Investigation of the antimicrobial properties of several medicinal plants on antibiotic-resistant Escherichia coli isolated from poultry feces

Document Type : Research Paper

Authors

1 Department of Laboratory Sciences - Faculty of Paramedical Sciences - Mashhad University of Medical Sciences - Mashhad

2 Zabol University of Medical Sciences - Zabol - Iran

3 Assistant Professor of Obstetrics and Gynecology, Perinatology Fellowship - Imam Hossein Hospital - Shahid Beheshti University of Medical Sciences, Tehran - Iran)

4 Emergency Medical Department - Zabol University of Medical Sciences - Zabol - Iran

5 Zabol University of Medical Sciences-Zabol

6 National University of Zahedan-Sistan and Baluchestan

7 Department of Pathology, Faculty of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran

10.22038/mjms.2025.84774.4869

Abstract

Inappropriate use of antibiotics in human and animal health and their long-term use as growth promoters in various doses in the poultry and livestock industry has led to increased antibiotic resistance. Multidrug resistance in Escherichia coli has become a worrying issue that is increasingly observed worldwide. Escherichia coli is inherently sensitive to all antimicrobial agents, but this type of bacteria has a great capacity to accumulate antibiotic resistance genes through horizontal gene transfer. The aim of this study is to investigate the antibiotic resistance pattern and investigate the antimicrobial properties of several medicinal plants on pathogenic bacteria. 10 g of dry matter of Karla, Oleander, Hyssop and Black Crownwort plants were placed in 100 cc of ethanol solvent and shaken for 24 hours. After 24 hours, it was filtered and dried in an oven. The antimicrobial properties were investigated at a concentration of 50 mg/ml by the well method. The results showed that Escherichia coli isolates were resistant to the antibiotics ceftazidime, gentamicin, azithromycin, and amoxiclav, respectively, and the largest inhibitory zone diameter was associated with the two plants, Carla and Oleander, which can be used in the treatment of infections caused by this bacteria.

Keywords

Main Subjects


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