Comparison of Left Ventricular Ejection Fraction and Ventricular Volume in Echocardiography and Nuclear Myocardial Perfusion Scan

Document Type : Research Paper




ntroduction: Radionuclide scanning of the heart has incremental value in diagnosis and risk stratification of coronary artery disease. Gated myocardial perfusion SPECT is a new method and the state of the art in coronary artery disease detection. This study was done to evaluate estimation of LV volume, wall motion diameters and ejection fraction by gated myocardial perfusion scan and make a comparison with trans thoracic echocardiography.
Material and Methods: In this cross-sectional descriptive study during Sep 2001- Dec 2002, 68 patients suspected of IHD who were referred to nuclear Medicine Department of Imam Reza Hospital in Mashhad University of Medical Sciences were under taken gated myocardial perfusion SPECT, and then referred to echocardiography unit for trans thoracic echocardiography. LV volume, ejection fraction, regional wall motion in different views of 2D-echo was recorded and the results were compared by descriptive statistics.
Results:This study was performed on 68 patients. The mean age of patients was 52.8 (min: 38, Max: 75). 54% of patients were male and 46% were female. Mean end systolic volumes of LV was 32.4ml (sd: 37.1) estimated by echocardiography and 68.3ml (sd: 52.2) stimated by radionuclide scan (pv: 0.00). Mean end diastolic volume of LV was 129.6ml (sd: 45.8) in echocardiography and 143.7ml (sd: 46.23) in radionuclide scanning (pv: 0.00). Mean ejection fraction value of LV was 54.6 (sd: 12.44) estimated by echocardiography and 54 (sd: 12.94) by radionuclide scan (pv: 0.00).‍
Conclusions: Left ventricular end systolic and diastolic volumes and ejection fraction, obtained by gated myocardial perfusion scan and echocardiography, had significant statistic correlations and estimation of LV wall motions and ejection fraction by gated SPECT was as echocardiography.


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