Valuation of Oxidative Stress and Total Antioxidant Capacity in Women with General and Abdominal Adiposity

Document Type : Research Paper


1 MSc in Nutrition, Zabol University of medical sciences, Zabol,

2 professor of Nutrition, Tehran University of medical sciences, Tehran,

3 MSc in Biostatistic, Zabol University of medical sciences, Zabol,


 previous studies have shown that general and abdominal adiposity are closely associated with risk of diabetes and cardiovascular disease events. We sought to evaluate the oxidative stress and plasma total antioxidant capacity (TAC) levels in women with general and abdominal adiposity.
Materials and Methods
 In this study case-control, 160 women 20-45 years old were randomly selected. General information data were gathered from each sample using questionnaires and face-to-face interviews. Venous blood samples were drawn from subjects and plasma was separated. In this study, Oxidative stress levels were assessed by measuring the concentrations of plasma malondialdehyde (MDA). We also evaluated total antioxidant capacity (TAC) of plasma in subjects. 
Mean plasma concentration of MDA was significantly higher in overweight and obese women groups compared to healthy women group (pConclusion
Our results provided further evidence suggesting that obesity and, especially, abdominal adiposity was associated with elevated oxidative stress and decreased levels of TAC in plasma which in turn, may contribute to obesity related diseases such as atherosclerosis, diabetes mellitus and arterial hypertension


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