The Result of Transrectal Ultrasound Guided 10-14 Cores Biopsies of the Prostate

Document Type : Research Paper

Authors

1 Professor of Urology, Mashhad University of medical Science Mashhad, Iran

2 Resident of Urology,Mashhad University of Medical Sciences,Mashhad, Iran

3 Urologist, Mashhad, Iran

Abstract

Introduction
The diagnostic tool in prostate cancer is prostate biopsy but recently classic biopsy has low efficacy. In recent years, trans-rectal ultrasound guided prostate biopsy is a standard method in prostate cancer diagnosis. In the present study, we report our experience about ultrasound guided 10-14 core prostate biopsies at a hospital in Mashhad.
Materials and Methods
The study included 196 men with PSA values of ≥10 ng/ml or 10 ng/ml ≥PSA level ≥4 ng/ml and Free PSA/ Total PSA ratio was less than 20%. These patients underwent transrectal ultrasound (TRUS)-guided 10-14 core prostate biopsy.
Results
Of the 196 patients, cancer in 73 patients (37.2%), intraepithelial neoplasia in 14 patients (7.1%) and benign prostatic hyperplasia in 108 patients (55.1%) were diagnosed. Transrectal ultrasound guided 10-14 core prostate biopsy diagnosed prostatic cancer in 25% of 14 patients who had no prostatic cancer with traditional biopsy. There were non significant associations between age and total and free PSA. There was a non significant correlation between the free PSA and Gleason score, but there was a significant correlation between the Gleason score and total PSA.
Conclusion
This study shows that the TRUS-guided 10-14 core biopsies yield a better prostate cancer detection rate than the classic biopsy.

Keywords

References

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medical journal of mashhad university of medical sciences
Volume 54, Issue 3 - Serial Number 3
September and October 2010
Pages 172-176

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