Effect of Swimming Training along with Omega-3 Intake on Irisin and Body Composition in Obese Girls with Down Syndrome

Document Type : Research Paper


1 Department of Physical Education and Sport Sciences, East Tehran Branch, Islamic Azad University, Tehran, Iran.

2 member of scientific board Islamic Azad University East Tehran Branch

3 Faculty of Physical Education and Sport Sciences, Central Tehran Branch, Islamic Azad University, Tehran, Iran.


Introduction: Neurological, metabolic and physical problems such as cardiovascular insufficiency are of the most important causes of deaths in children with Down syndrome. The aim of this study was to evaluate omega-3 intake along with eight weeks of swimming training on irisin and body composition in obese girls with Down syndrome.
 Materials and Methods: In this semi-experimental study, 18 girls with Down syndrome (12 ±2 years and 22± 1.3 kg / m2) were randomly divided into two groups of exercise training and exercise training + supplements. The subjects participated in twenty-four sessions of swimming training with an intensity of 45-65 percent maximal heart rate and consumption of 300 mg omega-3 capsule (exercise group + supplement) for 8 weeks. Blood samples were taken 24 hours before the first training session and 48 hours after the last training session. Data were analyzed using repeated measures ANOVA. P≤ 0.05 was considered statistically significant.
 Results: The results showed that in the supplementation group, the levels of serum irisin and muscle mass significantly increased after 8 weeks (P <0.05) and the amount of fat significantly decreased (P <0.05). 
Conclusion: It seems that swimming training and omega-3 supplement in children with Down syndrome can reduce the risk of cardiovascular diseases and improve many of their motor limitations by affecting body composition.
 Funding: This research was funded by East Tehran Branch, Islamic Azad University, Tehran, Iran.