Medical Journal of Mashhad university of Medical Sciences

Medical Journal of Mashhad university of Medical Sciences

Effect of acute and chronic coenzyme Q10 supplementation on lactate dehydrogenase after exhaustive aerobic activity

Document Type : Research Paper

Authors
Nasser Behpoor 1
Hana seidi 2
1 Associate Professor, Department of Sport Sciences, Razi University, Kermanshah, Iran
2 M.A. graduate in Physical Education, specializing in Exercise Physiology and Physical Activity & Health, Razi University, Kermanshah, Iran
10.22038/mjms.2025.89184.5053
Abstract
The aim of present study was investigating the acute and chronic effects of consuming Coenzyme Q10 supplement on rate of lactate dehydrogenase after exhaustive aerobic activity of Bruce. For this purpose 12 out of 22 players of Omid B’esat Kermanshah football team ranging from 19-21 in age volunteered to take part in this study. The study was conducted in 8 weeks and participants were posited into one situation but into two groups of control (N=12) and experimental (N=12). The experimental group during one session (acute effect) in 8 weeks (chronic effect) consumed 200 milligrams of coenzyme Q10 supplement (2 tablets each100 milligrams) daily. In order to exert muscular damage in subjects, they were tested by exhaustion test. Before and after the Bruce test in all three positons of acute, control, and chronic, 5 cc blood was bled from all subjects’ vein head elbow..The activity of serum total lactate dehydrogenase enzyme was determined by the LHD kit of Bio-System Company and auto-analyzer set (Iranian Alfa Classic). All measurements were done form 9-11.5 pm in the same ventilation and light conditions. The results showed that consuming Coenzyme Q10 after exhaustive aerobic activities (Bruce test) caused a significant decrease of inflammatory markers in subjects’ blood’s lactate dehydrogenase in the acute position. But in the chronic position no significant effect of consuming the supplement on decreasing blood’s lactate dehydrogenase was observed.
Keywords
coenzyme Q10 supplement
lactate dehydrogenase
exhaustive Bruce test
Subjects
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Medical Journal of Mashhad university of Medical Sciences
Volume 68, Issue 6
January and February 2026
Pages 1708-1724