Evaluation of correlation between thyrotropin (TSH) and body mass index (BMI) in euthyroid persons

Document Type : Research Paper


1 Assistant professor of Endocrinology Research Center / school of medicine , Mashhad University of Medical Sciences, Mashhad ,Iran

2 Posrtgraduate Student of Internal Medicine / Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad , Iran

3 Assistant professor, Department of biochemistry / Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

4 Posrtgraduate Student of ophthalmology / school of medicine,Tehran University of Medical Sciences, Tehran, Iran

5 MA / Hospital of Joybar, Medical Science University of Mazandaran,Mazandaran,Iran


Introduction: The prevalence of obesity is increasing worldwide as a warning. There are some evidences that show a relationship between thyroid hormones and weight changes. The aim of this study was to determine the relationship between thyrotropin and body mass index, in euthyroid people with different weights.
Materials and Methods: This study was conducted on healthy women who were referred to the endocrine clinic. After taking a thorough history, doing a complete physical examination, checking for signs and symptoms of hypothyroidism or hyperthyroidism and measuring their height and weight, thyroid function tests were done.
Results: Overall 283 women participated  .The mean age and BMI were 35.88±12.75 years and 26.18±6.25 Kg/m2, respectively, 11% of them were underweight, 35.5% were normal and 29.3% were overweight and 24% were suffering from obesity. The mean serum TSH level was 2.29±0.07. The lowest serum TSH levels was in people with normal BMI, but there was no significant relationship between TSH serum levels in different BMI groups.There wasn’t significant relation between BMI and TSH (r=0.108, P=0.071).
Conclusion:Based on the results of this study, there was no relationship between BMI and TSH serum levels in euthyroid women.