Prevalence of Renal Artery Stenosis and Its Risk Factors in Non Diabetic Patients with Coronary Artery Disease

Document Type : Research Paper

Authors

1 Assistant professor of Cardiology, Mashhad University of Medical Sciences, Mashhad, Iran

2 Medical Student, Mashhad University of Medical Sciences, Mashhad, Iran

3 General Practitioner, Mashhad University of Medical Sciences, Mashhad, Iran

Abstract

Introduction
 
Ischemic nephropathy can cause end stage renal disease in uremic patients. Renal artery stenosis caused by atherosclerosis is a progressive disease which maybe presented by kidney dysfunction, renal failure and acute pulmonary edema. In this study we wanted to findout the prevalence of renal artery stenosis in non diabetic patients with CAD and its relation with cardiovascular risk factors for finding the necessity of concurrency of renal and coronary angiography.
Materials and Methods
In this descriptive study in 2009-2010 in Imam Reza  Hospital ,   204  non diabetic patients who had coronary stenosis with inclusion criteria :1- stenosis of more than one vessel or its equivalent(more than 50 percent ) 2-undertreatment hypertension and increased intra-arterial pressure more than 140/90mmhg3- serum creatinin over 1.5 mg/dl underwent nonselective renal angiography during coronary angiography, data analyzed with SPSS software and  K2 test, independent sample t test and logistic regression with p value less than 0.05.
Results
Among multiple variables that had meaningful relation with RAS only increased diastolic intra -arterial pressure, number of involved coronary artery and undertreatment hypertension could predict renal artery stenosis.
Conclusion
In these  3 groups of patients  such as: patients with more than one vessel stenosis (more than 50%), increased diastolic intra-arterial pressure and undertreatment hypertension, Concurrency of non selective renal artery angiography without non invasive test for assessment of  renal artery stenosis during coronary artery angiography is recommended.
 

Keywords

medical journal of mashhad university of medical sciences
Volume 55, Issue 4 - Serial Number 4
January and February 2013
Pages 242-249

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