A Case Report of Cryptococcal Meningitis

Document Type : Research Paper

Authors

1 Assistant Professor of Pediatrics, Mashhad University of Medical Sciences, Mashhad,

2 - Resident of Pediatrics, Mashhad University of Medical Sciences, Mashhad,

3 Professor of Pediatrics, Shiraz University of Medical Sciences, Shiraz,

Abstract

Introduction
 
Fungi are rare causes of meningitis. Cryptococcus neoformans is the most common cause of fungal meningitis. Although meningitis is the most common form of cryptococcal disease but cryptococcal infection almost always originates from lung.
Case report
We present a 13 –year- old boy with sarcoidosis that developed fever, headache and vomiting He was hospitalized and treated with clinical diagnosis of acute bacterial meningitis, However, the treatment was not effevtive and due to hydrocephalus in brain CT, anti-TB therapy was initiated. Finally both CSF the culture and smear tested positive for cryptococcus neoformans, and the patient was successfully treated by Amphotricin and then fluconazol in a period of one year.
Conclusion: In differential diagnosis of aseptic meningitis and hydrocephalus, Cryptococcus neoformans must be considered in adition to TB meningitis.

Keywords

References

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Medical Journal of Mashhad university of Medical Sciences
Volume 55, Issue 3 - Serial Number 3
March and April 2012
Pages 190-194

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