Medical Journal of Mashhad university of Medical Sciences

Medical Journal of Mashhad university of Medical Sciences

Evaluation of clinical manifestations of infants 2 to 18 months with the possibility of allergy to cow's milk protein referred to the gastrointestinal clinic and common methods of treatment and response to treatment

Document Type : Research Paper

Authors
zahra Rostami 1
Mohammad Esagh Rozeh 2
MARYAM RASOLI 3
1 Department of Biostatistics, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran.
2 Assistant Professor of Pediatrics Gastroenterology Department of Pediatrics, School of Medicine Ayatollah Mousavi Hospital Zanjan University of Medical Sciences, Zanjan, Iran
3 Student Research Committee, Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran
10.22038/mjms.2023.70054.4159
Abstract
Background:
Allergy to cow's protein without treatment can cause problems such as insufficient growth in height and weight of children. The present study was conducted with the aim of comparing 4 types of treatment regimens in cow's milk protein sensitivity.
Method:
In this cross-sectional study, a total number of 50 infants with cow's milk feeding syndrome who referred to the pediatric clinic were selected. The rate of response to therapeutic regimens, including the elimination of dairy from the mother's diet, semi-hydrolyzed formula, fully hydrolyzed formula, and the amino acid-based formula was evaluated in children. The tool for compiling a checklist was prepared based on the literature review and under the supervision of a specialist in pediatrics. The analysis was done in spss19 software.
Results:
In this study, the most common findings of visiting a doctor were 31 (68 %) gastrointestinal bleeding, and 14 (28 %) dermatitis. The rate of response to different treatments was 6 (12%), semi-hydrolyzed formula 2 (4%), fully hydrolyzed formula 8 (14%), and formula based on amino acids 34 (68%), respectively, to remove dairy products from the mother's diet.
Conclusion:
The most common finding in infants with cow's milk protein allergy referred to a pediatric gastroenterology clinic was gastrointestinal bleeding, and the best treatment responses were to the formula based on amino acids.
Keywords
allergy
cow`s milk protein
treatment
Subjects
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Medical Journal of Mashhad university of Medical Sciences
Volume 65, Issue 6
January and February 2023
Pages 2268-2272