Effect of Swimming Training along with Omega-3 Intake on Irisin and Body Composition in Obese Girls with Down Syndrome

Document Type : Research Paper

Authors

1 Department of Physical Education and Sport Sciences, East Tehran Branch, Islamic Azad University, Tehran, Iran.

2 member of scientific board Islamic Azad University East Tehran Branch

3 Faculty of Physical Education and Sport Sciences, Central Tehran Branch, Islamic Azad University, Tehran, Iran.

Abstract

Introduction: Neurological, metabolic and physical problems such as cardiovascular insufficiency are of the most important causes of deaths in children with Down syndrome. The aim of this study was to evaluate omega-3 intake along with eight weeks of swimming training on irisin and body composition in obese girls with Down syndrome.
 Materials and Methods: In this semi-experimental study, 18 girls with Down syndrome (12 ±2 years and 22± 1.3 kg / m2) were randomly divided into two groups of exercise training and exercise training + supplements. The subjects participated in twenty-four sessions of swimming training with an intensity of 45-65 percent maximal heart rate and consumption of 300 mg omega-3 capsule (exercise group + supplement) for 8 weeks. Blood samples were taken 24 hours before the first training session and 48 hours after the last training session. Data were analyzed using repeated measures ANOVA. P≤ 0.05 was considered statistically significant.
 Results: The results showed that in the supplementation group, the levels of serum irisin and muscle mass significantly increased after 8 weeks (P <0.05) and the amount of fat significantly decreased (P <0.05). 
Conclusion: It seems that swimming training and omega-3 supplement in children with Down syndrome can reduce the risk of cardiovascular diseases and improve many of their motor limitations by affecting body composition.
 Funding: This research was funded by East Tehran Branch, Islamic Azad University, Tehran, Iran.
 

Keywords

References

  1. Mirqaemi T S, Sharifi Daramadi P, Afrouz G A. An Investigation on the Effect of Family-Centered Psychological
    Interventions on the Verbal Ability of Children with Down Syndrome. jcmh. 2018; 5 (3) :126-136.
    2. Barlow GM, Chen XN, Shi ZY, Lyons GE, Kurnit DM, Celle L, Spinner NB, Zackai E, Pettenati MJ, Van Riper AJ,
    Vekemans MJ, Mjaatvedt CH, Korenberg JR. Down syndrome congenital heart disease: a narrowed region and a
    candidate gene. Genet Med. 2001 Mar-Apr;3(2):91-101. PubMed PMID: 11280955.
    3. González-Agüero A, Ara I, Moreno LA, Vicente-Rodríguez G, Casajús JA. Fat and lean masses in youths with Down
    syndrome: gender differences. Res Dev Disabil. 2011 Sep-Oct;32(5):1685-93. doi: 10.1016/j.ridd.2011.02.023. Epub
    2011 Mar 24. PubMed PMID: 21435834.
    4. Reinehr T, Dobe M, Winkel K, Schaefer A, Hoffmann D. Obesity in disabled children and adolescents: an
    overlooked group of patients. Dtsch Arztebl Int. 2010 Apr;107(15):268-75. doi: 10.3238/arztebl.2010.0268. Epub 2010
    Apr 16. PMID: 20458368; PMCID: PMC2864441.
    5. Asim A, Kumar A, Muthuswamy S, Jain S, Agarwal S. "Down syndrome: an insight of the disease". J Biomed Sci.
    2015 Jun 11;22(1):41. doi: 10.1186/s12929-015-0138-y. PMID: 26062604; PMCID: PMC4464633.
    6. Mahy J, Shields N, Taylor NF, Dodd KJ. Identifying facilitators and barriers to physical activity for adults with
    Down syndrome. J Intellect Disabil Res. 2010 Sep;54(9):795-805. doi: 10.1111/j.1365-2788.2010.01308.x. PubMed
    PMID: 20712696.
    6. Villarroya F. Irisin, turning up the heat. Cell Metab. 2012 Mar 7;15(3):277-8. doi: 10.1016/j.cmet.2012.02.010.
    PubMed PMID: 22405065.
    8. Boström PA, Fernández-Real JM, Mantzoros C. Irisin in humans: recent advances and questions for future research.
    Metabolism. 2014 Feb;63(2):178-80. doi: 10.1016/j.metabol.2013.11.009. Epub 2013 Nov 19. PubMed PMID:
    24342075.
    9. Martinez Munoz, I. Y., Camarillo Romero, E., & Garduno Garcia, J. J. (2018). Irisin a Novel Metabolic Biomarker:
    Present Knowledge and Future Directions. International journal of endocrinology, 2018, 7816806.
    doi:10.1155/2018/7816806
    10. Ramezani A, Djalali M. Effects of Administration of Omega-3 Fatty Acids with or without Vitamin E on Body
    Composition in Patients with Coronary Artery Disease: A Clinical Trial. J Mazandaran Univ Med Sci. 2016; 25 (133)
    :25-36. )Farsi(
    11. Paul Y, Ellapen TJ, Barnard M, Hammill HV, Swanepoel M. The health benefits of exercise therapy for patients
    with Down syndrome: A systematic review. Afr J Disabil. 2019 Oct 23; 8:576. doi: 10.4102/ajod.v8i0.576. PMID:
    31745461; PMCID: PMC6852506.
    12. Charmas M, Gromisz W. Effect of 12-Week Swimming Training on Body Composition in Young Women. Int J
    Environ Res Public Health. 2019 Jan 26;16(3):346. doi: 10.3390/ijerph16030346. PMID: 30691153; PMCID:
    PMC6388213.
    13. Saremi A, Rajabi M. Effect of resistance training and omega-3 supplementation on metabolic parameters and antimullerian hormone level in women with polycyctic ovarian syndrome. pajoohande. 2016; 21 (3) :114-121. )Farsi(
    14. Huang SY, Yang HT, Chiu CC, Pariante CM, Su KP. Omega-3 fatty acids on the forced-swimming test. J Psychiatr
    Res. 2008 Jan;42(1):58-63. Epub 2006 Oct 30. PubMed PMID: 17070845.
    15. Zmijewski PA, Gao LY, Saxena AR, Chavannes NK, Hushmendy SF, Bhoiwala DL, Crawford DR. Fish oil
    improves gene targets of Down syndrome in C57BL and BALB/c mice. Nutr Res. 2015 May;35(5):440-8. doi:
    10.1016/j.nutres.2015.02.007. Epub 2015 Mar 1. PubMed PMID: 25799055.
    16. Ghasemi A, Momeni M, Sohrabi M. The Effect of Sport Activities on Perceptual-motor Skills among Obese
    Children with Down Syndrome. jrehab. 2015; 16 (2) :168-175. )Farsi(
    17. Sayadinezhad T, Abdolvahab M, Akbarfahimi M, Jalili M, Rafiee S, Baghestani A R. The study of the effect of
    progressive resistance training on functional balance of 8-12 years old children with Down syndrome. mrj. 2013; 7 (1)
    :29-33 )Farsi(
    18. Norheim F, Langleite TM, Hjorth M, Holen T, Kielland A, Stadheim HK, Gulseth HL, Birkeland KI, Jensen J,
    Drevon CA. The effects of acute and chronic exercise on PGC-1α, irisin and browning of subcutaneous adipose tissue
    in humans. FEBS J. 2014 Feb;281(3):739-49. doi: 10.1111/febs.12619. Epub 2013 Dec 10. PubMed PMID: 24237962.
    19. Kim HJ, Lee HJ, So B, Son JS, Yoon D, Song W. Effect of aerobic training and resistance training on circulating
    irisin level and their association with change of body composition in overweight/obese adults: a pilot study. Physiol
    Res. 2016 Jun 20;65(2):271-9. Epub 2015 Oct 8. PubMed PMID: 26447516.
    20. Jung WS, Hwang H, Kim J, Park HY, Lim K. Effect of interval exercise versus continuous exercise on excess postexercise oxygen consumption during energy-homogenized exercise on a cycle ergometer. J Exerc Nutrition Biochem.
    2019 Jun 30;23(2):45-50. doi: 10.20463/jenb.2019.0016. PMID: 31337205; PMCID: PMC6651650.
    21. Wang WY, Ju YH. Promoting balance and jumping skills in children with Down syndrome. Percept Mot Skills.
    2002 Apr;94(2):443-8. PubMed PMID: 12027336.
  2. 22. Villarroya MA, González-Agüero A, Moros T, Gómez-Trullén E, Casajús JA. Effects of whole body vibration
    training on balance in adolescents with and without Down syndrome. Res Dev Disabil. 2013 Oct;34(10):3057-65. doi:
    10.1016/j.ridd.2013.06.015. Epub 2013 Jul 19. PubMed PMID: 23872530.
    24. Dodd KJ, Shields N. A systematic review of the outcomes of cardiovascular exercise programs for people with
    Down syndrome. Arch Phys Med Rehabil. 2005 Oct;86(10):2051-8. Review. PubMed PMID: 16213253.
Medical Journal of Mashhad university of Medical Sciences
Volume 63, Issue 3
July and August 2020
Pages 2342-2349

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