Fetal outcome in fetuses with high nuchal translucency in the first trimester screening

Document Type : Research Paper

Authors

1 Assistant Professor, Department of Obstetrics and Gynecology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

2 Associate Professor, Department of Obstetrics and Gynecology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

3 Resident, Department of Obstetrics and Gynecology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

10.22038/mjms.2025.83636.4805

Abstract

Purpose: The aim of this study was to survey fetal outcomes in the setting of high nuchal translucency at routine first-trimester screening.
Method: This retrospective study conducted in a Private perinatal clinic in Isfahan from the January 2015 to the January 2023 on all pregnant women who had a singleton pregnancy and NT than 3 mm. Fetal karyotype results, perinatal outcomes, percentage of live babies with/without abnormalities, gestational age at birth, birth weight, 5-minute Apgar score were analyzed.
Results: Out of 124 cases, 85 (68.54%) cases in our study had NT diameter between 3 to 3.99 mm, 20 (16.12%) had NT between 4 to 4.99 mm, 15 (12.09%) cases had NT between 5 to 5.99 mm, and 4 (3.22%) cases had NT more than 6 mm. Our data showed significant association between NT and rates of abortion or IUFD (P-value = 0.000), cesarean rate (P-value = 0.037), preterm labor (P-value = 0.001), low birth weight (P-value = 0.001) and abnormal Apgar (P-value = 0.001). Echo test results (P-value = 0.713), genetic test results (P-value = 0.123), malformation rate (P-value = 0.231) didn’t show any significant relationship with NT diameter.
Conclusion: In our study we found significant relationship between the NT diameter and occurrence of preterm labor, low birth weight, rate of abortion or IUFD, cesarean rate, abnormal 5-minute Apgar and malformation rate.

Keywords

Main Subjects

References

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Medical Journal of Mashhad university of Medical Sciences
Volume 68, Issue 1
March and April 2025
Pages 11-18

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