Effect of Fluid Therapy (IVtherapy) on Symptoms and Signs of Acute Appendicitis

Document Type : Research Paper


1 Assistant professor of Pediatric surgery, Medical University of Islamic Azad University of Mashhad, Mashhad,

2 Associate professor of Pediatric, Medical University of Islamic Azad University of Mashhad, Mashhad,

3 Assistant professor of General Sergeon, Medical University of Islamic Azad University of Mashhad, Mashhad,

4 General Physician, Mashhad,

5 MSc in Medical Biostatistic, Islamic Azad University of Mashhad, Mashhad,


In cases of acute Appendicitis with vague symptoms, the diagnosis maybe delayed and during this interval, most patients receive fluid therapy. Az a result the patients' symptoms declines and even sometimes they refuse to operate.The purpose of this study was evaluation of effect of fluid therapy on symptoms and signs of acute appendicitis.
Materials and Methods
In a prospective comparative clinical trial study 130 patients were studied.
 Patients in two groups of 65 people who qualified were studied In one group 6 hours before the surgery fluid therapy had been done and in the other group no medications or fluids were prescribed and information recorded.  Finally 6 hours after the admission, patients were operated and pathological records collected. Data classified and analyzed by SPSS software and P value of more than 0.05 considered valuable.
Based on our data, the abdominal pain, the most important sign of appendicitis, decreased meaningfully in the fluid therapy group in comparison with non rehydrated group.(p= 0.0001).  The anorexia changes (improving appetite),  reducing the tenderness and rebound tenderness were obviously different in two groups (p>0.05).
These results mean that fluid therapy has effect on signs and symptoms of appendicitis. This may result in delay or misdiagnosis of appendicitis. Thus the physician should be aware, especially in patients that have received fluid therapy. Although, we could not find any physiopathologic reason for this effect


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