Introduction: Understanding of metabolic and hormonal responses is main principles in each training programs. The purpose of this study was to determine the effect of sprint training on response and adaptation of enzymes, metabolites and hormones of healthy men.
Materials and Methods: This study was semi-experimental research with repeated measures design. In this study, 10 Sprinter in Mazandaran were selected and after it perform the Astrand protocol to speed of 7.1 mph and 2.5 degrees. Then, subjects perform sprint training for 6 weeks to intensity of 60 maximal HR. Finally, ten blood samples was taken at pre and post test.
Results: Statistical analysis showed that HR of subjects was significantly decreased (p<0/05). Also, amounts of testosterone and growth hormone was increased that statistically wasn't significant (p>0/05). In addition, amount of Insulin was significantly decreased (p<0/05). Levels of T3 in serum was significantly decreased (p<0/05) but amount of T4 in during and after of test was significantly increased (p<0/05). Levels of LDH and CPK in serum was significantly increase during training bouts (p<0/05) but amounts of LDH and CPK was decreased after training period.
Conclusion: Six weeks sprint training appear to able increase athletic performance due to changes in profile of hormonal (such as increase in testosteron, GH and T4 and dercreas in insulin) and metabolic adaptations.