Acute effect of Caffeine and L-carnitine Supplement Administration on Metabolic Rate and Substrate Oxidation during and after high intensity intermittent exercise in active male students

Document Type : Research Paper

Authors

1 MSc in Sport Sciences, Faculty of Sport Sciences, University of Birjand, Birjand, Iran

2 Associate Professor of Physiology of Sport, Faculty of Sport Sciences, University of Birjand, Birjand, Iran

3 Professor of Physiology of Sport, Faculty of Sport Sciences, University of Birjand, Birjand, Iran

Abstract

Introduction
High-Intensity intermittent exercise upon taking supplements containing bioactive compounds result in improving metabolism and fat oxidation .Thus, the aim of this study was to investigate the acute effect of caffeine, L-carnitine, caffeine-L-carnitine (combined) supplements on metabolic rate and substrate oxidation during and after high-Intensity intermittent exercise.
Material and Method
For this purpose, 10 male active students in a randomized double-blind crossover design in four modes of use: - Placebo (3 mg/kg. BW glucose and fructose); Caffeine (6 mg1/kg.BW); - L-carnitine (13 mg/kg. BW); and - caffeine-L-carnitine (6 and 13 mg/kg. BW, respectively.) In each of the four conditions, the subjects engaged in exercise (performing four 30-second Wingate tests (75 g/kg.BW) with a 5-minute rest interval) one hour after supplementation. Respiratory gases were measured before, during and 30 minutes after exercise and were analyzed to calculate metabolic rate (energy expenditure and oxygen consumption) and substrate oxidation (Respiratory Exchange Ratio (RER) and Fat oxidation). One-way ANOVA test was used for statistical analysis.
Results
The delta between the post-pre-test show significant change only in RER (P=0.048), Substrate oxidation (P=0.036) and heart rate (P=0.04). In addition, caffeine consumption was associated with a significant decrease in RER during the recovery period compared to L-carnitine (P=0.015) and placebo (P=0.042). Also, caffeine consumption in comparison with L-carnitine (P=0.008), combined supplement (P=0.037) and placebo (P=0.032) significantly increased Substrate oxidation in the recovery period. Conclusion
Therefore, it is recommended to participants who are looking to offer weight loss or management do high-intensity intermittent exercise upon taking caffeine.

Keywords


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