Brain Venous Thrombosis

Document Type : Research Paper


1 Associate Professor of Neurology, Mashhad University of Medical sciences, Mashhad, Iran

2 Neurologist, Mashhad University of Medical sciences, Mashhad, Iran

3 Assistant Professor of Neurology, Mashhad University of Medical sciences, Mashhad, Iran

4 Assistant of Neurology, Mashhad University of Medical sciences, Mashhad, Iran


The First Cerebral vein thrombosis was reported in 1825. Early diagnosis is very important, because early treatment can prevent mortality in most eases. Also, cerebral vein thrombosis is preventable by finding the underlying etiology. True incidence of cerebral vein thrombosis is not predicative.
Materials and Methods
This descriptive study was performed from 2005 through 2006 on patients referred to Qaem Hospital neurological emergency ward. All of the patients with clinical feature of ICP rising were evaluated and underwent CT scan and MRI of brain. In cases suspicious to cerebral vein thrombosis, the disease was actually diagnosed with MR venography of brain, after discharge Patients were followed up every week for 3 weeks in neurological clinic of Qaem Hospital.
From 20 evaluated patients, 70% were female and 30% were male, in which the ratio of F/M was 3/2. Patients mean age was 30 year. The most clinical feature was headache. Underlying etiologies in above patients were: OCP consumption, post partum period, media otitis, nephrotic syndrome and Crystal abuse. In MRI and MRV assays of studied patients, 20% had superior sagital sinus, 10% lateral sinus, 5% sigmoid sinus and 65% had superior sagital and lateral sinus involvement simultaneously.
In patients who refer having headache and papilla edema, cerebral vein thrombosis should be considered. Early diagnosis is achieved by precise diagnostic methods like MRI and MRV, and the prevention of severe irreversible and fatal side effects of disease with the early treatment.


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