تأثیر مصرف کلسیم ، ویتامین D و ورزش ترکیبی بر هورمون پاراتیروئید و آنزیم آلکالن فسفاتاز زنان یائسه

نوع مقاله : مقاله پژوهشی

نویسندگان

1 دکترای فیزیولوزی ورزش، دانشگاه تربیت معلم تهران، تهران، ایران

2 استادیارگروه غدد، دانشکده پزشکی دانشگاه علوم پزشکی کرمان، کرمان، ایران

3 - استادیار گروه تربیت بدنی ، دانشکده تربیت بدنی دانشگاه تربیت معلم تهران، تهران، ایران

چکیده

مقدمه
 نقش فشار مکانیکی (ورزش) بر استخوان در اثر تمرینهای بدنی در متابولیسم کلسیم و فسفر اولین بار توسط ردهال (1999) بررسی گردید. در این راستا محققین به بررسی تاثیر ورزش های مختلف بر تراکم استخوان و نشانه های آن پرداختند .
 روش کار
این مطالعه کارآزمایی بالینی در نیمه اول سال 1388 در دانشگاه علوم پزشکی کرمان انجام شده است. 30 زن یائسه سالم با میانگین سنی 54/85 سال و وزن 68/35 کیلوگرم که به طور تصادفی از بین کارمندان بازنشسته شهر کرمان انتخاب شده بودند و دامنه سنیشان بین60-48 سال بود در این تحقیق شرکت کردند و به سه گروه مساوی تقسیم شدند . گروه اول ورزش ترکیبی، گروه دوم ورزش ترکیبی به همراه مصرف کلسیم (1500 mg ) و ویتامین D (600IU ) انجام دادند و گروه سوم کلسیم ( 1500 mg) و ویتامین 600 IU ) D) مصرف نمودند. سنجش سطح کلسیم، ویتامین D، هورمون پاراتیروئید و آنزیم آلکالن فسفاتاز توسط انداز ه گیری خون با روش سینتتیک آنزیمی انجام شد. پس از اعمال متغیر مستقل مجدداً اندازهگیریهای اولیه تکرار شد. از آزمون کلموگروف – اسمیرنف و تحلیل واریانس یک طرفه و آزمون تعقیبی برای بررسی ارتباط متغیرها استفاده شد .
نتایج
 هورمون پاراتیروئید و آنزیم آلکالن فسفاتاز به ترتیب در گروه ورزش-دارو ، دارو و ورزش به طور معنی داری بالاتر بود . 
نتیجه گیری تمرین ترکیبی موجب افزایش بازسازی استخوان شد و آنزیم آلکالن فسفاتاز زنان یائسه را افزایش داد 

کلیدواژه‌ها

عنوان مقاله [English]

The Effect of Calcium and Vitamin D Consumption and Combined Training on Parathyroid Hormone and Alkaline Phosphatase of Postmenopausal Women

نویسندگان [English]

  • Hakimeh Hassanzadeh 1
  • Mohammadhosein Gozashti 2
  • Mohammadreza Dehkhoda 3
  • Ali Kazemi 3
1 PH.D in Physical Education, Tehran Tarbiat Moallem University, Tehran, Iran
2 Assistant Professor of Endocrinology, Kerman University of Medical Sciences, Kerman, Iran
3 Assistant Professor of Physical Education, Tehran Tarbiat MoallemUniversity, Tehran, Iran
چکیده [English]

Introduction
The role of mechanical stress (sport) on bone under the effect of physical exercise in calcium and phosphorus metabolism was investigated first by RedHall (1999) 23. In this regard, the researches investigated the effect of various exercise on bone density and its markers.
Materials and Methods
Thirty healthy postmenopausal women with mean age 54.85 years and 68.35 kg weight has been randomly selected from among retired employees in kerman city. Their age range was 48-60 years were participating in this research and were divided into three groups. The first group included combined sport, the second group combined sport with calcium (1500 mg) and vitamin D (1600 IU) intake and the third group were taking calcium (1500 mg) and vitamin D (1600 IU). The combined sport included some physical practices such as weight exercises, aerobic exercises, jump and agility exercises and they practice in 6 month, 3 sessions a week, and at least for 60 minutes.Evaluating the level of calcium, vitamin D, parathyroid hormone and alkalin phosphatase enzyme was done by blood test with enzyme synthetic method. After applying independent variable, the primary measurement was repeated again. With the test of kelmogrove-smirnov the analysis of one-way variance and post hoc test was used for checking the variables relationship.
Results
The amount of calcium, vitamin D, parathyroid hormone and alkaline phosphatase enzyme to arrange in sport – drug, drug and sport groups was significantly higher.
Conclusion
The combined sport (excersice) caused an increase in bone reconstruction and increased alkaline phosphatase enzyme in post menopausal women. Increasing the process of involved enzymes in bone building, prevents delay of osteoprosis, and leads to improvement in nervo-muscular function.

کلیدواژه‌ها [English]

  • Alkaline phosphates
  • Combined training
  • Calcium
  • PTH hormone
  • Postmenopausal
  • Vitamin D

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مجله دانشکده پزشکی دانشگاه علوم پزشکی مشهد
دوره 55، شماره 2 - شماره پیاپی 2
خرداد و تیر 1391
صفحه 96-101

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