Stem cell therapy and the Central nervous system diseases: findings, obstacles, and future

Document Type : Review article

Authors

1 - Nanotechnology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

2 Department of Medical Biotechnology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Abstract

Some neurological diseases such as parkinson, stroke, and spinal injury are as a result of cellular loss in the otherwise normal nervous system.  Replacing damaged cells with healthy ones has opened a new hope window to treat or prevent the further disease progression.  Different studies have shown that stem cells can differentiate and replace the lost neurons and glial cells in the central nervous system.  However, the right cell type selection, treatment procedure, the best cell delivery method, and the treatment follow-up are among the major challenges faced this therapeutic vision.  In this review, we have got through significant basic and clinical studies for neurological disease cell therapy to provide a basis for future applications of this therapeutic approach in clinics.  Indeed, continuous and noticeable progress in cell therapy through the basic and clinical investigations will offer new hopes to people suffer from these diseases across the globe.
 

Keywords


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