Evaluation of Dobutamin Stress Echocardiography Complications in 500 Patients Referred to Ghaem Hospital

Document Type : Research Paper

Authors

1 Associated professor of Cardiology,Mashhad University of Medical Sciences, Mashhad. Iran

2 Rezident ofCardiology,Mashhad University of Medical Sciences, Mashhad. Iran

3 Medical Student, Mashhad University of Medical Sciences, Mashhad. Iran

Abstract

Introduction
Coronary artery disease is the first etiology of mortality in
Western countries and it was predicted,that up to the year 2010 it would be the main cause of human morbidity. With Respect to the increasing frequency of coronary artery disease, proper diagnosis, treatment and prevention of complications have a great importance. Many patients with chest pain could not perform diagnostic ETT, so in this group dobutamin stress echocardiography was a suitable low cost, safe, accessible & exercise independent modality of stress. Regarding the recent usage of dobutamine stress echocardiography in our country & especially in khorasan province,the aim of this descriptive study was to present 500 patients whom referred to Ghaem hospital echocardiography laboratory for ischemic diagnosis or viability assessment or both.
Materials and Methods
This study consisted of 500 patients, 273 males (54.6%) ,and 227 Females (45.4%0), 20-80 years old and also were symptomatic for ischemia. These cases were referred to Ghaem echo lab for ischemia/ viability detection between 1385-1386.
Results
Our study Patients had: systemic hypertension (46.8%), hypercholesterolemia (39.8%), diabetes (29.5%), smoking (12.6%), previous MI (11.1%) positive family history 8% CRF (8%) and obesity (5%). Among patients 345 (69%)were referred for ischemia detection, 132 (26.4%) referred for viability assessment , 23 (4.6%) for both of them, the left ventricular systolic function was normal in 168 (26.8%), mildly abnormal in 25.3%, moderate dysfunction in 12.8%, severe dysfunction in 128 patients with complication consideration, 402 patients (80.5%) had no complication and in the other patients (19.5%) test complication were occurred as arhythmia, PVC, palpitation, vomiting, nausea, rigor and the other mild complications.
Conclusion
Dobutamine stress echocardiography is an exercise independent stress modality with good safety and low level of complications.

Keywords

References

1- Geleijnse ML, Fioretti PM, Roelandt JR. Methodology, feasibility, safety and diagnostic accuracy of dobutamine
stress echocardiography. J Am Coll Cardiol 1997; 30:595-606.
2- Marwick TH. Imaging techniques of stress echocardiography. Heart 2003; 89:113-118.
3- Poldermans D, Fioretti PM, Boersma E, Cornel JH, Borst F, Vermeulen EG, et al. Dobutamineatropine stress
echocardiography and clinical data for predicting late cardiac event s in patients with suspected coronary artery disease.
Am J Med 1994; 97:119–25.
4- Poldermans D, Fioretti PM, Boersma E, Bax JJ, Thomson IR, Roelandt JR, et al. Long-term prognostic value of
dobutamine-atropine stress echocardiography in 1737 patients with known or suspected coronary artery disease: A
single-center experience. Circulation 1999; 99:757-762.
5- Trippi JA, Lee KS, Kopp G, Nelson DR, Yee KG, Cordell WH. Dobutamine stress tele-echocardiography for
evaluation of emergency department patients with chest pain. J Am Coll Cardiol 1997; 30:627–632.
6- Hung MJ, Wang CH, Cherng WJ.Can Dobutamine Stress Echocardiography Predict Cardiac Events in
Nonrevascularized Diabetic Patients Following Acute Myocardial infarction. DOI 10.1378/chest.116.5.1224
Chest 1999; 116:1224-1232.
7- Abreu JS, Di genes TC, Farias AG, Morais JM, Paes Junior JN. Safety and feasibility of dobutamine-atropine stress
echocardiography in octogenarian patients. Arq Bras Cardiol 2005; 85:198-204.
8- Sawada SG, Segar DS, Ryan, T, Brown SE, Dohan AM, Williams R,et al. Echocardiographic detection of coronary
artery disease during dobutamine infusion. Circulation 1991; 83; 1605-1614.
9- Marwick TH, D'Hondt AM, Mairesse GH, Baudhuin T. Comparative ability of dobutamine and exercise stress in
inducing myocardial ischaemia in active patients. Br Heart J 1994; 72:31-38.
10- Pingitore A, Picano E, Colosso MQ, Reisenhofer B.The Atropine Factor in Pharmacologic Stress
Echocardiography. J Am Coil Cardiol 1996; 27:1164-1170.
11-Picano E, Mathias WJr, Pingitore A, Bigi R. Safety and tolerability of dobutamine-atropine stress echocardiography:
a prospective, multicentre study. Echo Dobutamine International Cooperative Study Group. Lancet 1994; 344:1190-
1192.
12- Zahn R, Lotter R, Nohl H, Schiele R, Bergmeier C, Zander M, et al.Feasibility and safety of dobutamine stress
echocardiography: experiences with 1,000 studies. Z Kardiol 1996; 85:28-34.
13- Mertes H, Sawada SG, Ryan T, Segar DS, Kovacs R,Foltz J, et al. Symptoms, adverse effects, and complications
associated with dobutamine stressechocardiography. Experience in 1118 patients. Circulation 1993; 88;15-19.
14- Minardi G, Manzara C, Pulignano G, Pino PG, Pavaci H, Sordi M.
 Feasibility, safety and tolerability of accelerated dobutamine stressechocardiography. Cardiovascular Ultrasound
2007; 5:40. 
medical journal of mashhad university of medical sciences
Volume 54, Issue 1 - Serial Number 1
March and April 2010
Pages 25-30

Files

Share

How to cite

Statistics