Medical Journal of Mashhad university of Medical Sciences

Medical Journal of Mashhad university of Medical Sciences

Relational Study of Clinical Findings and Renal Pathology in Systemic Lupus Erythematosus Patients

Document Type : Research Paper

Authors
Nayyereh Saadati 1
Maryam Hami 2
Ataollah Behroz Aghdam 3
Baharam Naghibzadeh 4
1 Associate Professor of Rheumatology, Mashhad University of Medical Sciences, Mashhad, Iran
2 Assistant Professor of Nephrology, Mashhad University of Medical Sciences, Mashhad, Iran
3 - Professor of Nephrology, Mashhad University of Medical Sciences, Mashhad, Iran
4 General Practitioner, Mashhad University of Medical Sciences, Mashhad, Iran
10.22038/mjms.2012.157
Abstract
Introduction
Renal biopsy plays a very important role in diagnosis, and treatment of patients with systemic lupus erythematosus (SLE). The purpose of our study was to assess the role of renal biopsy in determining the prognosis of SLE.
 Materials and Methods
In this prospective review, which was pereformed in the Department of Internal Medicine of Gheam Medical Center, we studied 34 SLE patients for 5 years. After acquiring medical history and a routine general physical examination, clinical and serological characteristics of all patients were consecutively collected in questionnaires.
Results
Of 34 patients, 32 were female and 2 were male. The median age of patients was 25.12±12.05 years. All of them had lupus nephritis. The most common type of renal pathology was class IV lupus nephritis. Patients with class IV lupus nephritis had the worst prognosis.
Conclusion
Age, sex and renal pathology prevalence in the present study is similar to other studies. Lupus nephritis remains a strong predictor for development of end-stage renal disease (ESRD) and death in patients with SLE.
Keywords
Lupus nephritis
Renal
systemic lupus erythematosus
Medical Journal of Mashhad university of Medical Sciences
Volume 55, Issue 4 - Serial Number 4
January 2013
Pages 218-224