Sinus Histiocytosis with Massive Lymphadenopathy (Rosai-Dorfman Disease): A Case Report

Document Type : Case report



Introduction: Sinus histiocytosis with massive lymphadenopathy (SHML) or Rosai-Dorfman disease (RDD) is a rare benign histiocytic disease of unknown etiology, usually associated with lymph node enlargement in various superficial or deep sites.
It usually shows a prolonged clinical course with occasional exacerbation and remission phases.
In this article case of RDD in a 5-year-old male with large right inguinal and bilateral cervical lymphadenopathies were, occasional fever and anemia was described. The clinical presentation, histopathologic characteristics, and treatments of RDD were discussed.

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