Evaluation of the tuberculosis epidemiology in diabetic patients at clinical and health centers in mashhad

Document Type : Research Paper

Authors

1 Assistant Professor of Infectious Diseases / Department of Infectious Diseases, Faculty of Medicine, Mashhad Islamic Azad University, Mashhad, Iran

2 Medical Student / Student Research Committee, Faculty of Medicine, Mashhad Islamic Azad University, Mashhad, Iran.

3 General Practitioner / Mashhad, Iran

Abstract

Background: Tuberculosis is the most common cause of death due to bacterial diseases in the world. Uncontrolled diabetes, via weakening the immune system cause TB bacilli proliferation. Due to high prevalence of tuberculosis in our Region, this epidemiological study Was performed  to Evaluate Epidemiology of tuberculosis in patients with diabetes mellitus.


Materials and Methods: In this retrospective study by convenience sampling, medical records of 150 patients with tuberculosis, referred  to Mashhad  health centers,Within 2007 to 2012, whom simultaneously had diabetes,were assessed. The demographic data, type of TB, clinical symptoms, laboratory and radiographic findings were Collected by data  review check lists. Data were analyzed finally by descriptive statistics of frequency distribution.
Result: All patients were Iranian, with 64/65 years as  the mean age. The mean fasting blood sugarwas 93/181mg per dL. The incidence of both diseases, in women and Urban patients was higher. Overall 76% of patients had pulmonary tuberculosis (58.7% smear-positive and 17.3% smear-negative). The most common clinical symptom was persistent cough for more than two weeks. In radiographic examination,the most common image was the pulmonary  opacity (66.6%) and the upper zone was the most conflicted Region (52%).
 Conclusion: The findings implies that the Clinical, laboratory and radiological results of TB patients in our study were similar to other studies of non-diabetic TB patients. which can demonstrate the appropriate control of diabetes in these patients and no significant effects on their  tuberculosis  treatment. Nevertheless It is recommended that, the possibility of infection should be considered in patients with diabetes, and an annual review of the risk of tuberculosis should be taken into consideration.

Keywords

medical journal of mashhad university of medical sciences
Volume 57, Issue 1 - Serial Number 1
March and April 2014
Pages 422-428

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