Document Type : Research Paper
Authors
1
MSc of Midwifery, Karaj Branch, Islamic Azad University, Karaj, Iran
2
Assistant professor of Midwifery, Karaj Branch, Islamic Azad University, Karaj, Iran
3
Assistant Professor of Romatology, Mashhad University of Medical Sciences, Mashhad, Iran
4
Assistant Professor of Biostatistics, Tabriz Health Services Management Research Center, Faculty of Health and Nutrition,Tabriz University of Medical Sciences, Tabriz, Iran
5
Assistant professor of exercise physiology, Karaj Branch, Islamic Azad University, Karaj, Iran
Abstract
Introduction
Polycystic ovarian syndrome (PCOS) is the most common endocrinopathy in women before menopause. However, changing the life style is mentioned as the first line of therapeutic strategy; the researches have shown the different results. The purpose of this study was to investigate the effects of a conducted program based on diet and physical activity on clinical and laboratory characteristics of obese PCOS women.
Materials and Methods
Fifty women with PCOS randomly divided into two groups. The intervention plan consisted of a 12-week exercise and diet program for one of the group, while the other did not receive such interventions. Participant’s characteristics including demographic, menstrual status, clinical characteristics of hyper-androgenemia, as well as biochemical, hormonal and abdominal ultra-sonography data were evaluated at baseline and 3 months after intervention.
Results
The mean (Standard deviation) of age and body mass index (BMI) were 25.9 (4.13) year, 22.11 (3.96) year and 31.4 (4.85) kg/m2 and 28.81 (3.81) kg/m2 in experimental and control groups respectively. There were significant differences between experimental and control groups for follicle stimulating hormone (FSH) and luteinizing hormone (LH) (p=0.01), total testosterone (p=0.005), free testosterone (p=0.004), estradiol (p=0.03), sex- hormone bounding globulin (SHBG), triiodotyronine (T3), thyroxine (T4) and TSH (p=0.001), 17 hydroxy progesterone and triglycerides (p=0.03), total cholesterol (p=0.05), BMI (p=0.03), the ultrasound exam, oligomenorrhea, hirsutism and acne (p <0.001) and alopecia (p=0.01).
Conclusion
Regular exercise and dietary intervention can be recommended as non-pharmacological interventions to PCOS patients
Keywords
)