Comparison of Incidence of Succinylcholine-Induced Fasciculation and Postoperative Myalgias

Document Type : Research Paper




ntroduction: Fasciculation and myalgia are common complications of succinylcholine and decrease of incidence and intensity of them will reduce succinylcholine-induced side effects. This study was done to evaluate the severity and prevalence of fasciculation and myalgia after succinylcholine and perform a comparison between three groups.
Material and Methods:In this case – control study in 2006, 75 patients with ASA I and orthopedic surgery were evaluated in Imam Reza hospital. The patients divided randomly in to three same groups. In first group thiopental and succinylcholine 1.5 mg/kg was injected, in second group propofol 2 mg/kg and succinlycholine 1.5 mg/kg and in third group thiopental and succinylcholine 3 mg/ kg was administered. Fasciculation, intubation quality after 1 min, and myalgia after 24 h were analyzed. Demografic parameters, pain scales and fasciculation data were gathered in a questionnaire and analyzed by SPSS, descriptive statistics and frequency distribution tables.
Results: Fasciculation rate was %76 in first group, 80% in second group, and %84 in third groups. Myalgia was %24 in first group , %28 in second group, and %20 in third group . There were no significant differences between group 1&2 and also 1&3 with respect to fasciculation, Intubation, and post–operative myalgia.
Conclusion:We concluded that propofol aggregates muscular relaxation versus thiopental, and low-dose versus high–dose of succinylcholine and chang to phase II block had no differences regarding to these complications.


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