Comparison of Interval and Continuous Training on Growth Differentiation Factor 15, Pancreatic beta cell function and insulin resistance in Women with Type 2 Diabetes

Document Type : Research Paper

Authors

1 PhD student,Department of Physical Education and Sport Sciences, Najafabad Branch, Islamic Azad University, Najafabad, Iran.

2 Assistant professor, Sport Medicine Research Center, Najafabad Branch, Islamic Azad University, Najafabad.Iran

3 Professor, Department of Exercise Physiology,faculty of sport sciences, University of Isfahan, Iran

Abstract

Introduction: Exercise increases glucose intake and is an effective way to control diabetes mellitus. The aim of this study was to investigate the effect of interval and continuous exercise on GDF-15, pancreatic beta cell function and insulin resistance in women with type 2 diabetes.
Materials and Methods: 45 women with type 2 diabetes with a mean age of 38.69±3.11 and fasting blood sugar of 9.78±1.25 mmol/l were randomly divided into three groups: continuous exercise, interval exercise and control. Continuous exercise consisted of twelve weeks, 3 sessions per week from 50 to 75% of maximum heart rate. Interval exercise continued from 75 to 90% of maximal heart rate. Sampling was performed before and after the intervention. Dependent t-test was used to compare within-group changes and analysis of covariance was used to compare between groups.
Results: According to the statistical results, in the continuous group, a significant decrease was seen in the post-test compared to the pre-test, and in the interval group, an increase in the level of GDF-15 was observed. There was a significant difference between the mean insulin resistance in the pre-test and post-test periods in the continuous and interval groups compared to the control group. In the continuous and interval groups, there was a significant difference between the mean performance of beta cells in the pre- and post-period periods compared to the control group (P= 0.05).
Conclusion: Performing a period of continuous and interval exercise is effective in improving beta cell function, blood glucose Reduction and improving insulin resistance.

Keywords


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