Medical Journal of Mashhad university of Medical Sciences

Medical Journal of Mashhad university of Medical Sciences

The effect of 12 weeks of circuit resistance training on hypothalamic-pituitary-thyroid axis levels in middle-aged women with hypothyroidism

Document Type : Research Paper

Authors
Ashraf Amini
Zahra Mirakhori
Department of physical education, Amir Kabir University of Technology, Tehran, Iran.
10.22038/mjms.2020.26642
Abstract
Hypothyroidism is one of the most common chronic diseases among women. Although exercise has positive effects on the levels of hormones of the hypothalamic-pituitary-thyroid axis, very limited research has been conducted in this field. herefore, 40 women (age 37 ± 4.73 years, weight 67 ± 5.46 kg, and height 168 ± 6.91 cm) with hypothyroidism were randomly divided into two groups: exercise and control after filling out a personal consent form. The training group participated in circuit resistance training four days a week at an intensity of 65 to 80% of 1RM for 12 weeks, and the control group continued their normal lives. Blood samples were taken from the subjects' brachial veins 48 hours before and after the last training session and sent to the laboratory to examine changes in T3, T4, and TRH hormones. The t-test was used to analyze the data. The results showed that T3 and T4 levels in the exercise group increased significantly compared to the control group (P=0.000, P=0.001, respectively), and TRH levels in the exercise group decreased significantly compared to the control group (P=0.021). As a result, it seems that 12 weeks of regular exercise has a positive effect on regulating the hypothalamic-pituitary-thyroid axis and can be recommended as an adjunct treatment method along with the use of medical drugs for hypothyroidism to patients with it.
Keywords
Circuit training
T3
T4
and TRH
Medical Journal of Mashhad university of Medical Sciences
Volume 62, Issue 6
March and April 2020