A Study of Unilateral Proptosis and Etiology in Neurosurgery Department of Ghaem Hospital, 1995 - 2005

Document Type : Research Paper




ntroduction:Exophthalmia is defined as an abnormal protrusion of the eyeball; also labeled as proptosis. Proptosis, due to any cause, can compromise visual function and the integrity of the eye structure. The aim of this study was to evaluate etiological factors, clinical findings, imaging studies, histopathological, and prognostication in patients with exophthalmia.
Material and Methods: This descriptive study was done from 1995 to 2005 in Neurosurgery Department of Gham Hospital of Mashhad. 50 cases with documented medical history, clinical examination, and pathology reports were studied. Data was gathered in a questionnaire and analyzed with descriptive statistics and chiary-square test.
Results: There were 28 male (56%) and 22 female (44%) patients. Mean age was 32.9 years (with range of 10 months to 70 years); Mean age of female patients was 36.8 years and in male ones it was 27.8 years. Right eye was involved in 48% of patients and left eye in 52%. The most common cause of proptosis was meningioma with orbital involvement (12%), in 10% of cases it was located in the lesser wing of sphenoid and in 2% in the optic nerve sheath. Other common causes of proptosis were frontal bone osteoma with extension to orbit (8%), fibrous dysplasia (8%), orbital pseudo tumor (6%), sinus mucocele (6%), orbital cavernous hemangioma (6%), dermoid and epidermoid cysts of the orbit (6%), hydatid cyst (6%), carotid– cavernous Fistula (6%), and optic never glioma (4%). In 25%, proptosis was associated with decreased vision.
Conclusion: The most common cause of proptosis in neurosurgery ward was meningioma; mostly lesser wing sphenoid meningioma, which in most cases was associated with decreased vision.


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