Medical Journal of Mashhad university of Medical Sciences

Medical Journal of Mashhad university of Medical Sciences

The effect of eight weeks of HIIT training compared to MICT on brain-derived neurotrophic factor (BDNF) in inactive overweight women

Document Type : Research Paper

Authors
yasaman arabi 1
Sajad Arshadi 2
Valiollah Shahedi 3
Abdol Ali Banaiefar 2
1 PhD student in Exercise Physiology, South Tehran Branch, Islamic Azad University, Tehran, Iran.
2 Associate Professor, Department of Exercise Physiology, South Tehran Branch, Islamic Azad University, Tehran, Iran
3 Assistant Professor, Department of Exercise Physiology, Parand Branch, Islamic Azad University, Tehran, Iran
10.22038/mjms.2025.86071.4923
Abstract
Introduction
The increasing prevalence of overweight and obesity can lead to an increase in the prevalence of cardiovascular diseases, asthma, type 2 diabetes, atherosclerosis, and consequently increased mortality. In addition to storing energy, adipose tissue acts as an endocrine organ that is capable of secreting a large number of different adipokines, cytokines, and chemokines. BDNF is a neurogrowth factor that is effective in cognitive function, fat and sugar metabolism, and also the pathophysiology of obesity and metabolic syndrome.
Material and Methods
In the present study, 45 overweight women who were recruited in Tehran were randomly divided into three groups of 15: high-intensity interval training (HIIT) group, moderate-intensity continuous training (MICT) group, and control group. The training groups performed three sessions per week for eight weeks according to the standard protocol. Blood sampling 48 hours before the start of the period and 48 hours after the last training session, including 10 cc of blood, was measured from the brachial vein in fasting and sitting conditions. One-way ANOVA and Tukey's post hoc test were used to compare the data at a confidence level of 95%.
Conclusion
Both types of HIIT and MICT exercises caused a decrease in the level of BDNF, but considering that MICT exercises had better effects on increasing this index, it can be stated that in the present study this training method can be more effective in overweight people.
Keywords
Maximal intensity interval exercises
moderate intensity continuous interval exercises
brain-derived neurotrophic factor
overweight
Subjects
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Medical Journal of Mashhad university of Medical Sciences
Volume 67, Issue 5 - Serial Number 5
September and October 2024
Pages 169-179