Evaluation of Body Mass Index & Albumin in Pts with COPD

Document Type : Research Paper

Authors

1 Associate professor of Internal Medicine, Department of Internal Medicine, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran

2 Professor of Internal Medicine, Department of Internal Medicine, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran

3 Assistant professor of Internal Medicine, Department of Internal Medicine, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran

4 Associate professor of Sotial Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

5 General practitioner

6 Resident of Sub-Specialty of Pulmonary diseases

Abstract

Introduction
Chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation and progressive development of airflow limitation. Recently besides the typical pulmonary pathology of COPD, several effects occuring outside the lungs, for example weight loss and malnutrition have been described the so called systemic effects of COPD. In this study we evaluated body mass index (BMI), serum albumin and their relationship with pulmonary function.
Materials and Methods
This descriptive study performed on 42 patients, referring to Ghaem Hospital Mashhad University of Medical Sciences, Mashhad, Iran at 2005, with the mean age of 62.82±10.54 years and the mean forced expiratory volume in the first second (FEV1) (1.38±0.76 lit.).This study was approved by the local ethics. Severity of disease was defined by global initiative for chronic lung disease (GOLD) guideline. BMI and serum albumin were measured.
Results
BMI was lower than normal in 9.5% of patients. There was a significant negative correlation between the severity of disease and BMI (p= 0.004, r= - 0.43). Furthermore the correlation between the severity of disease and serum albumin was significantly negative (p= 0.02, r= - 0.35).
Conclusion
The results of this study indicate that BMI and serum albumin decreased as the severity of disease increased. Therefore, the nutritional status is closely linked to the severity of COPD.

Keywords

References

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medical journal of mashhad university of medical sciences
Volume 51, Issue 3 - Serial Number 3
September and October 2007
Pages 155-158

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