Prevalence of low Mineral Bone Density in Renal Transplant Recipients one Year or More after Transplantation

Authors

1 Assistant professor of Nephrology, Mashhad University of Medical Sciences, Mashhad, Iran

2 Associate Professor of Internal Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

3 PhD of Biological statistics, Mashhad, Iran

4 General Practitioner, Mashhad, Iran

5 Bachelor of government and Public management, Mashhad, Iran

6 Head nurse, Mashhad, Iran

Abstract

Introduction
Reduction in mineral bone density is a common complication following kidney transplantation and its adverse outcome could be minimized with well recognition and treatment. In this study we evaluated the prevalence of mineral bone density decrease in kidney recipients at least one year after the transplantation.
Materials and Methods
Kidney recipients from whom transplant surgery at least a year had passed and had a good kidney function were selected. Mineral bone densitometry using X- ray energy absorptiometry was performed. The serum levels of Ca, P, Alkaline Phosphatase and Paratormone were measured and the collected data were statistically analyzed.
Results
Overall 182 patients were studied. The total rate of mineral bone density decrease was 87.4%. Osteopenia in the femoral bone was 73.6% and osteoporosis was 13.8%. In the lumbar vertebrae an osteopenia of 66.5% and an osteoporosis of 20.9% were noticed. Variance of analysis showed that there were no statistically significant differences between duration of dialysis before kidney transplantation (P=0.777, P=0.420), duration of kidney transplantation (P=0.927, P=0.271), the mean of serum PTH (P=0.908, P=0.146) and calcium (P=0.348, P=0.265) in respect to densitometry of femoral bone and lumbar vertebrae.
Conclusion
The frequency of mineral bone density reduction one year after kidney transplant in patients with a good transplanted kidney function was high.

Keywords

References

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medical journal of mashhad university of medical sciences
Volume 54, Issue 4 - Serial Number 4
November and December 2012
Pages 207-211

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