The Effect of eight weeks of HIIT training combined with Spirulina supplementation on orexinA and asprosin in inactive overweight men

Document Type : Research Paper

Authors

1 PhD Student in Exercise Physiology, ST.C., Islamic Azad University, Tehran, Iran

2 Associate Professor, Department of Exercise Physiology, ST.C., Islamic Azad University, Tehran, Iran

3 Assistant Professor, Department of Exercise Physiology, Parand Branch, Islamic Azad University, Tehran, Iran

4 Associate Professor, Department of Exercise Physiology, South Tehran Branch, Islamic Azad University, Tehran, Iran

10.22038/mjms.2025.27012

Abstract

Introduction: Obesity and overweight are disorders with increasing prevalence and are recognized as one of the major health problems worldwide due to their high mortality. Overweight is the result of a complex interaction between environmental factors, genetic factors, and behavior, which is closely associated with metabolic syndrome, insulin resistance, and type 2 diabetes.
Methods: In the present study, 40 inactive and overweight men voluntarily and readily participated in the present study. In this study, the subjects were randomly divided into four groups: HIIT training group (10 people), Spirulina supplement group (10 people), HIIT training and Spirulina supplement group (10 people), and control group (10 people). The training groups performed the exercises for eight weeks, three sessions per week, according to the desired protocol. Spirulina supplement was taken as one 500 mg capsule daily after breakfast. To compare the data, analysis of covariance and Tukey's post hoc test were used at a confidence level of 95% using SPSS27 software.
Results: The present study showed that HIIT training combined with Spirulina supplementation, as well as the HIIT training group alone, caused significant changes in the increase in orexin A and the decrease in asprosin in inactive overweight men compared to other groups (p<0.05). It was also shown that the Spirulina supplementation group caused non-significant changes in each of the indices compared to the control group. (p<0.05)
Conclusion: Overall, the research findings show that HIIT training combined with Spirulina supplementation, as well as the training group alone, led to improvements in metabolic indices, and these changes were greater in the training group combined with the supplement compared to the other groups.

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