Echocardiographic changes of patients with hypertrophic cardiomyopathy who referred to Ghaem hospital between 2014 to 2018

Document Type : Research Paper

Authors

1 Faculty of medicine, Mashhad university of medical sciences, Mashhad, Iran.

2 Assistant Professor, Department of Cardiology, Echocardiography Fellowship, Vascular Surgery Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

3 Professor, Department of Cardiology, Echocardiography Fellowship, Vascular Surgery Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

4 Assistant Professor of Community Medicine, Clinical Research Development Unit, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran

5 Associate Professor, Department of Cardiology, Echocardiography Fellowship, Vascular Surgery Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Abstract

Introduction: Hypertrophic cardiomyopathy is the most common genetic heart disease which is described as the thickening of the heart wall and causes abnormal cardiac load. It can be associated with dangerous complications such as heart failure, atrial fibrillation, myocardial infarction and even sudden death. In this study we investigated echocardiographic findings in Hypertrophic cardiomyopathy patients.
Methods & Materials: In the present study echocardiographic records of 58 patients who were referred to echocardiography clinic of Ghaem hospital between March 2014 and March 2018 were analyzed. After investigation and categorizing the data in echocardiographic recordings, these data were analyzed using SPSS software version 22 and significance level was set as p<0.05. Exclusion criteria was included patients with suboptimal echocardiography view.
Results: the most common hypertrophy phenotype among the patients was anterolateral phenotype (44.8%). In patients with mild and severe left ventricular outlet tract obstruction, 60% of them had anterolateral phenotype. Among the patients with mitral regurgitation, in 69.6% of them the etiology was systolic anterior movement. In the present study 21.8%, 23.6% and 20% of patients had mild, moderate and severe left atrial enlargement respectively. Left atrial enlargement severity was significantly associated with the degree of diastolic dysfunction. (P<0.001)
Conclusion: As the anterolateral phenotype is the most common pattern in patients with hypertrophic cardiomyopathy and associated with more incidence of mitral regurgitation and LV out flow track obstruction, patients with this phenotype need to be evaluated more precisely.

Keywords

References

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medical journal of mashhad university of medical sciences
Volume 64, Issue 2
July and August 2021
Pages 2925-2934

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