The effect of a period of high-intensity interval resistance training with vitamin D consumption on the changes in levels of brain-derived neurotrophic factor and malondialdehyde in inactive overweight women

Document Type : Research Paper

Authors

1 Assistant Professor, Department of Physical Education and Sport Sciences, Qaemshahr Branch, Islamic Azad University, Qaemshahr, Iran

2 MA of Physical Education, Department of Physical Education and Sport Sciences, Qaemshahr Branch, Islamic Azad University, Qaemshahr, Iran

Abstract

Introduction: In the last decade, vitamin D has attracted more attention as a non-enzymatic antioxidant compound. The aim of this study was to survey of changes in BDNF and malondialdehyde (MDA) levels after a period of high intensity interval resistance training (HIIRT) and vitamin D intake in inactive overweight women women.
Materials and Methods: The subjects were first selected by the available sampling method, then they were randomly divided into four groups: control, interval exercise, vitamin D, and combined. HIIRT was performed in three sets at intensity with 80% one maximum repetition and 2.5 minutes rest between sets. Vitamin D and combined groups consumed vitamin D (50000 units) once a week. BDNF and MDA levels were measured before and after the interventions.
Results: The findings showed that the MDA levels in the interval exercise, vitamin D and combined groups decreased after 8 weeks and BDNF levels increased significantly. But the combined intervention had a stronger effect on the change of MDA and BDNF levels compared to the other two interventions (p<0.05). In addition, no significant difference was observed between the changes in the levels of interval exercise and vitamin D (P<0.05).
Conclusion: It seems that HIIRT and vitamin D consumption can exert their protective effects in overweight people with abnormal levels of vitamin D, by reducing MDA levels and up-regulation of BDNF protein. But these effects were further developed with combined intervention.

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medical journal of mashhad university of medical sciences
Volume 67, Issue 3
May and June 2024

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