Brain Venous Thrombosis

Document Type : Research Paper

Authors

1 Associate Professor of Neurology, Mashhad University of Medical sciences, Mashhad, Iran

2 Neurologist, Mashhad University of Medical sciences, Mashhad, Iran

3 Assistant Professor of Neurology, Mashhad University of Medical sciences, Mashhad, Iran

4 Assistant of Neurology, Mashhad University of Medical sciences, Mashhad, Iran

Abstract

Introduction
The First Cerebral vein thrombosis was reported in 1825. Early diagnosis is very important, because early treatment can prevent mortality in most eases. Also, cerebral vein thrombosis is preventable by finding the underlying etiology. True incidence of cerebral vein thrombosis is not predicative.
Materials and Methods
This descriptive study was performed from 2005 through 2006 on patients referred to Qaem Hospital neurological emergency ward. All of the patients with clinical feature of ICP rising were evaluated and underwent CT scan and MRI of brain. In cases suspicious to cerebral vein thrombosis, the disease was actually diagnosed with MR venography of brain, after discharge Patients were followed up every week for 3 weeks in neurological clinic of Qaem Hospital.
Results
From 20 evaluated patients, 70% were female and 30% were male, in which the ratio of F/M was 3/2. Patients mean age was 30 year. The most clinical feature was headache. Underlying etiologies in above patients were: OCP consumption, post partum period, media otitis, nephrotic syndrome and Crystal abuse. In MRI and MRV assays of studied patients, 20% had superior sagital sinus, 10% lateral sinus, 5% sigmoid sinus and 65% had superior sagital and lateral sinus involvement simultaneously.
Conclusion
In patients who refer having headache and papilla edema, cerebral vein thrombosis should be considered. Early diagnosis is achieved by precise diagnostic methods like MRI and MRV, and the prevention of severe irreversible and fatal side effects of disease with the early treatment.

Keywords

References

1- Bousser MG, Barnett HJM. Cerebral venous thrombosis. In: Barnett HJM, Mohr JP, Stein BM. Stroke.3rd
ed.Philadelphia: Churghill-Livingstone; 1998.p.623-642.
2- Biller J, Love B. Ischemic cerebrovascular Disease. In: Bradley WG, Daroff RB, Fenichel GM. Neurology in clinical
practice. 4thed. Philadelphia: Butterworth-Heinemann; 2004.p.1243-1246.
3- Ropper AH, Brown RH. Adams and Victor’s Principle of Neurology. 8thed. New York: McGraw-Hill; 2005.p.734-738.
4- Fishman RA. Cerebral veins and sinuses. In: Rowland LP. Merriit Neurology. 11th ed. Philadelphia: Lippincott
WillIams & Wilkins; 2005.p.338-341.
5- Dentali F, Gianni M, Growth MA. Natural history of cerebral vein thrombosis. Blood 2006; 108:1129-1134.
6- Black C, Kaye JA. Clinical risk factors for venous thromboembolus in users of the combined oral contraceptive .Br J
clin Phamacol 2002; 53: 637-640.
7- Raes Mc, Tranhoschulman S. Effect of patient sex on risk of recurrent venous thromboembolism . Ameta – analy.
Lancet 2006; 368: 371-378.
8 - Koster T, Small R. Oral contraceptive and venous thromboembolies. J Intermed 1995; 238:31-37.
9- Kapessidou Y, Vokaer M, Lavreys M, Bier JC, Boogaerts JG. Cases report. Cerebral vein thrombosis after
subarachnoid analgesics for labour. Can J Anaesth 2006; 53:1015-1019.
10- Wiste E, Sokinska W. Cerebral venous sinus thrombosis. Neurology 2006; 67: 814-819. 
medical journal of mashhad university of medical sciences
Volume 52, Issue 3 - Serial Number 3
September and October 2008
Pages 147-150

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