The Effect of Calcium and Vitamin D Consumption and Combined Training on Parathyroid Hormone and Alkaline Phosphatase of Postmenopausal Women

Document Type : Research Paper

Authors

1 PH.D in Physical Education, Tehran Tarbiat Moallem University, Tehran, Iran

2 Assistant Professor of Endocrinology, Kerman University of Medical Sciences, Kerman, Iran

3 Assistant Professor of Physical Education, Tehran Tarbiat MoallemUniversity, Tehran, Iran

Abstract

Introduction
The role of mechanical stress (sport) on bone under the effect of physical exercise in calcium and phosphorus metabolism was investigated first by RedHall (1999) 23. In this regard, the researches investigated the effect of various exercise on bone density and its markers.
Materials and Methods
Thirty healthy postmenopausal women with mean age 54.85 years and 68.35 kg weight has been randomly selected from among retired employees in kerman city. Their age range was 48-60 years were participating in this research and were divided into three groups. The first group included combined sport, the second group combined sport with calcium (1500 mg) and vitamin D (1600 IU) intake and the third group were taking calcium (1500 mg) and vitamin D (1600 IU). The combined sport included some physical practices such as weight exercises, aerobic exercises, jump and agility exercises and they practice in 6 month, 3 sessions a week, and at least for 60 minutes.Evaluating the level of calcium, vitamin D, parathyroid hormone and alkalin phosphatase enzyme was done by blood test with enzyme synthetic method. After applying independent variable, the primary measurement was repeated again. With the test of kelmogrove-smirnov the analysis of one-way variance and post hoc test was used for checking the variables relationship.
Results
The amount of calcium, vitamin D, parathyroid hormone and alkaline phosphatase enzyme to arrange in sport – drug, drug and sport groups was significantly higher.
Conclusion
The combined sport (excersice) caused an increase in bone reconstruction and increased alkaline phosphatase enzyme in post menopausal women. Increasing the process of involved enzymes in bone building, prevents delay of osteoprosis, and leads to improvement in nervo-muscular function.

Keywords


1. Javadi A. Relation between scale calcium and vitamin D with scale bone mineral density and osteoporosis .Medical college
of Tehran university .Research center of glands.2009.
2. Gaiini A, Rajabi H. Physical Education. Tehran: Samt; 2008.
3. Motab saei N. The effect of intence aerobic exercises for 9 weeks on Parathyroid and marker of bone formation in
young women, A thesis of M.A.degree of Oromieh university.2008.
4. Aliye T, Nesnin B. Acute effect of a signal session of aerobic exercise with or without weight-lifting on bone turnover in
healty young women. Mode Rheumato 2010; 76:300-309.
5. Barhm H. Bone Mentabolism during exercise and recovery the influence of plasma volume and physical fitness. Calcif
Tissue Int 1977; 61:192-198.
6. Brent G, Seely W.Relation between the concentration and rate of change of calcium and serum intact parathyroid hormone
level s in normal humans. J clin Endocrinal Metab 1988; 67:944-950.
7. Brighton G, Katz S. Prevention and treatment of sciatic denervation disuse osteoporosis in the rat tibia with capacity
coupled electrical stimulation bone. 1985; 6:37-97.
8. Bell N, Godsen DP. The effects of muscle building exercise on vitamin D and mineral metabolism. J Bone Miner Res
1988; 3:369-373.
9. Bravo G, Gauthier P. Impact of a 12-month exercise program on the physical and phychological health of osteopenic
women. J Am Geroatr Soc 2008; 44:7,756-762.
10. Hyanfas P, Kang J. Effect of combined training on bone, body balance and gait ability: a randomized controlled study in
community dwelling elderly women. J Bone Mineral Density 2009; 26:254-259.
11. Katja A, Satu M. Effects of different training protocol on Ca+2 handing and oxidative capacity in skeletal muscle of
Atlantic Salmon. J Exp Biol 2009; 2977:78.
12. Ljunghall S, Joborn L. Reginal and systemic effects on short – term intense muscular work on plasma concentration and
content of total and ionized calcium. Eur J Clin Invest 1985; 15:248-252.
13. Lopez I, Tejero A. Direct effect of acute metabolic and respiratory acidosis on parathyroid hormone secretion in the dog. J
Bon Miner Res 2002; 17:1691-1700.
14. Linda L, Sandy S. Effects of strength and endurance exercise on calcium – regulating hormone between different levels of
physical activity. J Mech Med Biol 2005; 5:267-275.
15. Jay K. Effects of physical activity on calciotropic hormones and calcium balance in rates. J Endocrinol 2007; 119:133-742.
16. Menkens A, Mazel S. Strength training increases regional bone minral density and bone remodeling in middle-age and
older men. J Appl Physiol 2008; 74:247-278.
17. Nichols J, Nelson K. Bone minral density responses to high-intensity strength training in active older women. J Aging
Phys Act 2009; 3:26-28.
18. Optimal drop heightly for polymeric training ergonomic. 1994; 37:147-148.
19. Original research communication calcium supplementation and bone minral density in females from children to young
adulthood: a randomized controlled trail American. J Clin Nutr 2010;81:175, 880.
20. Parfill A. Vitamin D and bone health in the elderly. Am J Clin Nutr 1982; 30: 1014-1037.
21. Peterson S, Peterson M. Muscular strength and bone density with weight training in middle-aged women. Med Sci Sport
Exerc 2009; 23:499-504.
22. Palamas S, Hinton R. Weight-bearing aerobic term weight loss in overweight and obese men and women. 2009; 55:7676-
7678.
23. Redhal W, Riggs H. Research directions in osteoporosis. Am J Med 1999; 84: 275-282.
24. Rudberg A, larsson H. Serum ISO forms of bone Alkalin Phosphates increase during physical exercise in women. Calcif
Tissue Int 2000; 66:342-377.
25. Rigges B, Nelson K. Effect of long term treatment with calcitriol on calcium obsorption and mineral metabolism in
postmen pausal osteoporosis. J Clin Endocrinol Metabol 1985; 67:455.
26. Ryan A, Treuth M. Resistive training mainting bone minral density in postmenopausal women. J Calcif Tissue Int 2008;
62:205-299.
27. Stein GS, Lian J. Molecular mechanisms mediating proliferation differentiation interrelation ship during progressive
development of the osteoblast phenotype. Endocr Rev 1993; 14:424-442.
28. Smith K, Weaker I. Effect of agine on vitamin D in sufficiency in and a dult normal population int ? 2007; 7:43-440.
29. Thorsen A, Korpelanies S. Intensity of exercise int ? 2006; 17:453-455.
30. Kemmler W, Engelke K. Exercise effects of fithness and bone mineral density in early postmenopausal women: 1- year
epos results. J Med Sci Sports Exerc 2008; 34: 2475-2783.
31. Vora M, Kukre I. Effect of exercise on serum calcium and parathyroid hormone. J Clin Endocrinol Metabol 2010;
57:1067-1069.
32. William R. Text book hormones and Bahavior. Metabolism 2011; 43:67-82.