Background and Aim: Pseudomonas aeruginosa plays an important role in severe infections in burn patients. The sepsis caused by this bacterium is a serious complication of burn infection. The aim of this study was to determine the frequency and antibiotic resistance pattern of Pseudomonas aeruginosa isolated from wounded patients admitted to burn ward in Zahedan. Methods: In this descriptive cross-sectional study, 70 isolates of P. aeruginosa were collected from burn wound samples from Zahedan. After biochemical tests and confirmation of the bacterial strain, antibiotic resistance was determined for nine antibiotics by disk diffusion method according to Clinical Laboratory Standards Institute (CLSI) standard. The minimum inhibitory concentration (MIC) of imipenem, piperacillin tazobactam and ceftazidime was determined by E-test strips. Results: In this study, out of 70 P. aeruginosa isolates, the highest resistance to Trimethoprim /Sulfamethoxazole (84.3%) and cefepime (70.8%) was observed. The lowest resistance to piperacillin/tazobactam (20.8%) and colistin (8.3%) was report. E-test results showed the highest sensitivity to piperacillin/tazobactam. Conclusion: In this study, P. aeruginosa strains showed the least resistance to colistin and piperacillin/tazobactam. These antibiotics could be the main alternative for the treatment of pseudomonas infections caused by burns.
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Jahantigh, M., Tahmasbi, H., & Bakaeiyan, M. (2018). Antibiotic Resistance Pattern of Pseudomonas aeruginosa Strains Isolated from Burn Patients. Medical Journal of Mashhad university of Medical Sciences, 60(6), 1121-1131. doi: 10.22038/mjms.2019.14778
MLA
Mojdeh Jahantigh; Hamed Tahmasbi; Mohammad Bakaeiyan. "Antibiotic Resistance Pattern of Pseudomonas aeruginosa Strains Isolated from Burn Patients", Medical Journal of Mashhad university of Medical Sciences, 60, 6, 2018, 1121-1131. doi: 10.22038/mjms.2019.14778
HARVARD
Jahantigh, M., Tahmasbi, H., Bakaeiyan, M. (2018). 'Antibiotic Resistance Pattern of Pseudomonas aeruginosa Strains Isolated from Burn Patients', Medical Journal of Mashhad university of Medical Sciences, 60(6), pp. 1121-1131. doi: 10.22038/mjms.2019.14778
VANCOUVER
Jahantigh, M., Tahmasbi, H., Bakaeiyan, M. Antibiotic Resistance Pattern of Pseudomonas aeruginosa Strains Isolated from Burn Patients. Medical Journal of Mashhad university of Medical Sciences, 2018; 60(6): 1121-1131. doi: 10.22038/mjms.2019.14778