Evaluation common Carotid Intima-Media Thickness in patients with psoriasis and comparison with control group

Document Type : Research Paper

Authors

1 Dermatology Department, Faculty of Medicine, Islamic Azad University Mashhad Branch, Assistant Professor, Mashhad, Iran.

2 Faculty of Medicine, Islamic Azad University Mashhad Branch, Medical Student, Mashhad, Iran.

3 Faculty member of nursing, Islamic Azad University Mashhad Branch, Master of Nursing Education, Mashhad, Iran.

4 Department of Emergency Medicine, Faculty of Medicine, Assistant Professor, Mashhad University of Medical Science, Mashhad, Iran.

5 Radiology Department, Faculty of Medicine, Islamic Azad University Mashhad Branch, Assistant Professor, Mashhad, Iran.

6 Faculty member of nursing, Islamic Azad University Mashhad Branch, Nursing Student, Mshhad, Iran.

Abstract

Introduction: Psoriasis is a chronic inflammation of the skin-immune system characterized by arterial erythematous plaques. Carotid artery intima measurement can be a tool for early detection of atherosclerosis in the pre-occlusion stage and has clinical signs.
Material&Method: This case-control study was performed on 30 patients with psoriasis and 30 control people aged 20 to 60 years who referred to the dermatology clinic at 22 Bahman Hospital in Mashhad during 2018-2019 , sampling was performed by available method. After explaining the research process and obtaining patients informed concept, data was recorded in the checklist.
Radiologist colleague of this study using ultrasound for a Carotid-Intima Media Thickness (CIMT) measurement. In this study of SPSS16 and statistical tests of Anova, Man Whitney, and Pearson were used to analyze the data.
Findings: CIMT was found in patients and the control group at 0.059 ± 0.51 and 0.047 ± 0.47 mm, respectively ( p value= 0.010). Pearson correlation coefficient did not report a significant relationship between mean CIMT in patients with age, sex and BMI. \
Conclusion: Since CIMT has been reported to be significantly higher in patients with psoriasis, stricter control of other risk factors for atherosclerosis than others and stricter control of inflammation in these individuals are necessary.

Keywords

References

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medical journal of mashhad university of medical sciences
Volume 64, Issue 4
November and December 2021
Pages 3440-3446

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