Evaluation of changes in kidney masses within 15 years

Document Type : Research Paper

Authors

1 Kidney Transplantation Complications Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

2 Student Research Committee, Department of Biostatistics, School of Health, Mashhad University of Medical Sciences, Mashhad, Iran.

3 Student research committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

4 Kidney Transplant Complications Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

Abstract

Objective: kidney cancer has a frequency of 3% in all cancers and this frequence has increased recently. We tried to investigate the prevalence, stage and type of renal tumors within 15 years in Mashhad.
 
Methods & Materials: In this cross-sectional study, the pathologie of patients undergone nephrectomy due to tumor in previous (2001-2002) and recent(2016-2017)years in Imam Reza Hospital in Mashhad, were examined. All records of both groups were reviewed including demographic information and  mass informations such as number, size and type of pathology.
 
Results: Among 145 patients, 45 (31%) were prevoiusly registered in 2001-2002 and 100 (69%) were recently registered in 2016-2017. 71% of new cases and 55.56% of prevoius cases were male and both groups were in second group. There was no significant differences in the frequency distribution of gender (P = 0.07), disease grade (P = 0.75), mass location (P = 0.24), resection type (P = 0.89), lymphovascular invasion (P = 0.74) and extracapsular (P = 0.84) between old and new cases. The final diagnosis in 95% of new cases and 84.4% of old cases was renal cell carcinoma (RCC) and there was a significant difference in the frequency distribution of the final diagnosis between old and new cases (P = 0.02).
 
Conclusion:
This study shows the general pattern and increasing incidence of RCC in Mashhad, which requires further studies to investigate the etiology and risk factors and even eliminate them if possible.

Keywords

References

  1. Miller KD, Goding Sauer A, Ortiz AP, Fedewa SA, Pinheiro PS, Tortolero‐Luna G, Martinez‐Tyson D, Jemal A, Siegel RL. Cancer statistics for hispanics/latinos, 2018. CA: A Cancer Journal for Clinicians. 2018 Nov;68(6):425-45.
  2. Thorstenson A, Bergman M, Scherman-Plogell AH, Hosseinnia S, Ljungberg B, Adolfsson J, Lundstam S. Tumour characteristics and surgical treatment of renal cell carcinoma in Sweden 2005–2010: a population-based study from the national Swedish kidney cancer register. Scandinavian journal of urology. 2014 Jun 1;48(3):231-8.
  3. Adibi M, Karam JA, Wood CG. Reporting geographic and temporal trends in renal cell carcinoma: why is this important?. European urology. 2014 Oct 29;67(3):531-2.
  4. Ferlay J, Colombet M, Soerjomataram I, Dyba T, Randi G, Bettio M, Gavin A, Visser O, Bray F. Cancer incidence and mortality patterns in Europe: Estimates for 40 countries and 25 major cancers in 2018. European journal of cancer. 2018 Nov 1;103:356-87.
  5. Levi F, Ferlay J, Galeone C, Lucchini F, Negri E, Boyle P, La Vecchia C. The changing pattern of kidney cancer incidence and mortality in Europe. BJU international. 2008 Apr;101(8):949-58.
  6. Cai Q, Chen Y, Qi X, Zhang D, Pan J, Xie Z, Xu C, Li S, Zhang X, Gao Y, Hou J. Temporal trends of kidney cancer incidence and mortality from 1990 to 2016 and projections to 2030. Translational Andrology and Urology. 2020 Apr;9(2):166.
  7. Medina-Rico M, Ramos HL, Lobo M, Romo J, Prada JG. Epidemiology of renal cancer in developing countries: Review of the literature. Canadian Urological Association Journal. 2018 Mar;12(3):E154.
  8. Capitanio U, Bensalah K, Bex A, Boorjian SA, Bray F, Coleman J, Gore JL, Sun M, Wood C, Russo P. Epidemiology of renal cell carcinoma. European urology. 2019 Jan 1;75(1):74-84.
  9. Hassanipour S, Namvar G, Fathalipour M, Salehiniya H. The incidence of kidney cancer in Iran: a systematic review and meta-analysis. BioMedicine. 2018 Jun;8(2).
  10. Tolou-Ghamari Z. Prevalence of kidney, renal pelvis, and ureter cancers in Isfahan province, Iran. Journal of Archives in Military Medicine. 2019 Jun 30;7(1-2).
  11. Basiri A, Shakhssalim N, Jalaly NY, Miri HH, Partovipour E, Panahi MH. Difference in the incidences of the most prevalent urologic cancers from 2003 to 2009 in Iran. Asian Pacific Journal of Cancer Prevention. 2014;15(3):1459-63.
  12. Mirzaei M, Pournamdar Z, Salehiniya H. Epidemiology and trends in incidence of kidney cancer in Iran. Asian Pacific Journal of Cancer Prevention. 2015;16(14):5859-61.
  13. Tahbaz R, Schmid M, Merseburger AS. Prevention of kidney cancer incidence and recurrence: lifestyle, medication and nutrition. Current opinion in urology. 2018 Jan 1;28(1):62-79.
  14. Cheungpasitporn W, Thongprayoon C, O’corragain OA, Edmonds PJ, Ungprasert P, Kittanamongkolchai W, Erickson SB. The risk of kidney cancer in patients with kidney stones: a systematic review and meta-analysis. QJM: An International Journal of Medicine. 2015 Mar 1;108(3):205-12.
  15. Gonzalez HC, Lamerato L, Rogers CG, Gordon SC. Chronic hepatitis C infection as a risk factor for renal cell carcinoma. Digestive diseases and sciences. 2015 Jun;60(6):1820-4.
  16. Ljungberg B, Albiges L, Abu-Ghanem Y, Bensalah K, Dabestani S, Fernández-Pello S, Giles RH, Hofmann F, Hora M, Kuczyk MA, Kuusk T. European association of urology guidelines on renal cell carcinoma: the 2019 update. European urology. 2019 May 1;75(5):799-810.
  17. DeCastro GJ, McKiernan JM. Epidemiology, clinical staging, and presentation of renal cell carcinoma. Urologic Clinics of North America. 2008 Nov 1;35(4):581-92.
  18. Kim Y, Kang G, Moon SB. Increasing utilization of abdominal CT in the Emergency Department of a secondary care center: does it produce better outcomes in caring for pediatric surgical patients?. Annals of surgical treatment and research. 2014 Nov;87(5):239.
  19. Maehara CK, Silverman SG, Lacson R, Khorasani R. Journal club: Renal masses detected at abdominal CT: radiologists' adherence to guidelines regarding management recommendations and communication of critical results. American Journal of Roentgenology. 2014 Oct;203(4):828-34.
  20. Smith-Bindman R, Miglioretti DL, Johnson E, Lee C, Feigelson HS, Flynn M, Greenlee RT, Kruger RL, Hornbrook MC, Roblin D, Solberg LI. Use of diagnostic imaging studies and associated radiation exposure for patients enrolled in large integrated health care systems, 1996-2010. Jama. 2012 Jun 13;307(22):2400-9.
  21. Falebita OA, Mancini S, Kiely E, Comber H. Rising incidence of renal cell carcinoma in Ireland. International urology and nephrology. 2009 Mar 1;41(1):7-12.
  22. King SC, Pollack LA, Li J, King JB, Master VA. Continued increase in incidence of renal cell carcinoma, especially in young patients and high grade disease: United States 2001 to 2010. The Journal of urology. 2014 Jun;191(6):1665-70.
  23. Khafaja S, Kourie HR, Matar D, Sader-Ghorra C, Kattan J. Kidney cancer in Lebanon: a specific histological distribution?. Asian Pacific Journal of Cancer Prevention. 2015;16(1):363-5.
  24. Wu J, Zhang P, Zhang G, Wang H, Gu W, Dai B, Zhang H, Shi G, Shen Y, Zhu Y, Zhu Y. Renal cell carcinoma histological subtype distribution differs by age, gender, and tumor size in coastal Chinese patients. Oncotarget. 2017 Sep 22;8(42):71797.
  25. Leibovich BC, Lohse CM, Crispen PL, Boorjian SA, Thompson RH, Blute ML, Cheville JC. Histological subtype is an independent predictor of outcome for patients with renal cell carcinoma. The Journal of urology. 2010 Apr;183(4):1309-16.
  26. Mulders PF, Brouwers AH, Hulsbergen-van Der Kaa CA, Van Lin EN, Osanto S, De Mulder PH. Guideline'Renal cell carcinoma'. Nederlands tijdschrift voor geneeskunde. 2008 Feb 1;152(7):376-80.

 

 

medical journal of mashhad university of medical sciences
Volume 63, Issue 5
January and February 2021
Pages 2655-2661

Files

Share

How to cite

Statistics