Accordance of Mammographic, Sonographic & Histopathologic Findings in Under 50 years old women with Breast Cancer Cancer Research Center - Mashhad University of Medical Sciences


1 Associated professor of Radiology, Mashhad University of Medical Sciences, Mashhad, Iran

2 Associated professor of Radiation Oncology,Mashhad University of Medical Sciences, Mashhad, Iran

3 Assistant of Radiology,Mashhad University of Medical Sciences, Mashhad, Iran

4 Associated professor of Epidemiology,Mashhad University of Medical Sciences, Mashhad, Iran


Breast cancer is the most common cancer and second cause of death due to cancer in women. According to middle age affection (40-49 years old) and advanced cases in Iranian women, early diagnosis and detection of exact tumor size is very important to select the plan of treatment.
Materials and Methods
In this survey, files of 370 breast cancer patients from 2007 to 2010 were studied. Only 60 patients with sufficient information were selected. Questionnaires based on patient mammography, ultrasound and pathology findings were completed. SPSS Software was used for statistical analysis.
The mean age of patients in this survey was 40 ±1/60 years old. Overall 16% of patients had normal mammography, 70% of them were in stage III & IV to ACR-Density classification (American College of Radiology). Mean area on lesion in mammography finding was 1042.96±1 031 mm2, sonogarphy 541.772±498 mm2 and pathology 1493.75±1617 mm2. Significant correlation (Pvalue=0/02) was seen between mammographic and metastasis tumor size. Significant correlation (Pvalue<0/001, r=0/62) was seen between mammographic and histopathologic tumor size.
Sonography is a more reliable diagnostic method in detection of lesions in patients who have high density (Stage III& IV) in mammography. Although, the average area of the lesion in mammography and ultrasound was less than pathology, it is more accurate compared to ultrasound mammography in determining tumor size before surgery. A broader study with more sample size compared to newer diagnostic techniques like MRI is recommended in determining the exact size of the tumor before surgery.


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