Prevalence of hypertension and its control in population aged 35-65 between 1386-1388 in Mashhad

Document Type : Research Paper


1 Cardiovascular Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

2 Student research committee, International UNESCO center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.

3 cardiovascular research center, faculty of medicine, Mashhad, Iran

4 cardiovascular research center, faculty of medicine, Mashhad University of Medical Sciences, Mashhad, Iran

5 Department of Epidemiology and Biostatistics, Social Determinants of Health Research center, Mashhad University of Medical Sciences, Mashhad,Iran

6 International UNESCO center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.


Introduction: Blood pressure is one of the most important risk factors for cardiovascular disease and plays an important role in the progression of stroke, myocardial infarction, heart failure and kidney failure. Therefore, the aim of this study was to investigate the prevalence of hypertension and its control in MASHAD cohort study.
Methods: This study was performed on the MASHAD cohort study. Subjects in this study were divided into three groups with normotensive, pre-hypertensive and hypertensive subjects. The significance level of the tests was considered less than 5%.
Results: In this cross-sectional study, 9704 individuals were recruited, of which 33.4% were healthy, 35% had pre-hypertension and 31.6% had hypertension. The prevalence of hypertension in men under 40 years was 15.9% and it was more than women. Also, the frequency of hypertension in women but not in men increased with age. Of all patients with hypertension in this study, 58.5% were aware of their disease. This number was 43.4% in men and 66.6% in women. Hypertension was controlled in 24% of patients, 16.3% of men and 28.6% of women.
Conclusion: The results of this study showed that more than one third of the study population had high blood pressure and more than one third had pre-hypertension. Also, more than half of the people were not aware of their blood pressure, and only 24% of those who were aware of their disease were able to control their disease.


  1. Wu Y, Huxley R, Li L, Anna V, Xie G, Yao C, et al. Prevalence, awareness, treatment, and control of
    hypertension in China: data from the China National Nutrition and Health Survey 2002. Circulation.
    2. Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo Jr JL, et al. Seventh report
    of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure.
    hypertension. 2003;42(6):1206-52.
    3. Golan DE, Tashjian AH, Armstrong EJ. Principles of pharmacology: the pathophysiologic basis
    of drug therapy: Lippincott Williams & Wilkins; 2011.
    4. Kearney PM, Whelton M, Reynolds K, Muntner P, Whelton PK, He J. Global burden of
    hypertension: analysis of worldwide data. The lancet. 2005;365(9455):217.23-
    5. Gu D, Reynolds K, Wu X, Chen J, Duan X, Muntner P, et al. Prevalence, awareness, treatment,
    and control of hypertension in China. Hypertension. 2002;40(6):920-7.
    6. Niebylski M. World Hypertension Day.
    7. Ishii M. The sixth report of the joint national committee on prevention, detection, evaluation,
    and treatment of high blood pressure, and 1999 world health organization-international society of
    hypertension guidelines for the management of hypertension. Nihon rinsho Japanese journal of clinical
    medicine. 2000;58:267-75.
    8. Ghayour-Mobarhan M, Moohebati M, Esmaily H, Ebrahimi M, Parizadeh SMR, HeidariBakavoli AR, et al. Mashhad stroke and heart atherosclerotic disorder (MASHAD) study: design,
    baseline characteristics and 10-year cardiovascular risk estimation. International journal of public health.
  2. 9. Chobanian A. National heart, lung, and blood institute; national high blood pressure education
    program coordinating committee. seventh report of the joint national committee on prevention, detection,
    evaluation, and treatment of high blood pressure. Hypertension. 2003;42:1206-52.
    . بررسی توزیع جغرافیایی موارد مسمومیت مراجعه کننده به al etشاکری, افشاری, آقاجانی, حسین, محمدی د, ابراهیم, .10
    اورژانس مسمومین بیمارستان امام رضا )ع( مشهد. مجله دانشکده پزشکی دانشگاه علوم پزشکی مشهد. 2016;59(3:)8-171.
    11. Egan BM, Zhao Y, Axon RN. US trends in prevalence, awareness, treatment, and control of
    hypertension, 1988-2008. Jama. 2010;303(20):2043-50.
    12. Esteghamati A, Abbasi M, Alikhani S, Gouya MM, Delavari A, Shishehbor MH, et al.
    Prevalence, awareness, treatment, and risk factors associated with hypertension in the Iranian population:
    the national survey of risk factors for noncommunicable diseases of Iran. American journal of
    hypertension.620-6:)6(21;2008 .
    13. van Rossum CT, van de Mheen H, Witteman JC, Hofman A, Mackenbach JP, Grobbee DE.
    Prevalence, treatment, and control of hypertension by sociodemographic factors among the Dutch
    elderly. Hypertension. 2000;35(3):814-21.
    14. Fryar CD ,Ostchega Y, Hales CM, Zhang G, Kruszon-Moran D. Hypertension prevalence and
    control among adults: United States, 2015-2016. 2017.
    15. Beunza JJ, Martínez-González MÁ, Ebrahim S, Bes-Rastrollo M, Núñez J, Martínez JA, et al.
    Sedentary behaviors and the risk of incident hypertension: the SUN Cohort. American journal of
    hypertension. 2007;20(11):1156-62.
    16. Warburton DE, Charlesworth S, Ivey A, Nettlefold L, Bredin SS. A systematic review of the
    evidence for Canada's Physical Activity Guidelines for Adults .International journal of behavioral
    nutrition and physical activity. 2010;7(1):1-220.
    17. Cornelissen VA, Smart NA. Exercise training for blood pressure: a systematic review and meta‐
    analysis. Journal of the American heart association. 2013;2(1):e004473.
    18. Whelton PK, He J, Appel LJ, Cutler JA, Havas S, Kotchen TA, et al. Primary prevention of
    hypertension: clinical and public health advisory from The National High Blood Pressure Education
    Program. Jama. 2002;288(15):1882-8.
    19. Moraes-Silva IC, Mostarda C, Moreira ED, Silva KAS, dos Santos F, De Angelis K, et al.
    Preventive role of exercise training in autonomic, hemodynamic, and metabolic parameters in rats under
    high risk of metabolic syndrome development. Journal of applied physiology. 2013;114(6.786-91:)
    20. Araujo AJSd, Santos ACVd, Souza KdS, Aires MB, Santana-Filho VJ, Fioretto ET, et al.
    Resistance training controls arterial blood pressure in rats with L-NAME-induced hypertension.
    Arquivos brasileiros de cardiologia. 2013;100:339-46.
    21. Brown MD, Feairheller DL. Are there race-dependent endothelial cell responses to exercise?
    Exercise and sport sciences reviews. 2013;41(1):44.
    22. Feairheller DL, Park J-Y, Rizzo V, Kim B, Brown MD. Racial differences in the responses to
    shear stress in human umbilical vein endothelial cells. Vascular health and risk management. 2011;7:425.
    23. Minh HV, Byass P, Huong DL, Chuc NTK, Wall S. Risk factors for chronic disease among
    rural Vietnamese adults and the association of these factors with sociodemographic variables: findings
    from the WHO STEPS survey in rural Vietnam, 2005. 2007.
    24. Le C, Chongsuvivatwong V, Geater A. Contextual socioeconomic determinants of
    cardiovascular risk factors in rural south-west China: a multilevel analysis. BMC Public Health.
    25. Lipowicz A. Hypertension among Polish males during the economic transition. Economics &
    Human Biology. 2007;5(1):61-73.
    26. Samal D, Greisenegger S, Auff E, Lang W, Lalouschek W. The relation between knowledge
    about hypertension and education in hospitalized patients with stroke in Vienna. Stroke.
    27. Morenoff JD, House JS, Hansen BB, Williams DR, Kaplan GA, Hunte HE. Understanding
    social disparities in hypertension prevalence, awareness, treatment, and control: the role of neighborhood
    context. Social science & medicine. 2007;65(9):1853-66.
    28. Pereira M, Lunet N, Azevedo A, Barros H. Differences in prevalence, awareness, treatment and
    control of hypertension between developing and developed countries. Journal of Hypertension.
    29. Wang Y, Wang QJ. The prevalence of prehypertension and hypertension among US adults
    according to the new joint national committee guidelines: new challenges of the old problem. Archives
    of internal medicine. 2004;164(19):2126-34.
    30. HAGHDOUST A, Sadeghirad B, REZAZADEH KM. Epidemiology and heterogeneity of
    hypertension in Iran: a systematic review. 2008.