Relationship between severity of acne vulgaris and androgenetic alopecia (baldness) in men

Document Type : Research Paper

Authors

1 dermatology department, Faculty of Medicine, Birjand University of Medical Sciences, Birjand , Iran.

2 Cutaneous Leishmaniasis Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

3 3. Department of Biostatistics & Epidemiology, Faculty of Health, Management & Social Determinants of Health Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

4 Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

5 Cutaneous Leishmaniasis Research Center, Mashhad University of Medical Science, Mashhad, IRAN.

Abstract

Introduction: Due to the common pathogenesis of acne and androgenetic alopecia, many studies have been performed on the association of acne with alopecia in women, but this study tries to evaluate the relationship between the severity of acne and alopecia in men.
Methods: This descriptive-correlational study was performed on 150 male patients with acne referred to the clinic of Imam Reza Hospital, Mashhad. The diagnosis of acne was made based on the clinical picture and by examining the patients, the severity of acne, the presence of alopecia in the person and its severity were evaluated. The severity of acne was divided into five degrees: mild, moderate, relatively severe, severe and very severe, depending on the type, number and location of the lesions. The severity of alopecia was divided into seven degrees according to the Hamilton-Norwood classification system. Chi-square and Mann-Whitney tests were used to analyze the data and the relationship between variables was assessed using Spearman correlation coefficient.
Findings: There is a correlation between the severity of acne and the severity of alopecia and due to the positive correlation coefficient with increasing severity of acne, the severity of alopecia also increases and this relationship is significant. (P-value=0.018 and rs=0.218)
Discussion: In our study, there was a significant relationship between the severity of acne and the severity of alopecia, so that with increasing severity of acne, the severity of alopecia increases.

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1-Zaenglein AL. Acne Vulgaris. N Engl J Med. 2018; 379(14): 1343-1352.
2-Kanwar IL, Haider T, Kumari A, Dubey S, Jain P, Soni V. Models for acne: A comprehensive study. Drug Discov Ther. 2018; 12(6): 329-340.
3-Alison M, Layton E, Anne E, Christos C. Acne. In: Griffiths C, Barker J, Blelker T, Chalmers R, Creamer D, editors. Rook’s Textbook of Dermatology.8th ed.UK:Wiley-Blackwell publishing; 2016.p.90.1-90.64
4-Uysal G, Sahin Y, Unluhizarci K, Ferahbas A, Uludag SZ, Aygen E, et al. Is acne a sign of androgen excess disorder or not?.  Eur J Obstet Gynecol Reprod Biol. 2017; 211: 21-25.
5-Marks DH, Senna MM. Androgenetic Alopecia in Gender Minority Patients. Dermatol Clin J. 2019; 38(2): 239-247.
6-Adil A, Godwin M. The effectiveness of treatments for androgenetic alopecia: A systematic review and meta-analysis. J Am Acad Dermatol. 2017; 77(1): 136-141.
7-Tanaka Y, Aso T, Ono J, Hosol R, Kaneko T. Androgenetic Alopecia Treatment in Asian Men. J Clin Aesthet Dermatol. 2018; 11(7): 32-35.
8-Ho CH,  Sood T, Zito PM. Androgenetic Alopecia. Last Update: August 10, 2020. Available from: https://www.ncbi.nlm.nih.gov/books/NBK430924
9-Andrew G, Rodney D, Paul F, David A, Disorders of Hair.In: Griffiths C, Barker J, Blelker T, Chalmers R, Creamer D, Rookʼs Textbok of Dermatology.8th ed.UK:Wiley-Blackwell publishing; 2016.p.89.1-89.75
10-Rajan A, Grotts J, Goh C. Acne development in male androgenetic alopecia. British Association of Dermatologists 2019; 44(3): 39-40