, chromogranin and CD117 were determined immunohistochemicaly, the first marker was positive and the reminders were negative. <br />Conclusion <br />Primary gastric Glomus tumour is essentially a benign neoplasm[S3], in order to prevent unnecessary radical surgery, its differentiation from others malignant lesions is mandatory.
Glomus tumour,Gastric,Glomangioma
https://mjms.mums.ac.ir/article_5355.html
https://mjms.mums.ac.ir/article_5355_dc5138980f55f99f6b6190f46fdf440d.pdf