Brain / Behavioral systems in patients with obsessive-compulsive disorder, cardiovascular and normal people

Document Type : Research Paper

Authors

1 PhD Student in General Psychology, Science and Research Branch, Islamic Azad University, Tehran, Iran

2 Associate Professor, Department of Educational Psychology, Faculty of Psychology and Educational Sciences, Allameh Tabatabai University, Tehran, Iran.

3 Assistant Professor, Department of Psychology, Islamic Azad University, Science and Research Branch, Tehran, Iran

Abstract

Abstract
Introduction: Considering the importance of brain structures and functional systems in psychopathology and considering the research gap in comparing brain / behavioral systems, this study aimed to compare brain / behavioral systems in cardiovascular patients, individual’s Compulsive obsessions and ordinary people were performed.
Methods: The research method was applied in terms of purpose and 2-comparative in terms of implementation method. Data from 150 people including 50 healthy people, 50 cardiovascular patients referring to Tehran medical sciences hospitals for medical examinations in Tehran and 50 obsessive-compulsive patients referring to psychology and psychiatric clinics in Tehran in 1397 Was collected. Research samples using the method in Doss were reduced. The Gary-Wilson personality questionnaire was used as a research tool. Data were analyzed using analysis of variance and Scheffe post hoc test.
Results: Analysis of variance showed that there was a difference between the dimensions of brain / behavioral systems in cardiovascular patients, obsessive-compulsive disorder and normal people (p≥0.01). Post hoc test showed that in the components of passive avoidance, the group of heart patients was more than obsessive and in the components of active avoidance, extinction, war, escape, escape / avoidance system, the group of obsessive was more than the other group Was (p≥0.05). In the component of behavioral activation system, heart patients were more than normal people, but this difference was not significant with the group of obsessive-compulsive patients.
Conclusion: Cardiovascular disease and obsessive-compulsive disorder have a significant relationship and can be appropriate components in psychological analysis of the occurrence of these disorders.

Keywords

References

  1. Chen XF, Chen X, Tang X. Short-chain fatty acid, acylation and cardiovascular diseases. Clinical Science.
    2020 Mar;134(6):657-76.
    2. Bloom DE, Chisholm D, Jané-Llopis E, Prettner K, Stein A, Feigl A. From burden to" best buys": reducing the
    economic impact of non-communicable disease in low-and middle-income countries. Program on the Global
    Demography of Aging; 2011 Oct.
  2. 3. Khanjani, Z, Farooqi, P .; Yaghobi, AS . Psychological Risk Factors in Coronary Heart Disease: An Analysis
    of the Role of Personality and Coping Styles in Heart Disease. Medical Journal of Tabriz University of
    Medical Sciences,2010. 32 (3): 34-30.
    4. Han Y, Zeng H, Jiang H, Yang Y, Yuan Z, Cheng X, Jing Z, Liu B, Chen J, Nie S, Zhu J. CSC expert
    consensus on principles of clinical management of patients with severe emergent cardiovascular diseases
    during the COVID-19 epidemic. Circulation. 2020 May 19;141(20):e810-6.
    5. Hildon Z, Montgomery SM, Blane D, Wiggins RD, Netuveli G. Examining resilience of quality of life in the
    face of health-related and psychosocial adversity at older ages: what is “right” about the way we age?. The
    gerontologist. 2010 Feb 1;50(1):36-47.
    6. Friedman M, Rosenman RH. Association of specific overt behavior pattern with blood and cardiovascular
    findings: blood cholesterol level, blood clotting time, incidence of arcus senilis, and clinical coronary artery
    disease. Journal of the American medical association. 1959 Mar 21;169(12):1286-96.
    7. Bey K, Weinhold L, Grützmann R, Heinzel S, Kaufmann C, Klawohn J, Riesel A, Lennertz L, Schmid M,
    Ramirez A, Kathmann N. The polygenic risk for obsessive‐ compulsive disorder is associated with the
    personality trait harm avoidance. Acta Psychiatrica Scandinavica. 2020 Oct;142(4):326-36.
    8. Pittenger C, Kelmendi B, Bloch M, Krystal JH, Coric V. Clinical treatment of obsessive compulsive disorder.
    Psychiatry (Edgmont) 2005; 2(11): 34– 43.
    9. Association AP. Diagnostic and Statistical Manual of Mental Disorders, 5th Edition: DSM-5. 5 ed.
    Washington, D.C: American Psychiatric Publishing; 2013. p. 991.
    10. Costa PT, McCrae RR. Influence of extraversion and neuroticism on subjective well-being: happy and
    unhappy people. Journal of personality and social psychology. 1980 Apr;38(4):668.
    11. Larsen RJ, Ketelaar T. Personality and susceptibility to positive and negative emotional states. Journal of
    personality and social psychology. 1991 Jul;61(1):132.
    12. Gray JA. Elements of a two-process theory of learning. Academic Press; 1975.
    13. Gray, J. A., & McNaughton, N. (2000). The neuropsychology of anxiety (2nd ed.). New York: Oxford
    University Press.
    14. Broerman RL, Ross SR, Corr PJ. Throwing more light on the dark side of psychopathy: An extension of
    previous findings for the revised Reinforcement Sensitivity Theory. Personality and Individual Differences.
    2014 Oct 1;68:165-9.
    15. Jaśko K, Czernatowicz-Kukuczka A, Kossowska M, Czarna AZ. Individual differences in response to
    uncertainty and decision making: The role of behavioral inhibition system and need for closure. Motivation
    and Emotion. 2015 Aug 1;39(4):541-52.
    16. Kokkinos CM, Voulgaridou I. Links between relational aggression, parenting and personality among
    adolescents. European Journal of Developmental Psychology. 2017 May 4;14(3):249-64.
    17. Heym N, Ferguson E, Lawrence C. An evaluation of the relationship between Gray’s revised RST and
    Eysenck’s PEN: Distinguishing BIS and FFFS in Carver and White’s BIS/BAS scales. Pers Individ Diff 2008;
    45: 709-15
    18. Johnson SL, Turner RJ, Iwata N. BIS/BAS levels and psychiatric disorder: An epidemiological study. Journal
    of psychopathology and behavioral assessment. 2003 Mar 1;25(1):25-36.
    19. Dawe S, Loxton NJ. The role of impulsivity in the development of substance use and eating disorders.
    Neuroscience & Biobehavioral Reviews. 2004 May 1;28(3):343-51.
    20. Kasch KL, Rottenberg J, Arnow BA, Gotlib IH. Behavioral activation and inhibition systems and the severity
    and course of depression. Journal of abnormal psychology. 2002 Nov;111(4):589.
    21. Wells A, Davies MI. The Thought Control Questionnaire: A measure of individual differences in the control of
    unwanted thoughts. Behaviour research and therapy. 1994 Nov 1;32(8):871-8.
    22. Coles ME, Schofield CA, Pietrefesa AS. Behavioral inhibition and obsessive–compulsive disorder. Journal of
    anxiety disorders. 2006 Jan 1;20(8):1118-32.
    23. Chamberlain SR, Blackwell AD, Fineberg NA, Robbins TW, Sahakian BJ. The neuropsychology of obsessive
    compulsive disorder: the importance of failures in cognitive and behavioural inhibition as candidate
    endophenotypic markers. Neuroscience & Biobehavioral Reviews. 2005 May 1;29(3):399-419.
    24. Picó-Pérez M, Moreira PS, de Melo Ferreira V, Radua J, Mataix-Cols D, Sousa N, Soriano-Mas C, Morgado
    P. Modality-specific overlaps in brain structure and function in obsessive-compulsive disorder: Multimodal
    meta-analysis of case-control MRI studies. Neuroscience & Biobehavioral Reviews. 2020 May 1;112:83-94.
    25. Gray, J. A., & Mcnaughton, N. The psychology of Anxiety and Enquiry in to the functions of the septo
    hippocampus system, 2000. 
  3. 26. MahmoodoAlilou Majid, Beyrami Mansour, Nemati Soguli Tape Fatemeh . Relationship between Behavioral
    Activation / Inhibitory Systems and Personality Dimensions with Coronary Heart Disease. Medical journal of
    Tabriz University of Medical Sciences:2010, 32 (4): 85-80.
    27. De Gucht, V., Fischler, B., & Heiser, W. Neuroticism, alexithymia, negative affect, and positive affect as
    determinants of medically unexplained symptoms. Personality and Individual Differences, 2014. 36(7), 1655-
    1667.
    28. Wilson GD, Gray JA, Barrett PT. A factor analysis of the Gray-Wilson personality questionnaire. Personality
    and Individual Differences. 1990 Jan 1;11(10):1037-44.
    29. Azad Fallah P, Dadsetan P, Ezheyi J, Moazani M. Stress, activity, brain / behavioral apparatus, and changes in
    secretory immunoglobulin A. Journal of Psychology. 2000; 3 (9): 3-18.
    30. Corr PJ. Reinforcement sensitivity theory and personality. Neuroscience & Biobehavioral Reviews. 2004 May
    1;28(3):317-32.
    31. Hassani J. BAS, BIS and FFS in obsessivecompulsive patients. Abstracts of the 19th European Congress of
    Psychiatry 2011; 26: 959-969.
    32. Abolghasemi A, Soltani Shal R. A comparison of brain behavioral systems and emotional regulation in women
    with compulsive hoarding and other obsessive-compulsive disorders. Feyz. 2019; 23 (1) :75-82
    33. Ekman PE, Davidson RJ. The nature of emotion: Fundamental questions. Oxford University Press; 1994.
    34. Baxter LR, Schwartz JM, Bergman KS, Szuba MP, Guze BH, Mazziotta JC, Alazraki A, Selin CE, Ferng HK,
    Munford P, Phelps ME. Caudate glucose metabolic rate changes with both drug and behavior therapy for
    obsessive-compulsive disorder. Archives of general psychiatry. 1992 Sep 1;49(9):681-9.
    35. Saxena S, Rauch SL. Functional neuroimaging and the neuroanatomy of obsessive-compulsive disorder.
    Psychiatric Clinics of North America. 2000 Sep 1;23(3):563-86.
Medical Journal of Mashhad university of Medical Sciences
Volume 64, Issue 1
March and April 2021
Pages 2467-2481

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