Medical Journal of Mashhad university of Medical Sciences

Medical Journal of Mashhad university of Medical Sciences

The effect of rest interval between sets during bouts of eccentric exercise on serum levels of TNF-α in untrained men

Document Type : Research Paper

Authors
Hossein Mohammadi 1
Mohammad Esmaiel Afzalpour 2
Seyed Hossein Abtahi Ievary 3
1 Sport Physiology Dept., University of Birjand, Birjand, Iran(Corresponding Author)
2 Sport Physiology Dept., University of Birjand, Birjand, Iran
3 Medical Dept., University of Gonabad, Gonabad, Iran
10.22038/mjms.2022.21855
Abstract
Introduction
Various studies have demonstrated that different rest Intervals has a significant effect on hormonal, metabolic and cardiovascular responses. This factors can lead to different muscle damage responses.
Material and Method
20 untrained subjects (25.4 ± 0.068 years, height 1.74 ± 0.97 cm and weight 30.8 ± 8.48 kg) in three sessions of eccentric resistance exercise with 24 hours rest between each session Participated in this study. Subjects were divided into 2 groups of 10 subjects who performed 50 eccentric contractions with number of 5 sets, 10 repetitions, and the interset rest interval 1 and 3 minutes with 85% of one repetition maximum (1RM). Alpha necrosis tumor factor, were measured immediately before , immediately after each session and 24 hours after the last training session. Variance analysis with repeated measurment and Bonferroni post- hoc test were used to statistical analysis of data.
Results
Alpha necrosis tumor factor in the immediately after each training session and 24 hours after the last training session in 2 groups significantly increased (P <0.05), but no significant difference in All dependent variable was found in 2 groups at different time points.
Conclusion
The repetition of eccentric exercise for three consecutive days causes muscle damage that can be a factor influencing the immune system and causing inflammatory responses in untrained individuals independent of manipulating the interset rest intervals.
Keywords
eccentric exercise
muscle damage
inflammatory markers
rest intervals
Alpha necrosis tumor factor
Medical Journal of Mashhad university of Medical Sciences
Volume 65, Issue 5
May and June 2022