The effect of carvacrol and similar compounds on diabetic lesions: (review article)

Articles in Press

Document Type : Research Paper

Authors

1 Pharmacotherapy Department, Faculty of Pharmacy, Bagyattallah University of Medical Sciences, Tehran, Iran

2 Ph.D Exercise Physiology, Faculty of Education and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran

10.22038/mjms.2025.78230.4532

Abstract

Introduction: Carvacrol and similar compounds have multi-organ and pleiotropic effects with potency to control diabetes and to date, many efforts have been made to control and regulate diabetes. Diabetes as a metabolic disorder can affect the function of different body tissues. Here, we aimed to review some of the previous trials related to the use of Carvacrol and similar compounds in diabetic diseases such as cardiomyopathy neuropathy, and nephropathy, focusing on regulatory mechanisms.

Subjects & Methods: The present study is a descriptive review study and using several databases including Google Scholar, Web of Science, Science Direct, PubMed, and Scopus, and using the titles of diabetes and the names of their types and related names for keywords of diabetes until the end of 2022.

Results: Focusing on the effects of carvacrol and the role of similar compounds that have been used in different studies, it can be said that many studies on the positive role of carvacrol in diabetic patients include different methods and outcome measures, the vast majority of capacity studies. It shows the positive side of these compounds for diabetic people. There are several proposed pathophysiological mechanisms responsible for the effects of decreased activity on the function of different tissues in diabetic patients with different lesions.

Conclusion: Based on the review of various studies in this research, it can be emphasized the essential role of carvacrol and similar compounds in diabetic lesions, should be taken into consideration.

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Medical Journal of Mashhad university of Medical Sciences

Articles in Press, Accepted Manuscript
Available Online from 23 March 2025

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