Document Type : Research Paper
Authors
1
Department of Microbiology, Faculty of Sciences, Agriculture and Modern Technology, Shiraz Branch, Islamic Azad University, Shiraz, Iran.
2
Gasteroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
3
Department of Laboratory Sciences, School of Allied Medical Sciences, Ahvaze Jundishapur University of Medical Sciences, Ahvaze Iran.
Abstract
Introduction: Helicobacter pylori is one of the most common infectious bacteria in the world and the most common cause of type B gastritis. The aim of this study is to determine the amount of anti-H. pylori antibodies in healthy and asymptomatic people.
Methods: A number of 264 people in two age groups, 15-20 and 45-50 years, were selected after completing the questionnaire. A serum sample was prepared from each person and the amount of IgG and IgA antibodies was checked by ELISA method.
Results: The frequency of antibodies in the entire population and in two age groups and by gender (girls, boys, women and men) in the case of IgG is 57.2, 52.9, 32.3, 69.7 and 7.7 respectively and in the case of IgA it was 10.6%, 7.1%, 4.8%, 5.2% and 15.2% respectively. In terms of the amount of positive IgG and IgA, a significant difference was observed between the two age groups (p<0.05), so that the amount of the two antibodies was higher in the age group of 45-50 years. In terms of gender, no significant difference was observed in the entire population. Also, the amount of positive cases had a direct relationship with the number of family members and an inverse relationship with the income level.
Conclusion: Therefore, age and sex (in young people), number of family members, and income had an effect on the frequency of antibodies. It is suggested to improve the economic, health, medical and cultural status of the society in order to reduce the frequency of infection with H. pylori.
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